Gene Information

Name : Halhy_4891 (Halhy_4891)
Accession : YP_004449593.1
Strain : Haliscomenobacter hydrossis DSM 1100
Genome accession: NC_015510
Putative virulence/resistance : Virulence
Product : Restriction endonuclease, type I, EcoRI, R subunit/Type III
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 6208553 - 6211648 bp
Length : 3096 bp
Strand : -
Note : COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR007409:IPR006935:IPR014001; KEGG: chu:CHU_2936 restriction enzyme type I helicase subunit; type I restriction enzyme HsdR; PFAM: R

DNA sequence :
ATGCCCAGTAAAACCAACGAACAGGCCCTGGAAGCGGCCATTGAAAAACGCCTGACCGGCAGCTGTCTGGAAGAACTCCG
CGAGCAGGGTAGCAGCGGAATGGAAGCGCAGGAAAAAGCCCGCCGTTTCTACCGCTCGGGCAATGGCTACTACCTCGGCT
TCCCCCAGGATTTTAACGCCCAATGGGCCATTGATGAATACCGTTTTTGGGATTTTTTGGAAAACACCCAGGCCGAAGAA
CTCGCCAAGCTCCAAAAACAAGCCGAATGGAAGCGCAAGATCCTGGAGCGCCTGGATCGCATGATCAAAAAATACGGCAT
CCTGCGCCTCTTCCGCAAGGGTTTGGATGTGGACGATGCCCACTTCACGCTGCTCTACCCTTTGCCTTTGGCCAGCAGCA
GCGAAACGGTCAAAAACAACTTTGAACAAAACCAGTTCAGCGCCACCCGCCAGCTGCGCTACTCGCTGGCCAACCCCGGC
GAGGAAATCGACCTGGTGCTTTTTGCCAATGGCCTGCCCTTCGCCACCCTGGAACTCAAAAACCACTGGACGGGCCAAAA
CGCCAAGGTCCACGGCCAAAACCAATACCGCTACAAAAGAGACATCACCCAGCCGCTCTTGAATTTTGGGCGCTGCATCG
TGCACTTTGCCGTGGATACCGAGGAGGTGTACATGACCACCAAACTCAATGGCCCGGGCACCTTCTTTTTGCCCCTCAAC
CGGGGCCACAACTTCGGCAAAGGCAACCCACCCAACCCGCAGGGGCACAAAACAGCCTACCTCTGGGAAGACATCCTGAC
CCGGCAGAGTGTGGCCAATATCATCCAGCATTTTGTACGTTTTGATGGCAAAGACAACGATCCGCTGGCCAAAAAGACCC
TGTATTTTCCGCGTTACCACCAGTTGGATGTGGTGCGCCGCCTGGTGGGTCACGCCAGCAAGCACGGCGTGGGACATACC
TACCTGATCCAGCACTCAGCTGGCTCGGGCAAGTCCAATTCCATCACCTGGGCCGCCTACCAACTCATCGAAACCTATCC
CGAATCGGAGACCCTGCCGGGCAGCAAAGGCCAGGACAAGCCCTTGTTTGACTCAGTCATCGTGGTGACGGATCGGCGCT
TGCTGGACAAACAACTGCGCGAGAACATCCGGGAGTTTTCGGAGGTCAAAAACATCGTGGCACCCGCTTACTCTTCGGCA
GACTTGAAGAGTGCCCTGGAAGGTGGCAAAAAGATCATCATCACCACCATCCAGAAATTCCCCTTCATCATCGATGGCAT
TGCCGACCTGAGCTACAAACGTTTTGCGGTCATCATCGATGAGGCGCACAGCAGCCAGAGTGGCACCGCCGCCGGAAAGA
TGAACCAGGCCATGGGCAACAGTGCCAGCAGTACGGAAGAGGAGGACGAAGACCCCCAGGACAAAATTCTGGAAGCCATG
CGCTCGCGCAAAATGCGGGGCAACGCCTCCTACCTGGCCTTCACCGCTACGCCCAAAAACGCCACGCTGGAACGTTTTGG
CACCCGCCAGCCCGATGGCAAGTACATTCCCTTCGATTTGTACTCCATGAAACAGGCCATCGAAGAGGGTTTCATCCTCG
ATGTTTTGGCCAATTACACGACCTACAAGAGTTATTACGAAATCGAAAAATCCATCGAGGAAAACCCGCTGTTTGATACC
GTTAAGGCGCAAAAGAAGCTGCGCAATTTTGTGGAGCAAAACCAACAGACCATCGGCACCAAGGCCGAAATCATGCTGGA
TCATTTCATCACAAAACTGGTCAATACCAAAAAACTGAAGGGCAAAGCCAAAGCCATCGTGGCCACCCAAAGCATCGAAT
CGGCCATCAACTACTATTTTACGCTCCAAAAATTACTCGACGCCCGAGGCAATCCCTTCCGCATCGCGATTGCTTTTTCG
GGTGCAAAAAAAATCAAGGGCATCGAGTACACCGAAGACAGCATCAATGATTTTCCCGCCGCTCTGGATACCGCCAAGCC
CACCGAGGCCGGGTACATCAGCGATAAAATTGCCCGCTACTTCGATCTGGACGAATACCGCATGCTGGTGGTGGCCAACA
AGTACCTGACGGGCTTCGACCAACCCAAACTCAGCGCCATGTACGTGGACAAAAAGCTGCAAGGGGTACTGGCGGTGCAG
GCTTTGTCGCGGCTCAACCGCTCGGCAGACAAACTGGGCAAAAAGACCGAGGATTTGTTCATCCTCGATTTTTACAATTC
CACCGAAGACATCAAGAAGGCTTTTGATCCGTTTTATACCTCCACCTCCCTGAGCCAGGCCACCGACGTAAACGTGCTCC
ACGAGCTCAAAGCCCAGCTGGACGATACGGGCGTGTACGAGTGGCAGGAAGTGGAAGCTTTTGTGGCCAAATACTTCGAG
GGCGTCAACGCCCAGGAGCTGAGCCCCATCATCGATTTGGCCGCCGACCGTTTCAACGCCGCCCTGGAACTGGAAGACCA
GGCCAAGGCCGATTACAAAATCAAGGCCAAACAGTTTGTCAAGATTTACGGACAAATGGCCTCCATTTTACCCTACGAAA
TCCTGGCCTGGGAGAAGCTGTTCTGGTTCCTCAAATTCCTGATCCCCAAACTCATCATCATCGACCCCACTCAGGATACC
CTGGACGAACTCCTCAACGCGGTCGACCTCTCCACCTATGGCCTAGAACGGGTAAAACTGAATGCCTCCATCGGCCTGGA
TGCCAGCGAAACGGAACTCGATCCCCAGAACTCCAACCCGCGGGCGGCGCACAGCGGCGAGGCGGATGAAGACCCCCTGG
ATTTGATCATCAAGAGTTTTAACGAGCGCTGGTTTCAGGGTTGGGAGGCTACGCCGGAGGAGCAGCGCGTGAAATTTGTC
AATCTGGCCCAACGCATCCAGGAACACCCGGATTTCCAGGAAAAGTATGCCGACAATGCTGACCCCCAAAACCGGGAGAT
TGCTTTCAAAAAGATCTTTGACGACGTGATGGGCAAACAACGCAAGAATGAATTGGACCTTTATCGGCTGTTGTCACAGG
ATGAGAGTTTTAAAGTGGCGATGTTGGATACGTTGAAGCGGATTTTGAGGGCCTGA

