Gene Information

Name : AGROH133_13586 (AGROH133_13586)
Accession : YP_004444556.1
Strain :
Genome accession: NC_015508
Putative virulence/resistance : Resistance
Product : Bcr/CflA subfamily drug resistance transporter
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 1916605 - 1917795 bp
Length : 1191 bp
Strand : +
Note : Permeases of the major facilitator superfamily

DNA sequence :
ATGTCTATTCCAACTCCCGTTTGGGGGAGATCGCTGTTGGCAGCAATGCTGCTGATGGCTCCCTTTGATATTCTCGCCTC
GCTGGCCATGGATATTTACCTGCCGGTCGTCCCCATCATGCCGGAAGCCCTCGGCACGACACCGGTGGTGGTTCAACTCA
CGCTCACCGTTTACATGGTGATGCTCGGCCTTGGGCAAATCGTGTTTGGCCCCATCTCCGACCGCATCGGTCGCCGGCCC
GTCTTGATCGGCGGTGCCCTGCTGTTCGTCGTGGCCTCGTTCTGCCTCGCAGCTGTGACAACGGCGAGCGCCTTTATCGT
TTTCCGGTTCCTTCAGTCGGCTGGAGCGGCGGCGGCATTGGTCGCCACTTTCGCCACCGTTCGCGACGTCTATGCGGATC
GTCCGGAAGCAACGACGATATACGGAACGTTCAGCTCCATTCTCGCATTCGTCCCGGCACTCGGTCCGATTGTCGGGGCG
GTCATCGCCAATGAATTCGGCTGGCGTGCCATCTTCGTCACCCTGGGCGCGGCAGCTTTCATTGCGACGGTTGCCGCAGG
GAGGAACTGGAGCGAAACCCGACCGGCGACGGCAACGATGTCACGCCCATCGCCTTTGCGCATGTTGGGCAGTGGTCGCT
TCTGGACTTATACGCTTGGGTTCAGCACTGCCATGGGAACGTTTTTCGTATTCTTCTCCACCGCTCCGCTCGTCATGATT
GCCAGGGCAGGTCTCTCCGAGGTGGAGTTCAGCCTGGCTTTTGCAACCGTCGCAATCGCAATGATCGTTACCACCCGTTT
TGCGAAGTTTTTCGTTGCCAGATGGGGTGTGCAGGGCAGTCTCGTGAGGGGCATGGCCCTGTTGTTGGTGGGGGCGTTTC
TGTTCACTGCAGGTGAAGTCGGGGCGGTTCCGTCATTTTTGACGTTTATCGTACCGATGTGGGTCATGGCGGTCGGAATC
GTTTTTACGGTTTCAGTCACCGCCAATGGCGCGCTGGAGGACTTCGGGCACATGGCTGGAACAGCCGTCGCCTTCTATTT
CTGCATTCAAAGTCTGTTTGTGGGAATAGCGGGCACCTTGGCTGTCGTCATTCTGCCGGGTGATGCGGCATGGCCGGTGA
TCGCCTATTCATCGATCATGGCCTGCCTTGTCCTGACGGCGCTATATTTGTTGAACCGCCGGAATATCTGA

Protein sequence :
MSIPTPVWGRSLLAAMLLMAPFDILASLAMDIYLPVVPIMPEALGTTPVVVQLTLTVYMVMLGLGQIVFGPISDRIGRRP
VLIGGALLFVVASFCLAAVTTASAFIVFRFLQSAGAAAALVATFATVRDVYADRPEATTIYGTFSSILAFVPALGPIVGA
VIANEFGWRAIFVTLGAAAFIATVAAGRNWSETRPATATMSRPSPLRMLGSGRFWTYTLGFSTAMGTFFVFFSTAPLVMI
ARAGLSEVEFSLAFATVAIAMIVTTRFAKFFVARWGVQGSLVRGMALLLVGAFLFTAGEVGAVPSFLTFIVPMWVMAVGI
VFTVSVTANGALEDFGHMAGTAVAFYFCIQSLFVGIAGTLAVVILPGDAAWPVIAYSSIMACLVLTALYLLNRRNI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
flo AAK02049.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 1e-101 65
floRc AGK06972.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 1e-101 65
floRc AGK07102.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 1e-101 65
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein Not tested ICEPmu1 Protein 4e-99 65
cmlA9 ABZ01840.1 CmlA9 chloramphenicol efflux protein Not tested SGI2 Protein 2e-99 63
cmlA CAJ77032.1 chloramphenicol and florfenicol resistance protein Not tested AbaR1 Protein 2e-99 63
cml(A)5 ACY75522.1 CmLA(5) Not tested Tn6060 Protein 2e-74 51
cmlA5 CAJ77046.1 Chloramphenicol resistance protein Not tested AbaR1 Protein 3e-74 51

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AGROH133_13586 YP_004444556.1 Bcr/CflA subfamily drug resistance transporter DQ984668.gene.p01 Protein 1e-74 51
AGROH133_13586 YP_004444556.1 Bcr/CflA subfamily drug resistance transporter AF294653.1.gene4.p01 Protein 8e-75 51
AGROH133_13586 YP_004444556.1 Bcr/CflA subfamily drug resistance transporter DQ522237.1.gene4.p01 Protein 1e-74 51
AGROH133_13586 YP_004444556.1 Bcr/CflA subfamily drug resistance transporter NC_010410.6003586.p0 Protein 1e-74 51
AGROH133_13586 YP_004444556.1 Bcr/CflA subfamily drug resistance transporter AF156486.gene.p01 Protein 8e-73 50