Gene Information

Name : Thena_1219 (Thena_1219)
Accession : YP_004437969.1
Strain : Thermodesulfobium narugense DSM 14796
Genome accession: NC_015499
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1256066 - 1257817 bp
Length : 1752 bp
Strand : -
Note : COGs: COG0469 Pyruvate kinase; InterPro IPR001697:IPR015793:IPR015794:IPR008279; KEGG: tjr:TherJR_2325 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region; PRIAM: Pyruvate kinase., Pyruvate, wat

DNA sequence :
ATGCTTAGAAAAACTAAAATAATATGCACTTTGGGGCCTAGCACAGACGATCCTGAAATTTTATATAAATTTGTTGAAAA
CGGAATGGATGTCGCTAGGTTTAATTTTTCTCATGGAGATTATGAGGATCATTTTAGAAGAATCCAAATGGTAAGAGAGG
CTTCAAAAAAGCTAAAAAAGGAAGTAGCCTTGATGCTAGATACCAAGGGTCCTGAAATCAGAGTTGGTAAGTTTAAAAGT
GGATCTGTACAGCTTAGAAAAGGGCAAAAATTTACTTTAACTGCTGAAGAAATTGAGGGAAATGAAGGAATTGTTTCTGT
TACTTATCCTGATCTGGTAAAAAAAGTAAAAAAGAATAACGTAATAGTTTTATCAGATGGATTGATTTCGTTACTTGTTG
ATGGTGCTGATGATAAAAATATCTATACTACAGTAATGAATAATGGGATTTTAAAAGACCATAAAAGAGTAGCTGTGCCC
GGAATTTTTTTGGACATGAATTTTTTGTCCGAAAAGGACATAAACGATATAAAATTTGGAATTGAAAACGAAATGGACTT
TATTGCTGCTTCCTTTGTCCAAAATGCGTCAAATATATTAGAGATTAGAAGAGTTTTAGAAGAAAATGATTCGAATATGG
ATATTATTGCAAAAATAGAGAATAGATTTGGGATTGAAAACATCGATGAAATTCTTAAAGTTGCTGATGGTATTATGGTG
GCAAGAGGCGATATGGGAATTGAGATACCAAATGAAGATGTTCCATTAATTCAAAAGGAGTTAATCAAAAAAGCTAACAA
GGTTGGAAAACCAGTAATAACTGCTACGCAAATGCTTGAATCAATGATAAACAATCCTCATCCTACTAGAGCCGAAGCAA
GCGATGTAGCAAACGCTATTCTGGATGGTACAGATGCAGTGATGCTTAGTGGTGAAACAGCTGCTGGAAACTATCCTTTG
GAAGCAATGGAAATGATGACAAGAATTGCATTAAAAACCGAAATGTCATTAGATTACAAGGCAATATTTTTGTCAAAGGG
TCTGAACCAGAAGACTACTACTGATGCTATTAGCCATGCTACAGTCCAAATTTCTCATGAGCTTGATGCTGCCGCGATTG
TAAGCATTACTCAAAGCGGATATACTGCTAAGATGGTTTCAAAATATAGACCAAATGCTTTTATTGTGGGCGTTTCTCCT
GACATTAGGATGGTTAGAAAGATGAAGTTAGTTTGGGGGGTTTATCCTATAAAATGTGAAAAAACTAACAACATTGAAGA
AATGGTTTTGGAGGCAATTAGCAAGTCTAGTGCTTCTAATTTAATTAAAGAGGGCGATTTGATAGTAATTACTGCAGGCG
TACCATTGGGTACTACAGGTACTACAAATATGATAAGAGTTCATTTGGTTGGCAATATTATCCTGAGAGGAATTGGTGTT
GGACATAGTTCATATACAGGGACAGTTTGTGTTGCTAGTACTTTGAAGGATTTTAAAGAAAAGATGAAAGCTGGGTGCAT
TGTAGTTGCAAAAAGTATTGATGAAGAGTTAGCTAAATATACTACAGAAGCTGGGGCGCTAATAGTGGAAGAAGGAGGGC
TTACTTCAAATGCTGTAATACTTGGAATAAATTTTGGTATTCCTGTTGTAATCGGTGTAGAAGGAGCTGTTGAGCTTCTA
AAAGATGGCCTAGTAGTTACAGTTGATGCAGAGAAGGGATTAATTTATCAAGGAGAAATAAACGTTAGATAG

Protein sequence :
MLRKTKIICTLGPSTDDPEILYKFVENGMDVARFNFSHGDYEDHFRRIQMVREASKKLKKEVALMLDTKGPEIRVGKFKS
GSVQLRKGQKFTLTAEEIEGNEGIVSVTYPDLVKKVKKNNVIVLSDGLISLLVDGADDKNIYTTVMNNGILKDHKRVAVP
GIFLDMNFLSEKDINDIKFGIENEMDFIAASFVQNASNILEIRRVLEENDSNMDIIAKIENRFGIENIDEILKVADGIMV
ARGDMGIEIPNEDVPLIQKELIKKANKVGKPVITATQMLESMINNPHPTRAEASDVANAILDGTDAVMLSGETAAGNYPL
EAMEMMTRIALKTEMSLDYKAIFLSKGLNQKTTTDAISHATVQISHELDAAAIVSITQSGYTAKMVSKYRPNAFIVGVSP
DIRMVRKMKLVWGVYPIKCEKTNNIEEMVLEAISKSSASNLIKEGDLIVITAGVPLGTTGTTNMIRVHLVGNIILRGIGV
GHSSYTGTVCVASTLKDFKEKMKAGCIVVAKSIDEELAKYTTEAGALIVEEGGLTSNAVILGINFGIPVVIGVEGAVELL
KDGLVVTVDAEKGLIYQGEINVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-85 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-85 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 9e-85 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-85 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thena_1219 YP_004437969.1 pyruvate kinase VFG0479 Protein 2e-85 44