Gene Information

Name : Poras_0502 (Poras_0502)
Accession : YP_004441624.1
Strain : Porphyromonas asaccharolytica DSM 20707
Genome accession: NC_015501
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 607323 - 608525 bp
Length : 1203 bp
Strand : -
Note : COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR006237; KEGG: pgn:PGN_1618 methionine gamma-lyase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Methionine gamma-lyase; SPTR: Methionine g

DNA sequence :
ATGATTGATCCAAAAAAACTACAGCAGATGGGCTTCGCTACGCGTGCCATCCATGCTGGTAGCGAGCGCAATCAGCACGG
TACGCTGGCTACACCTATTTATCAGACCTCTACTTTTGTTTTTGACTCTGCGGAGCAGGGTGGCAGACGCTTTGCCCTTG
AGGAGGACGGGTACATCTACACTCGTCTGGGGAATCCTACCTGCACAGCTGCTGAGCAGAAGGTTGCCTCTCTAGAGGGT
GGTGAGGCTTGCGTCAGCGCTTCTTCAGGCATTGGTGCGATCACCTCGGCTATCTACCCCTTGGTGCAGGCTGGTGACCA
CATCGTCGCAGGTAAGACGCTCTACGGCTGCACCTACTCATTCCTCGAGCATGGACTCTCACGCTTTGGTGTGGAGGTGA
CCTTCGTCGATGCGCGCAATCTTGATGAGATCAAGGCTGCTATGCGCCCCAATACGAAGCTGGTCTACATCGAGACCCCG
GCCAACCCTAACATGTACCTGACAGATATCGAAGGCGCTGCCAAGATAGCTCACAGCCAGGAGGGTACTGTGCTGATGGT
GGACAATACTTACTGCACGCCTTTTATCACGCGTCCTCTAGACCTCGGTGCTGATGTCGTAGTACACTCAGCTACGAAGT
ATCTGAATGGTCACGGTGATGTGATCGCCGGATTTGTCGTCGGTCGCAAGGAATATATCGACCAGGTGCGTCTCTTTGCT
GTAAAGGATATGACGGGATCAGTCCTAGGCCCGTTCGAAGCATACCTGATCGCTCGTGGTATCAAGACTCTGGAGATACG
TATGGAGCGTCACTGCGCTAATGCACAGCGTGTCGCTGAGTTCCTCGAGCAGCACCCCGCTATCGCCTCGATCGCTTACC
CAGGTCTCAAGAGCTTCCCACAGTATGAGCTAGCTCAGAAGCAGATGCGCCTACCAGGTGCTATGATCGCCTTCGAGCTC
AAGGGTGGTCTAGAGGCTGGTCGCAAGCTGATGAATAGCCTCCACCTAGCTACACTCTGCGTGAGCCTTGGTGATGCTGA
GACGCTTATCGAGCACCCAGCTAGCATGACTCACTCGCCCTACACACCTGAGGAGCGTGCTGCTTCTGACATTGGTGAGG
GTATGGTACGTCTCTCTATCGGTCTAGAGAATGTCGAGGACATCATCGCAGACCTTAAGTGTGGTCTAGACGCACTCCTA
TAA

Protein sequence :
MIDPKKLQQMGFATRAIHAGSERNQHGTLATPIYQTSTFVFDSAEQGGRRFALEEDGYIYTRLGNPTCTAAEQKVASLEG
GEACVSASSGIGAITSAIYPLVQAGDHIVAGKTLYGCTYSFLEHGLSRFGVEVTFVDARNLDEIKAAMRPNTKLVYIETP
ANPNMYLTDIEGAAKIAHSQEGTVLMVDNTYCTPFITRPLDLGADVVVHSATKYLNGHGDVIAGFVVGRKEYIDQVRLFA
VKDMTGSVLGPFEAYLIARGIKTLEIRMERHCANAQRVAEFLEQHPAIASIAYPGLKSFPQYELAQKQMRLPGAMIAFEL
KGGLEAGRKLMNSLHLATLCVSLGDAETLIEHPASMTHSPYTPEERAASDIGEGMVRLSIGLENVEDIIADLKCGLDALL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-60 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-61 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Poras_0502 YP_004441624.1 methionine gamma-lyase BAC0207 Protein 2e-106 57