Gene Information

Name : Trebr_0803 (Trebr_0803)
Accession : YP_004439370.1
Strain : Treponema brennaborense DSM 12168
Genome accession: NC_015500
Putative virulence/resistance : Resistance
Product : two component transcriptional regulator, winged helix family
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 985366 - 986067 bp
Length : 702 bp
Strand : -
Note : COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: ssm:Spirs_2695 two component transcriptional regulator, winged helix family; PFAM: Signal transduction r

DNA sequence :
ATGTCCTGCATCATGCTTGTTGAAGACAACACGCTCATACGCGAGGCCGTCGCCGGTTACCTGCAGCTTGACGGACACAA
AACGGTAGAATTCGATACCGGAGCGGGTGTACTGGACGCAGTACGGCGGGAAATAGCCGATCTGATCATTTTGGACGTCA
TGCTTCCCGACGGAAACGGATTTGCCCTTGCAAAATCGATACGCGCAGTCTCGGCAGTACCGATCATTTTTTTAACGGCA
AAAGACAGCGAATCGGACCGAATTTTGGGCTTTGAACTGGGTGCGGACGATTACATCTGCAAACCGTTTTCCGCCAAAGA
ACTGGTACTCCGCGTACAGGCGCTGCTCAGACGCAGCGGCGGCAGTGCCGAAACGGTTCCCGGAGCTTCGGGCGAATGGC
AGCAAGGCGAAAGCCGCGCAACGCTTGACACGGCGAAACACACGCTGGCTATAGACGGAATCGACGTAAATCTGACCGGC
GCGGAATGGAAAATCCTCGTCTATCTCGCAGAAAACAGCGGCCAAGTCGTTTCCCGCGAACAGATATTGTCCGAATGCTT
CAATTATTTTTTTGAAGGATCCGAACGCACCGTCGATACGCACATCGCCAACTTACGGGCAAAACTCGGCGTGGGCTGGA
TAGTTACCGTCAGGGGCTTCGGCTACAAATTCGGCGGCAGTCTCCGATCGGAGTCCGCATGA

Protein sequence :
MSCIMLVEDNTLIREAVAGYLQLDGHKTVEFDTGAGVLDAVRREIADLIILDVMLPDGNGFALAKSIRAVSAVPIIFLTA
KDSESDRILGFELGADDYICKPFSAKELVLRVQALLRRSGGSAETVPGASGEWQQGESRATLDTAKHTLAIDGIDVNLTG
AEWKILVYLAENSGQVVSREQILSECFNYFFEGSERTVDTHIANLRAKLGVGWIVTVRGFGYKFGGSLRSESA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CDB402_0209 YP_005126722.1 two-component system response regulator Not tested Not named Protein 1e-21 41
mprA YP_005680459.1 response regulator mprA Not tested PiCp 3 Protein 4e-23 41
mprA YP_005682550.1 response regulator mprA Not tested PiCp 3 Protein 4e-23 41
tcsR1 YP_003782583.1 two-component system transcriptional regulatory protein Not tested PiCp 3 Protein 4e-23 41
mprA YP_005684640.1 response regulator mprA Not tested PiCp 3 Protein 4e-23 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Trebr_0803 YP_004439370.1 two component transcriptional regulator, winged helix family NC_002952.2859905.p0 Protein 6e-31 44
Trebr_0803 YP_004439370.1 two component transcriptional regulator, winged helix family NC_007622.3794472.p0 Protein 6e-31 44
Trebr_0803 YP_004439370.1 two component transcriptional regulator, winged helix family NC_002745.1124361.p0 Protein 7e-31 44
Trebr_0803 YP_004439370.1 two component transcriptional regulator, winged helix family NC_009782.5559369.p0 Protein 7e-31 44
Trebr_0803 YP_004439370.1 two component transcriptional regulator, winged helix family NC_002951.3237708.p0 Protein 7e-31 44
Trebr_0803 YP_004439370.1 two component transcriptional regulator, winged helix family NC_002758.1121668.p0 Protein 7e-31 44
Trebr_0803 YP_004439370.1 two component transcriptional regulator, winged helix family NC_003923.1003749.p0 Protein 6e-31 44
Trebr_0803 YP_004439370.1 two component transcriptional regulator, winged helix family NC_009641.5332272.p0 Protein 7e-31 44
Trebr_0803 YP_004439370.1 two component transcriptional regulator, winged helix family NC_013450.8614421.p0 Protein 7e-31 44
Trebr_0803 YP_004439370.1 two component transcriptional regulator, winged helix family NC_007793.3914279.p0 Protein 7e-31 44
Trebr_0803 YP_004439370.1 two component transcriptional regulator, winged helix family CP001918.1.gene5135. Protein 4e-26 42