Gene Information

Name : Trebr_1118 (Trebr_1118)
Accession : YP_004439681.1
Strain : Treponema brennaborense DSM 12168
Genome accession: NC_015500
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1331440 - 1333242 bp
Length : 1803 bp
Strand : -
Note : COGs: COG0469 Pyruvate kinase; InterPro IPR001697:IPR015793:IPR015794; KEGG: ssm:Spirs_0059 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; IMG reference

DNA sequence :
ATGTTTTCCAGAAAGACCAAAATCGTCTGCTCGATGGGTCCCACCACTGCCGACGACAGTATAATAGAACAATTAGTGCA
GGCCGGCATGAATATTGCCCGTTTCAATTTTTCGCACGGAACACACGATACGCACAAAGAAGCAATGGATCGGGTAAAGC
GGGTATCCGCAAAATTGAAAATACCCGTCGCGCTGCTGCTTGACACGAAAGGGCCCGAAATCCGTACCGGCATGACGGCC
GGCGGCGGAACGGTTACGATCCGCACCGGCGACACGATTCTGATTACCGTCGACGGGCAGGAAACGACGGCGGCAACTGA
ATCGCAGCCGGCACGGCTTTCCGTAACCTGGACGGCACTCCCTGAAAAAGCCGTTCCCGGCGTCCGTATACTCATTGCCG
ACGGTCTCTTGGAACTCGACGTTACCGAAGTTACCGGCAAAACGGTGCGGTGCGTCGCGCGTAATACCGGCAGCATCGGA
AGCCGGAAAAACGTCAATCTTATCGGCATACACGCGGGGCTTCCGATCATAAACGATCAGGATAAAAGCGACCTCGCGTT
CGGCGCCGAACAGGGAATCGATTTCGTCGCCGCAAGTTTCGTCAGTTTTGCATCCGAAGTAAACGAAATCCGCCGGTACC
TTGAATCAATCAACAGCCGCGCAAAAATAATCGCCAAGATCGAAAACGAAGAAGGGCTCAATAATATAGAAGAAATCGTT
AAAGCGGCGGACGGTGTCATGGTAGCCCGCGGCGATTTGGGCGTACAGCTGCCCACCGAACGGATTCCGCTCGCCCAAAA
ACATATTATCGAAATATGCCGCCGATCGGGCAAACCCGTCATCACGGCGACTCAAATGCTCGACTCCATGATCGTCAATC
CGCGTCCCACTCGTGCCGAACTGACCGACGTGGCGAACGCCATCTTCGACGGTACCGACGCCGTCATGCTTTCAGGAGAA
ACGGCGAACGGCGCCTATCCGGTGGAAGCCGTAAAGACGATGGCGCGCATCGCCGTTACCGTTGAAGATTCCGCGGAATT
CTGCAGGAAAATGAATACGGAAGACATGTCCGACGAATACTATCCGATCGGCAACATCGGTCTCATAATGGCCAGAAACG
CTTATACCACCGCGCGCGACGTAAAAGCGATGGTCATCATTGCGCCGACTCTTTCGGGGCACACCGCTCATATGATAAGC
AAATACCGCCCGGAACAAGCCGTCATCGCGGTAACGCCGGATCCCGTCGTAGCGCGCCAGCTGCTGCTGTACTGGGGCGT
CGTACCGCTCCATACGAAACGCGCGGACGACTCGAACGAAATGATTCAAAACGCTGTAAAAACGGCGCTCGACGCCGGCG
CTATCCATATCTCAGACCGAATCGTATTGGCGGCCGGCGTACCGCTGTTCAGCCCGCTCATGCTGAACACGGTGCGCGTA
CTGATGGTGGGCAACGTACTCGCTCGCGGTTTATCCGGCGGCAGCGCCGATCCTGAAAAACCGAAAGCATCCGGCCGCAT
CGTGCGCGCCGCAACTCCCGGCGAAGCGCGGGGTCTGCTCAAACATCACGGCGGCGAAATTCTGGTCTGCCGGAACATCA
CGCAGGAATACATACCGATACTGCGCATAGTAAACGGTGTTATCGCCGAACACGGTTCAGAACTTTCGGAACAGATTCTG
GCTATGGTCAATCCGAATCTGGTTTGGCTTACGAGCGTAGCCGGCGCCACGACGACGCTCGAATCGGGACTCGTCGTCAC
TATCGACGGTACACAGCTGCTCGTATACGAAGGTACTATTTAA

Protein sequence :
MFSRKTKIVCSMGPTTADDSIIEQLVQAGMNIARFNFSHGTHDTHKEAMDRVKRVSAKLKIPVALLLDTKGPEIRTGMTA
GGGTVTIRTGDTILITVDGQETTAATESQPARLSVTWTALPEKAVPGVRILIADGLLELDVTEVTGKTVRCVARNTGSIG
SRKNVNLIGIHAGLPIINDQDKSDLAFGAEQGIDFVAASFVSFASEVNEIRRYLESINSRAKIIAKIENEEGLNNIEEIV
KAADGVMVARGDLGVQLPTERIPLAQKHIIEICRRSGKPVITATQMLDSMIVNPRPTRAELTDVANAIFDGTDAVMLSGE
TANGAYPVEAVKTMARIAVTVEDSAEFCRKMNTEDMSDEYYPIGNIGLIMARNAYTTARDVKAMVIIAPTLSGHTAHMIS
KYRPEQAVIAVTPDPVVARQLLLYWGVVPLHTKRADDSNEMIQNAVKTALDAGAIHISDRIVLAAGVPLFSPLMLNTVRV
LMVGNVLARGLSGGSADPEKPKASGRIVRAATPGEARGLLKHHGGEILVCRNITQEYIPILRIVNGVIAEHGSELSEQIL
AMVNPNLVWLTSVAGATTTLESGLVVTIDGTQLLVYEGTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-74 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-75 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-74 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-74 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Trebr_1118 YP_004439681.1 pyruvate kinase VFG0479 Protein 8e-75 44