Gene Information

Name : Poras_0977 (Poras_0977)
Accession : YP_004442088.1
Strain : Porphyromonas asaccharolytica DSM 20707
Genome accession: NC_015501
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1227515 - 1229035 bp
Length : 1521 bp
Strand : +
Note : COGs: COG0519 GMP synthase PP-ATPase domain/subunit; HAMAP: GMP synthase [glutamine-hydrolyzing]; InterPro IPR004739:IPR001674:IPR000991:IPR018318; KEGG: pgi:PG0589 GMP synthase; PFAM: GMP synthase, C-terminal; Glutamine amidotransferase class-I, C-termin

DNA sequence :
ATGCCGGACAAAATAATTATCGCAGACTTTGGGTCGCAGACTACACAGCTCATAGGTCGTCGTCTGAGAGACCTCAACAC
TTACTGCGAGATAGTCCCTTACAACAAGATCCCGACAGACCTGACGGGCGTCCGAGGCATCATCCTCTCGGGAAGCCCTT
ACTCGGTCTATGCTGAGGAGGCTTTTACCGCAGACATAGCAGCTATCCGTGGGCGGTTACCGATCTTGGGTATCTGCTAT
GGAGCGCAGTTGATGGTGCATCAGAATGGAGGCTCCGTGGAGAACTCCAATACCCGTGAGTACGGCGCCTCTACGCTACA
ACTGGTGGACAAGGGCGACCCGCTACTCGCAGGGCTTTCGCCACAGCACACGGTCTGGATGTCGCATGGTGACACGATCA
CCCGTCTTCCTGAGGGCTTTAAGGTGATCGCCTCGACTCCCTCGGTGCAGTATGCCGCTTATAGGATAGCGGGTGAGGAG
ACGTGGGGCGTACAGTTTCACCCAGAGATACATCACAGTGAGGAGGGTACGAAGCTCCTTGACAACTTTGTCACGCTCTG
TGGCATCAAGGGCGAGTGGTCGTCTGAGTCTTTCATCGAGAGCAGCATCGCCTCAATCAAGGCGCAGGTAGGTGACGAGC
AGGTCATCATGGCGCTCAGCGGAGGCGTGGACAGCTCGGTCGCAGCGGTCCTCCTACATCGTGCTATCGGCAATCAGCTC
ACCTGTATTTTTGTGGATCATGGCTTGATGCGACTAGGCGAGGCGGAGCAGATCTTGGCAGACTACAAGGCACTCGGACT
AGGCTGTATCAAGGTCGACGCGAGTGCGAAGTTCCTCGGAGATCTAGCTGGTGTTCGTGATCCCGAGGCTAAGCGTAAGG
TGATCGGTAGGGACTTCATCGAGGTCTTTGAGGCTGAAGCTAAGAAGCTTCCGCAGGCTCGTTGGCTGGGGCAGGGAACT
ATTTACCCAGACATCATCGAGTCTATTAACATCACGGGCAAGGTGATCAAGAGCCACCACAACGTGGGTGGACTGCCTGA
GCGTATGCACCTGAAGCTGGTGGAGCCGCTGAAGCATCTCTTTAAGGATGAGGTGCGTCGTGTTGGCTTGGCACTATCGA
TGCCACGACACATGATCTTTCGCCATCCCTTCCCAGGCCCGGGTCTAGGCATACGTGTCTTAGGCGAGGTGACTCCTGAG
AAGGTGGCTATCCTCCAGCAGGCTGACAAGATATACACCGACATGCTCCGCAAGTACAACCTCTACGACGAGGTGTGGCA
GGCGGGAGCTATCCTACTGCCGGTGCAGAGCGTAGGGGTCATGGGTGACGAGCGCACCTACGAGTACACGGTGGCACTAC
GGGCGGTGACGAGCGTCGATGCGATGAGCGCTGACTGGGCTCGGCTGCCGTACGACTTCCTCGCAGAGGTCTCTAACGAA
GTCATAAACAAGGTGCGTGGCGTCAATCGTGTCTGCTACGATGTGTCGTCAAAGCCACCCGCAACGATTGAGTGGGAGTA
A

Protein sequence :
MPDKIIIADFGSQTTQLIGRRLRDLNTYCEIVPYNKIPTDLTGVRGIILSGSPYSVYAEEAFTADIAAIRGRLPILGICY
GAQLMVHQNGGSVENSNTREYGASTLQLVDKGDPLLAGLSPQHTVWMSHGDTITRLPEGFKVIASTPSVQYAAYRIAGEE
TWGVQFHPEIHHSEEGTKLLDNFVTLCGIKGEWSSESFIESSIASIKAQVGDEQVIMALSGGVDSSVAAVLLHRAIGNQL
TCIFVDHGLMRLGEAEQILADYKALGLGCIKVDASAKFLGDLAGVRDPEAKRKVIGRDFIEVFEAEAKKLPQARWLGQGT
IYPDIIESINITGKVIKSHHNVGGLPERMHLKLVEPLKHLFKDEVRRVGLALSMPRHMIFRHPFPGPGLGIRVLGEVTPE
KVAILQQADKIYTDMLRKYNLYDEVWQAGAILLPVQSVGVMGDERTYEYTVALRAVTSVDAMSADWARLPYDFLAEVSNE
VINKVRGVNRVCYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-120 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-120 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-120 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-102 48