Gene Information

Name : Glaag_4444 (Glaag_4444)
Accession : YP_004436624.1
Strain :
Genome accession: NC_015498
Putative virulence/resistance : Virulence
Product : two component heavy metal response transcriptional regulator, winged helix family
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 175806 - 176492 bp
Length : 687 bp
Strand : -
Note : TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; KEGG: pha:PSHAb0012 transcriptional activator of copper resistance (two-component regulatory system with CusS); SMART: respons

DNA sequence : 
ATGCGTTTACTGATTGTTGAAGATGAAACAAAAACAGGTGACTATTTAAAACAAGGCTTAAGCGAAGCGGGTTTTCAAGT
GTCTTTAGCGCGTAACGGTCTTGATGGTCATCACTTTGCTATGACTGAGTCCTTTGAAGTGATTATTTTAGATGTGATGT
TGCCTGATGTGTCAGGTTGGCGAATTTTAGAATCCCTGCGGGAAGCCAATAATGACACGCCTGTGCTGTTTTTATCTGCC
CGCGACAGTGTAGACGATAGAGTAAAAGGCCTAGAGCTAGGCGCTGATGACTACTTAGTCAAACCTTTTGCTTTTTCTGA
AGTATTAGCCAGAGTACGCACCCTTATTCGTCGTGGTGGTGCGCAAAAAGTGGAAGACACCTTTAAAGTGGCTGACTTAG
AAATGTCTATCCCGCAGCGTAAAGTCACCCGTACAGGAAAACGTATTTTACTCAGCAATAAAGAATTTAGTTTACTTGAG
CTTTTGTTGCGCCGTGAAGGTGAAGTGTTACCGCGATCGCTCATAGCCTCGCAAGTTTGGGACATGAATTTTGACAGTGA
TACTAACGTTATTGATGTGGCAATCAGACGGTTAAGGGGCAAAGTTGACGATGAGTTTGGCCTAAAGCTGATCCATACTG
TACGGGGCATGGGTTATAAATTAGAGGTTGAAACCGATGAAAGCTAA

Protein sequence : 
MRLLIVEDETKTGDYLKQGLSEAGFQVSLARNGLDGHHFAMTESFEVIILDVMLPDVSGWRILESLREANNDTPVLFLSA
RDSVDDRVKGLELGADDYLVKPFAFSEVLARVRTLIRRGGAQKVEDTFKVADLEMSIPQRKVTRTGKRILLSNKEFSLLE
LLLRREGEVLPRSLIASQVWDMNFDSDTNVIDVAIRRLRGKVDDEFGLKLIHTVRGMGYKLEVETDES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-49 54
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 4e-49 53

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Glaag_4444 YP_004436624.1 two component heavy metal response transcriptional regulator, winged helix family BAC0111 Protein 1e-64 67
Glaag_4444 YP_004436624.1 two component heavy metal response transcriptional regulator, winged helix family BAC0197 Protein 3e-55 63
Glaag_4444 YP_004436624.1 two component heavy metal response transcriptional regulator, winged helix family BAC0083 Protein 3e-60 63
Glaag_4444 YP_004436624.1 two component heavy metal response transcriptional regulator, winged helix family BAC0638 Protein 5e-62 62
Glaag_4444 YP_004436624.1 two component heavy metal response transcriptional regulator, winged helix family BAC0308 Protein 8e-55 61
Glaag_4444 YP_004436624.1 two component heavy metal response transcriptional regulator, winged helix family BAC0125 Protein 6e-53 60
Glaag_4444 YP_004436624.1 two component heavy metal response transcriptional regulator, winged helix family BAC0347 Protein 1e-55 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Glaag_4444 YP_004436624.1 two component heavy metal response transcriptional regulator, winged helix family VFG0596 Protein 5e-50 54
Glaag_4444 YP_004436624.1 two component heavy metal response transcriptional regulator, winged helix family VFG1389 Protein 1e-28 43