Gene Information

Name : Trebr_0344 (Trebr_0344)
Accession : YP_004438922.1
Strain : Treponema brennaborense DSM 12168
Genome accession: NC_015500
Putative virulence/resistance : Virulence
Product : ParB domain-containing protein nuclease
Function : -
COG functional category : K : Transcription
COG ID : COG1475
EC number : -
Position : 397062 - 397598 bp
Length : 537 bp
Strand : +
Note : COGs: COG1475 transcriptional regulator protein; InterPro IPR003115; KEGG: cdl:CDR20291_0520 hypothetical protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: uncharacterized protein; IMG reference gene:2504919209; PFAM: ParB-like nuclease

DNA sequence : 
ATGGAATTTAAAAGTCCTGTTTATCAGGTGATTTCAGTGCCGATAGAAAAAATAACGGCGAATACGTATAATCCGAACAG
CGTCGCCCCTCCTGAAATGGATCTGCTGTACGACAGCATAAAAGAAGACGGCTACACGCAGCCTATCGTGTGCTATTATT
CCGTGCCGGACGATACGTACATTATTGTTGACGGCTTTCATCGTTATCGCATTATGATGGAGCACCGTGACATTTATCAG
CGTGAGCAAGGAAAATTGCCGGTGGTAGTGATCGATAAAGCGCTTGATCATCGTATGGCAAGTACGATTCGGCACAACAG
AGCACGCGGTTCCCACGATGTGGATCTGATGAGCAACATCGTCAAGGAATTGCATGACATAGGCCGCAGCGATGCCTGGA
TTTCAAAGCATCTCGGAATGGATCGCGATGAAATCCTCCGGCTGAAACAAATTACCGGACTTGCGGCGCTGTTTCGGGAT
ACGGAATTCGGCAACGCTTGGGTACCGGAAGACGAAGAGCTGGACGGAGAGTTGTAA

Protein sequence : 
MEFKSPVYQVISVPIEKITANTYNPNSVAPPEMDLLYDSIKEDGYTQPIVCYYSVPDDTYIIVDGFHRYRIMMEHRDIYQ
REQGKLPVVVIDKALDHRMASTIRHNRARGSHDVDLMSNIVKELHDIGRSDAWISKHLGMDRDEILRLKQITGLAALFRD
TEFGNAWVPEDEELDGEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
M5005_Spy_0164 YP_281528.1 parB-like nuclease Not tested Not named Protein 2e-63 75
ef0120 AAM75321.1 EF0120 Not tested Not named Protein 4e-39 57
EF0607 NP_814365.1 ParB-like nuclease domain-containing protein Not tested Not named Protein 6e-39 57
STY4584 NP_458668.1 conserved hypothetical protein Not tested SPI-7 Protein 5e-31 48
t4278 NP_807876.2 hypothetical protein Not tested SPI-7 Protein 5e-31 48
Z1644 AAQ19140.1 putative ParB-like nuclease Not tested PAI I CL3 Protein 6e-31 46
ibrB ADD91736.1 predicted transcriptional regulator IbrB Not tested PAI-I AL862 Protein 6e-31 46
Z1204 NP_286739.1 hypothetical protein Not tested TAI Protein 1e-30 46
Z1644 NP_287147.1 hypothetical protein Not tested TAI Protein 1e-30 46
z1204 CAD33764.1 Z1204 protein Not tested PAI I 536 Protein 2e-30 45
ORF_30 AAZ04440.1 conserved hypothetical protein Not tested PAI I APEC-O1 Protein 8e-19 44
APECO1_3503 YP_854305.1 hypothetical protein Not tested PAI I APEC-O1 Protein 1e-18 44
c5208 NP_757056.1 hypothetical protein Not tested PAI II CFT073 Protein 1e-18 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Trebr_0344 YP_004438922.1 ParB domain-containing protein nuclease VFG1505 Protein 8e-31 45