Gene Information

Name : Trebr_0998 (Trebr_0998)
Accession : YP_004439565.1
Strain : Treponema brennaborense DSM 12168
Genome accession: NC_015500
Putative virulence/resistance : Virulence
Product : ATPase AAA-2 domain-containing protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1198549 - 1201131 bp
Length : 2583 bp
Strand : +
Note : COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR004176:IPR003959:IPR001943:IPR 013093:IPR019489; KEGG: ssm:Spirs_1928 ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities, AAA-2; ATPa

DNA sequence :
ATGATGAAGAGTTTGTCTCCACGCGCGCAGAAACTGATAGCCGTTTTTGCTCAGGACGAAGGACGTAAAAGCGGAAGCGA
ACAGCTGCTGCCGGAACACGTATTGCTCGGTCTGCTCAAAAGTGCGGACGGATTGGGATATATTTTGTTGCAGCAGCTGC
ACATCAACGTGCTGACGTTTCAGCTGGCCCTCGAACAGAGTTTGACGCAGCGGACGACGAGCCGTTCGTTCACCGATTTG
CCGCCGTCGCGCCGCGTGCGGACGCTGCTCGATGCGGCTTCCGTCGAGTCGCGGACTTTCAGCCGCGAATACGTGGGAAC
CGAACACTTGGTTGTTGCGGCGGTGCGTGAAGAGTACAGCATTACCGCGATGTATTTTGAGAAAGCCGGAATTTCACTGG
AGGCAATGCACGCGGCGCTGGGAGAAGTGTACAATCGCTTCCAATCGTCGTTCGACGTTCAGAAAATAAAAAACGCCGCC
GGCGCGGTTTTCGCCTCGCTCGACCAGCAGGCAAAAAAGCAGGCGAAGCCGGGCAAAGCTCCCGTTCAGTCGGTTTTGGC
GGAATTCAGCCGCGATTTGACGGCGCTTGCCCGGGATAAGGCGCTTGACCCGGTGGTCGGCCGCGACAAGGAGATCCGCC
GCGTGATACAAATCCTTTCACGCCGGACCAAAAACAATCCGGTGCTGATCGGTGAACCGGGCGTCGGCAAAACGGCGATC
GTTGAAGGCCTCGCGCAGCAGATTGCGGCGGGACAAGTGCCCTTCGGCTTGCTGAAAAAACGGATCGTTTCGCTGGATCT
TGCGTCCGTCATTGCCGGAACGAAATACCGCGGCGAATTTGAAGAACGTATCAAACGTATTCTGAAAGAAATATATGAAA
GCAAAGACGTTATCCTGTTCATAGACGAACTGCACACCGTCGTGGGAGCCGGCAGCGCGGAGGGCACGATGGACGCGTCC
AACATGCTGAAGCCGGCGCTGGCCCGAGGCGAATTGCAGTGCGTCGGTGCGACGACGATCAGCGAATACCGCAAATATTT
TGAAAAAGACGCCGCGCTTGAACGCCGTTTTCAGTCGGTTCTGGTTTCCGAACCCACCGATGCGGAAACGGAACGGATTC
TGGAGGGGCTGAAGCCGAAATATGAACAATACCACGGCGTGTCGTACGGCGCCGAGGTCATACGGGCTGCGGTTCGTTTT
TCACGCCGATATTTGACCGAACGGTGTCTGCCGGATAAAGCGATCGATATTTTGGATGAAGCCGGCGCCATGAAAAAAAT
CAACGAAGAAGAGCGCCCGGCGGAGCTTGCCGAATTGGAACACAGCATCGAACTGCTTACGGAAGAAAAAAAACAGTTGG
TGCAGAATCAGGATTACGAGCGTGCCGCCGAAGTGCGCGATAAAGTTCATTTGCTGAGAGAAAAGCTGGAACAATTCCGT
TCGGCTTGGGAAAGCGGTACGGAACGGAAGGCGAAAAGCGTTACCGTACAGGACGTCTGTTCGGTCATAGCCGATATGAC
CGGTATTCCTTCCGAACAGCTGAGCGAATCTGAAAGTTCGCGGCTGCTGCACATGGAAGACGAACTGCATAAAACGATCG
TCGGTCAGAACGAAGCGGTGGCGCGCATCGCCTCCGCGGTTCGCCGGTCCCGTGCGGGCGTTTCGTCTTCAAAACGGCCC
GCCGGCTCGTTTATCTTTTTGGGGCCGACCGGCGTCGGAAAAACGCTGCTGGCAAAAACGCTCGCTCGCTTTCTGTTCGG
TTCTGACGAAGCGCTCATCAGAATCGATATGAGCGATTTTATGGAAAAACACAACGCGAGCCGGCTTGTCGGCGCGCCGC
CCGGATACGTCGGTTTTGAAGAAGGCGGTCTGCTGACTGAAAAAGTCCGCCGCCGCCCGTATTCGGTCGTGCTGCTTGAT
GAAATAGAAAAAGCGCACCCCGACGTGTTCAATTTGCTGCTGCAGGTTTTGGAAGAAGGGGAACTTTCCGACAGCCTGGG
GCATACCGTCAATTTCCGCAACACGGTTATCATCATGACGAGCAACGCCGGCGTCCGTGACATTACGAACGGCAACAGAC
TCGGTTTCGCCGTAAACGACGGCGGACAGCTGTCCTATGAAGCGATAAAAAGCGGCGCGCTCTCCGAATTGAAAAAACTG
CTGAGCCCCGAGCTGATAAACCGCATCGACGATATTATGGTGTTCAACGCGCTTTCCCGTGCCGAAGTCGCCTCGATTTT
GGATATACAGCTGTCGGAACTTTCCGAGCGGCTTTGCGAACAGCACGTGTCGCTGACGGTAAAACCGGCGGCGCGCGATT
ATCTGATAGACCACGGGTACGACCCGGCGTTCGGCGCGCGCCCGATGCGCCGTCTGATTCAGCGTGAGATTGAAGATCCG
CTCGCGCTCCGGCTGCTGGAAAGCGCCTCCGATGCGGCCGCTTCGGGTCAAAGCGGCGCCGCGGCTTCGGTGGATTACCG
TAACGGTGCCGTCAAGGTAACGCTGAAACGGAAACGGCTTGCCGTTCCGCCCGCCGTTACACCGGAGCAATTGCCCGCGC
CCGATTCGGTCGAGTCGCGGTAA

