Gene Information

Name : Halhy_4317 (Halhy_4317)
Accession : YP_004449034.1
Strain : Haliscomenobacter hydrossis DSM 1100
Genome accession: NC_015510
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 5428599 - 5429744 bp
Length : 1146 bp
Strand : +
Note : COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: sli:Slin_5637 cystathionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cystathionine gamma-lyase; SPTR: Cystathionine b

DNA sequence :
ATGAAATTCGGAACCAAAGCCATCCATGCGGGCATTGAGCCAGATCCTTCCACTGGAGCCGTCATGACCCCCATTTATCA
GACCTCTACCTATGCGCAGGAAGCACCCGGTGTCCACCAGGGGTATGAGTACGCACGTACCCAAAACCCCACCCGTTCGG
TGTTGGAGAAAAACCTGGCGGCGCTGGAAAACGGCCAACACGCCGTGTGTTTCAGCAGTGGACTTGCGGCTATGGATGCC
ATCATCCGTTTGCTTAACCCGGGCGATGAATTGATTTCGAGCAATGACTTGTACGGGGGCTCTTACCGCCAACTGGTACG
GGTACACGGGCGGTATGGGCTGGTTTCTCATTTCGTTCCAATGCAGGATTTGGGCAGCATTGCGGCAAAAATCAATTCCA
AAACCCGCATGTTGTGGATCGAAACACCTACGAATCCAATGCTTAGTCTGGTCGACATCAAAGCGGTATGTACCCTGGCG
CGTGAGCAGGGCATCCTGACTTGTGTGGACAATACCTTTGCCTCTCCTTACCTACAAAATCCACTCGATTTGGGTGCTGA
TATCGTGATGCATTCGGCTACCAAATACATCGGAGGGCACTCGGACGTGATCCACGGCGCGGTGATCACCAACAATGATT
CGATTGCCCAGCAATTGCGGTTTTTGCAAAATGCCATTGGCGCTGTGCCTGGGCCTCAAGACTGTTTCCTCATTTTGCGC
GGCATCAAAACCTTACATTTGCGGGTAGAACGGGCTTGTCAGAATGCCGAAAAAATTGCGCAGTTTTTGCGCAATCACCC
CAAAGTGCGCAAAACATACTACCCGGGATTCAGCGATCATCCCGGGCACGCTATCGCCAAAAAACAAATGCGGCACTACG
GCGCGATGGTTTCTTTTGATTTGCATACCGATACCCTCGAATACGCCACAACCGTACTGGCCAATACGCAACTGTTCACC
CTGGCAGAATCATTGGGAGGCGTTGAATCCCTAATCGGCCATCCTGCTACCATGACCCACGCCAGCATTCCGCTAGAAGA
GCGCTACAAAGTGGGCTTGACCAATTCCCTGATCCGCCTGAGTGTAGGGGTAGAAGATGTGGAGGATTTGATCGAAGATT
TGGGGCAGGCTTTGGATCGACTTTAA

Protein sequence :
MKFGTKAIHAGIEPDPSTGAVMTPIYQTSTYAQEAPGVHQGYEYARTQNPTRSVLEKNLAALENGQHAVCFSSGLAAMDA
IIRLLNPGDELISSNDLYGGSYRQLVRVHGRYGLVSHFVPMQDLGSIAAKINSKTRMLWIETPTNPMLSLVDIKAVCTLA
REQGILTCVDNTFASPYLQNPLDLGADIVMHSATKYIGGHSDVIHGAVITNNDSIAQQLRFLQNAIGAVPGPQDCFLILR
GIKTLHLRVERACQNAEKIAQFLRNHPKVRKTYYPGFSDHPGHAIAKKQMRHYGAMVSFDLHTDTLEYATTVLANTQLFT
LAESLGGVESLIGHPATMTHASIPLEERYKVGLTNSLIRLSVGVEDVEDLIEDLGQALDRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-89 51
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-88 50
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-66 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Halhy_4317 YP_004449034.1 cystathionine gamma-lyase BAC0207 Protein 5e-69 41