Protein sequence :
MPSKTNEQALEAAIEKRLTGSCLEELREQGSSGMEAQEKARRFYRSGNGYYLGFPQDFNAQWAIDEYRFWDFLENTQAEE
LAKLQKQAEWKRKILERLDRMIKKYGILRLFRKGLDVDDAHFTLLYPLPLASSSETVKNNFEQNQFSATRQLRYSLANPG
EEIDLVLFANGLPFATLELKNHWTGQNAKVHGQNQYRYKRDITQPLLNFGRCIVHFAVDTEEVYMTTKLNGPGTFFLPLN
RGHNFGKGNPPNPQGHKTAYLWEDILTRQSVANIIQHFVRFDGKDNDPLAKKTLYFPRYHQLDVVRRLVGHASKHGVGHT
YLIQHSAGSGKSNSITWAAYQLIETYPESETLPGSKGQDKPLFDSVIVVTDRRLLDKQLRENIREFSEVKNIVAPAYSSA
DLKSALEGGKKIIITTIQKFPFIIDGIADLSYKRFAVIIDEAHSSQSGTAAGKMNQAMGNSASSTEEEDEDPQDKILEAM
RSRKMRGNASYLAFTATPKNATLERFGTRQPDGKYIPFDLYSMKQAIEEGFILDVLANYTTYKSYYEIEKSIEENPLFDT
VKAQKKLRNFVEQNQQTIGTKAEIMLDHFITKLVNTKKLKGKAKAIVATQSIESAINYYFTLQKLLDARGNPFRIAIAFS
GAKKIKGIEYTEDSINDFPAALDTAKPTEAGYISDKIARYFDLDEYRMLVVANKYLTGFDQPKLSAMYVDKKLQGVLAVQ
ALSRLNRSADKLGKKTEDLFILDFYNSTEDIKKAFDPFYTSTSLSQATDVNVLHELKAQLDDTGVYEWQEVEAFVAKYFE
GVNAQELSPIIDLAADRFNAALELEDQAKADYKIKAKQFVKIYGQMASILPYEILAWEKLFWFLKFLIPKLIIIDPTQDT
LDELLNAVDLSTYGLERVKLNASIGLDASETELDPQNSNPRAAHSGEADEDPLDLIIKSFNERWFQGWEATPEEQRVKFV
NLAQRIQEHPDFQEKYADNADPQNREIAFKKIFDDVMGKQRKNELDLYRLLSQDESFKVAMLDTLKRILRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VPI2_0013c ACA01830.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 0.0 67
VC1765 NP_231400.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 0.0 67
VC0395_A1363 YP_001217306.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 0.0 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Halhy_4891 YP_004449593.1 Restriction endonuclease, type I, EcoRI, R subunit/Type III VFG1098 Protein 0.0 67