Gene Information

Name : Glaag_4409 (Glaag_4409)
Accession : YP_004436593.1
Strain :
Genome accession: NC_015498
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 137230 - 138903 bp
Length : 1674 bp
Strand : -
Note : KEGG: shn:Shewana3_4311 putative mercuric reductase; TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Heavy metal transport/detoxification protein; pyridine nucleotide-disulphide oxidoreductase dimerisation r

DNA sequence : 
ATGATCTTACTATCGATAGAAGGGATGACCTGTCCAAGTTGCGTCGCCCACGTTAAAGAAGCACTCGATGCGATCGAAGG
CGTGATTAAGGTTGAAATATCTTATGAAAACGCCAGCGCAGTGATCACCGCAAAGGGTGGGGTCAGCGTAACCGATCTCA
TCGGCGCAATTGAATCTCTCGGTTATATCGCAAAAGAATCCGCTGACACTGCAAAAGAAATTACTTCACCGAATGACTGC
TTTGACAACGAAAATGCAAGCAACACTGAAAGCAACCAAACTCAACATGTGGCGATTATCGGTACGGGTTCCGGCGCTTT
TGCCTGTGCTATCAAAGCCGCTGAAGGTGGTGCCAAGGTCACTCTTATTGAGGGAGCCGATGTGATTGGCGGCTGTTGCG
TTAATGTCGGCTGCGTACCCTCAAAAATTCTGATCCGCGCCGCTCAATTGGCTCAGCAGCAACGCAATAATCCCTTTGCC
GGACTGGAAAATCATGCGCCCCAATTGAGTCGAGCCTTGTTGACTCAGCAGCAGACCGCTCGGGTCGAAGAGCTGCGCGC
GGCAAAGTACCAGAATATTCTGGAGACAAATCCTGCGCTTAGTTTACTTAAAGGTTGGGCGCAATTTAAAAATGCCAGCA
CCCTGATAGTCAGAAAAAATGATGGAACCGAGCAGGAAGTTCACGCCGATAAAATCCTGATCGCTACGGGCTCCACGCCA
ACCATTCCTCCTATTGATGGTTTAACTGAAACTCCTTATTGGACGTCTACCGAATCTCTGTTTGCTCAGGAATTGCCGCA
GCACCTGGTGGTGATTGGCTCATCGGTCGTTGCGCTGGAAATTGCCCAGGCATATCGCCGTTTAGGCAGTGAAGTCACGG
TATTAGCAAGACATACATTGCTTTATTGGGAGGATCCCTTGCTGGGTGAAAAACTCACCGGCTGTTTTGAAAAAGAAGGC
ATTCGAGTATTAAACAATACGCAGGCTATCAAGGTGACCCACGATGGAAGCCAATTTACATTGGAAACTAACGCGGGCGA
TCTACGCTGCGATCGTTTGCTGGTAAGCACCGGGCGACACGCCAATAGCGACCAACTCAATCTCGACGCGGTGGGTGTCA
CGACCAACAAAAAGAGAGAAATCGTTGTTAACGAAAGCATGGAAACGAATGTGCCCGGTATTTTCGCCGCCGGAGACTGC
TGCAACATGCCACAATTCGTCTATGTCGCCGCGGCCGCCGGAAGCCGTGCCGGTATTAATATGACGGGCGGAGACGCCAA
ACTTGACTTGTCCACCATGCCGGCAGTGATCTTTACCGATCCTCAAGTGGCCACTGTTGGACTCACGGAAGAACAAGCGA
AAGCTCAAGGCATTGCAACTGACAGCCGCGTGTTGGAGATGGAAAATGTACCGCGCGCCTTGGCCAATTTCGAAACCGAT
GGTTTTATCAAACTGGTGGTTGAAAAGGCTAGTGGGCGCCTGATCGGTGCGCAGATCCTGGCCCACGAAGGCGGCGAACT
GATCCAGAGTGCAGCTTTAGCCATCGGGAACCGTATGACGGTGATCGAATTAGCCGACCAACTTTTCCCTTACTTGACCA
TGGTGGAAGGCTTAAAACTCTGCGCGCAAACCTTTAACAAGGATGTTAAAGAGTTGTCTTGCTGCGCCGGATAA

Protein sequence : 
MILLSIEGMTCPSCVAHVKEALDAIEGVIKVEISYENASAVITAKGGVSVTDLIGAIESLGYIAKESADTAKEITSPNDC
FDNENASNTESNQTQHVAIIGTGSGAFACAIKAAEGGAKVTLIEGADVIGGCCVNVGCVPSKILIRAAQLAQQQRNNPFA
GLENHAPQLSRALLTQQQTARVEELRAAKYQNILETNPALSLLKGWAQFKNASTLIVRKNDGTEQEVHADKILIATGSTP
TIPPIDGLTETPYWTSTESLFAQELPQHLVVIGSSVVALEIAQAYRRLGSEVTVLARHTLLYWEDPLLGEKLTGCFEKEG
IRVLNNTQAIKVTHDGSQFTLETNAGDLRCDRLLVSTGRHANSDQLNLDAVGVTTNKKREIVVNESMETNVPGIFAAGDC
CNMPQFVYVAAAAGSRAGINMTGGDAKLDLSTMPAVIFTDPQVATVGLTEEQAKAQGIATDSRVLEMENVPRALANFETD
GFIKLVVEKASGRLIGAQILAHEGGELIQSAALAIGNRMTVIELADQLFPYLTMVEGLKLCAQTFNKDVKELSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 7e-135 58
merA AGK07079.1 MerA Not tested SGI1 Protein 4e-135 57
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 7e-133 57
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 5e-133 57
merA AFG30120.1 MerA Not tested PAGI-2 Protein 5e-133 57
merA ABQ57371.1 MerA Not tested SGI1 Protein 4e-135 57
merA AGK07021.1 MerA Not tested SGI1 Protein 4e-135 57
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 6e-130 56
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 7e-130 56
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 1e-126 55

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Glaag_4409 YP_004436593.1 mercuric reductase BAC0652 Protein 2e-130 56
Glaag_4409 YP_004436593.1 mercuric reductase BAC0653 Protein 1e-132 56
Glaag_4409 YP_004436593.1 mercuric reductase BAC0650 Protein 2e-127 55