Gene Information

Name : AGROH133_13523 (AGROH133_13523)
Accession : YP_004444533.1
Strain :
Genome accession: NC_015508
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase protein
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 1884522 - 1886141 bp
Length : 1620 bp
Strand : -
Note : 2,3-dihydroxybenzoate-AMP ligase; Peptide arylation enzymes

DNA sequence : 
ATGACAATCGAATTTGAACGCTGGCCCGAAGATCTGGCGCGCCGATACCGCGACCGCGGCTACTGGATCGACAGACCGCT
CAGCGACATCCTCACCCAGCAGGTGGAACTTCGGCCGGACGCGACCGCGCTGATCTGCGGCGACCGCCGCTTCACCTATG
CCGATCTCGACCGGCAATCTTCCAATCTTGCCGGGCATCTGGCTGCCGCCGGGATCGGCAGGGGCGATACGGCACTGGTG
CAATTACCAAATATCGCGGAGTTCTATCTCGTCTTTTTCGCTCTGATGAAAATCGGCGCTGCACCCGTCAATGCGCTTTT
CAGCCATCGTCGGCTGGAAATGACCTCCTATGCGGAACAGATTGCGCCAAAGCTGGTGATCGGCTCGCGTTCCCACGAGC
TTTTTGCCAATGACACGTTTCTGGAGGCGCTGAAGCTCACCTCTCCGCGGCTTGCCGTGACGCTGCTGCTTGGTGAGACG
GAACCGCAGCGCAGCCTCGAACAATGGCTCTCATCACCCGCCGAAAATGCGCCGCATTACGGCCCTTCGGCAGCCGATGA
GGTAGCATTGTTCCAGCTTTCCGGCGGCAGCACCGGAACGCCGAAACTGATCCCCCGCACGCATAACGACTATGACTACA
GCGCCCGGGCCAGTGCGGAAATCTGCGAGCTGACGCCGCAGACCCGTTTCCTCTGCGCCATTCCGGTGGCGCATAATTAC
CCCATGAGTTCGCCGGGTGCGCTTGGCGTGTTCCACGCTGGCGGCACCGTGGTAATGGCGGCCAATCCCGAGCCGCTTGC
CTGCTTCGACCTCATCGAAAAACATGGCATCGACATTGTGCCTCTGGTGCCGCCGGCCGTGGCCCTGTGGTTACAGGTGG
CGCCCGCCCATCGCGAACGGCTGAAATCCCTCAAGCTGCTGCAGGTCGGCGGCGCAAGCTTTGCTGAAGCTTTAGCGCGT
CAGGTGCCGCAGGTGCTGGGTTGCGCCCTCCAGCAGGTCTTCGGCATGGCGGAAGGTCTGGTGAACTATACCCGCGCCGG
TGATCCCGACCATATTGTCTTAACCACGCAAGGGCGGCCGATCAGCCCGGATGACGAGATCCGCATCGTTGACGAGGACG
GCAACGACGTTCCAGAAGGCGAAGCCGGCATGCTGGCGACGCGCGGCCCCTATACGTTTCGCGGATATTACCGCGCCGCC
GAGCACAGCGCGCGCGTCTTCGACAACCAGGGTTTTTATTATTCCGGCGATGTCGTTCAGCGTACGCCCGAAGGTTACCT
GCGGGTGGTTGGCCGGGTGAAAGACCAGATCAATCGCGGCGGCGAGAAAGTCGCATCGGAAGAGGTGGAAAACCTGATCC
TGCGGCATCCGGATGTGACGCATGCCGCACTGGTGGCGATGCAGGACGAACTCCTCGGTGAAAAAAGCTGCGTCTTCGTC
GTTTCCCGCAATCCCGCTCTCAAGGCACCGACCATCCGCCAGCATCTCTCTGGTCTGGGTGTTGCGGATTACAAGCTGCC
GGATCGGGTGCGTTTCATCGACACCATACCGCTTACTGCCGTCGGCAAGATCGACAAGAAACGTCTGCGCGACATGCTCG
CAGCGCCAATCCCGGCGTAA

Protein sequence : 
MTIEFERWPEDLARRYRDRGYWIDRPLSDILTQQVELRPDATALICGDRRFTYADLDRQSSNLAGHLAAAGIGRGDTALV
QLPNIAEFYLVFFALMKIGAAPVNALFSHRRLEMTSYAEQIAPKLVIGSRSHELFANDTFLEALKLTSPRLAVTLLLGET
EPQRSLEQWLSSPAENAPHYGPSAADEVALFQLSGGSTGTPKLIPRTHNDYDYSARASAEICELTPQTRFLCAIPVAHNY
PMSSPGALGVFHAGGTVVMAANPEPLACFDLIEKHGIDIVPLVPPAVALWLQVAPAHRERLKSLKLLQVGGASFAEALAR
QVPQVLGCALQQVFGMAEGLVNYTRAGDPDHIVLTTQGRPISPDDEIRIVDEDGNDVPEGEAGMLATRGPYTFRGYYRAA
EHSARVFDNQGFYYSGDVVQRTPEGYLRVVGRVKDQINRGGEKVASEEVENLILRHPDVTHAALVAMQDELLGEKSCVFV
VSRNPALKAPTIRQHLSGLGVADYKLPDRVRFIDTIPLTAVGKIDKKRLRDMLAAPIPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-91 44
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-91 44
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-91 44
ybtE CAA21394.1 - Virulence HPI Protein 3e-91 44
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-91 44
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-91 44
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-91 44
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 3e-91 44
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-91 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AGROH133_13523 YP_004444533.1 2,3-dihydroxybenzoate-AMP ligase protein VFG0932 Protein 2e-155 57
AGROH133_13523 YP_004444533.1 2,3-dihydroxybenzoate-AMP ligase protein VFG0168 Protein 4e-112 46
AGROH133_13523 YP_004444533.1 2,3-dihydroxybenzoate-AMP ligase protein VFG1817 Protein 2e-88 41