Protein sequence :
MMKSLSPRAQKLIAVFAQDEGRKSGSEQLLPEHVLLGLLKSADGLGYILLQQLHINVLTFQLALEQSLTQRTTSRSFTDL
PPSRRVRTLLDAASVESRTFSREYVGTEHLVVAAVREEYSITAMYFEKAGISLEAMHAALGEVYNRFQSSFDVQKIKNAA
GAVFASLDQQAKKQAKPGKAPVQSVLAEFSRDLTALARDKALDPVVGRDKEIRRVIQILSRRTKNNPVLIGEPGVGKTAI
VEGLAQQIAAGQVPFGLLKKRIVSLDLASVIAGTKYRGEFEERIKRILKEIYESKDVILFIDELHTVVGAGSAEGTMDAS
NMLKPALARGELQCVGATTISEYRKYFEKDAALERRFQSVLVSEPTDAETERILEGLKPKYEQYHGVSYGAEVIRAAVRF
SRRYLTERCLPDKAIDILDEAGAMKKINEEERPAELAELEHSIELLTEEKKQLVQNQDYERAAEVRDKVHLLREKLEQFR
SAWESGTERKAKSVTVQDVCSVIADMTGIPSEQLSESESSRLLHMEDELHKTIVGQNEAVARIASAVRRSRAGVSSSKRP
AGSFIFLGPTGVGKTLLAKTLARFLFGSDEALIRIDMSDFMEKHNASRLVGAPPGYVGFEEGGLLTEKVRRRPYSVVLLD
EIEKAHPDVFNLLLQVLEEGELSDSLGHTVNFRNTVIIMTSNAGVRDITNGNRLGFAVNDGGQLSYEAIKSGALSELKKL
LSPELINRIDDIMVFNALSRAEVASILDIQLSELSERLCEQHVSLTVKPAARDYLIDHGYDPAFGARPMRRLIQREIEDP
LALRLLESASDAAASGQSGAAASVDYRNGAVKVTLKRKRLAVPPAVTPEQLPAPDSVESR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-152 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Trebr_0998 YP_004439565.1 ATPase AAA-2 domain-containing protein VFG0080 Protein 6e-143 53
Trebr_0998 YP_004439565.1 ATPase AAA-2 domain-containing protein VFG0079 Protein 1e-164 47