Gene Information

Name : Thena_0877 (Thena_0877)
Accession : YP_004437637.1
Strain : Thermodesulfobium narugense DSM 14796
Genome accession: NC_015499
Putative virulence/resistance : Virulence
Product : Aldehyde Dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 872472 - 873953 bp
Length : 1482 bp
Strand : -
Note : COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: ssm:Spirs_2638 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; SPTR: Aldehyde dehydrogenase (NAD+); IMG reference gene:2504784270; PFAM: Aldehyde dehydrogenase

DNA sequence :
ATGAAAAAGAACGATTATGTTGACAAAAGTTATAAGCTTTATATTGATGGTAAATGGGTGGATGCCGTTGATGGGAAAAC
TTTTGAAGTATTTTGTCCGGCAGATGGAGAAAAAATTTCTATCTGTGCCGACGCTGGAAAAGAGGATGTCGACCTTGCAG
TAAAAGCAGCGCATAAAGCTTTTTGCTCATGGAAAAATGTTAGCGCACAAGAAAGAGCTTCTATACTTCTAAAAATCGCC
GATTTAATTGACAAAAATGCTGATAGACTTGCAATGGCAGAAACAATTGACAATGGCAAACCAATAAGAGAAACATCTGC
TATAGATGTACCACTTAGCTCAGATCATTTTCGCTATTTTGCAAGCGCAATCAGGACTGAAGAAGGAAAAGCTGTAATGA
TAGATAAAAACACCATGAGTATTATTTTGAATGAACCTTTGGGAGTTGTTGGCCAGATTACGCCATGGAATTTCCCATTG
TTAATGGCGGCATGGAAATTAGCACCTGCTCTTGCAGCTGGAAATTGTGTTGTGCTCAAACCTTCTTCACTAACTCCAAT
AAGCACTTTAGAGCTGGCTAAATTACTCGATCAGGTTTTACCTCCCGGTGTCGTAAACGTATTATCCGGTAAAGGTTCAT
ATACTGGAAAGTGTATATTAGAGCATCAAGGATTTAACAAGCTAGCTTTTACTGGCTCTACAGAAGTGGGTTATTCTATA
GCCGAAGCAGCAGCAAAAAAATTGATTCCTTCTACATTGGAACTAGGAGGAAAATCAGCAAATATATTTTTTGATGATTG
TTCATGGGATAAAGCTATTGAAGGCTTGCTTATTGGAATCTTATTCAATCAAGGTCAGGTTTGCTGTGCTGGTTCACGAG
TATTTGTTCAGGAAAAGATATATGATAAATTCCTTGCTGAGGCAATAAAATCATTCGAAAAAGTTAAAGTAGGTATCCCG
TGGGAAAAAGACACTCAGATGGGAACATTAATCAGCTCAGTCCAATTAGAAAAGGTTTTGGCATATATTAATATTGGTCA
TAAAGAAGGCGCAAAAATAGCATGTGGTGGACAAAGAATTACTGATAATGGACTAGATAAAGGCTTCTTCATCAAACCAA
CAATCCTTGCAGATGTTAGCAATAAGGCACGAGTAGCGCAAGAAGAAATTTTCGGACCCGTTGCGTGTTTTATAAAATTT
AATAGCGAAGAAGAAGTCATTCAAATGGCTAATGATAGCGAATATGGATTGGGGGGAGCTGTTTGGACGAAAGATATTAA
TAGAGCCTTAAGGGTTGCCAGAGCCGTTGAAACCGGACGTATGTGGATTAACAATTACAACAACCTCCCAGCACATGCCC
CATTTGGAGGATACAAAAAATCAGGAATAGGGAGAGAGACACACAAACTGGTGCTTGAACATTATACGCAAAAGAAAAAC
ATATTTATAAGCCTTTCAGATGACAAAGTTGGACTATATTAA

Protein sequence :
MKKNDYVDKSYKLYIDGKWVDAVDGKTFEVFCPADGEKISICADAGKEDVDLAVKAAHKAFCSWKNVSAQERASILLKIA
DLIDKNADRLAMAETIDNGKPIRETSAIDVPLSSDHFRYFASAIRTEEGKAVMIDKNTMSIILNEPLGVVGQITPWNFPL
LMAAWKLAPALAAGNCVVLKPSSLTPISTLELAKLLDQVLPPGVVNVLSGKGSYTGKCILEHQGFNKLAFTGSTEVGYSI
AEAAAKKLIPSTLELGGKSANIFFDDCSWDKAIEGLLIGILFNQGQVCCAGSRVFVQEKIYDKFLAEAIKSFEKVKVGIP
WEKDTQMGTLISSVQLEKVLAYINIGHKEGAKIACGGQRITDNGLDKGFFIKPTILADVSNKARVAQEEIFGPVACFIKF
NSEEEVIQMANDSEYGLGGAVWTKDINRALRVARAVETGRMWINNYNNLPAHAPFGGYKKSGIGRETHKLVLEHYTQKKN
IFISLSDDKVGLY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-97 52
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-101 51
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-101 51
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-101 51
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-100 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thena_0877 YP_004437637.1 Aldehyde Dehydrogenase VFG0082 Protein 3e-97 52