Gene Information

Name : PNA2_1581 (PNA2_1581)
Accession : YP_004424500.1
Strain : Pyrococcus sp. NA2
Genome accession: NC_015474
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 1466792 - 1467955 bp
Length : 1164 bp
Strand : +
Note : -

DNA sequence :
ATGAGGTTCTCAACTAAAGCTATTCATGTTGGTGAAAATCCAAGAGAGATGCAGTACGGAGACGTTGTTTCCCCGATTCA
CCTCTCGACCACTTTTGCAAAGAAGAGCGTGAGGGAAGTTGAGAAGGGTTACGTTTACTCAAGGACTGGCAACCCCACAA
GGGACAGCCTTGAGAAAAAGCTGGCGGCACTTGAAAACGCCAAGTATGGGTTAGCATTTTCCTCGGGGTTAGCGGCTGAG
TCAACGATACTCTTGGCTTTACTAAAGAAAGGAGATCATGTCGTAGCTTTCGATGACCTTTACGGTGGCACTAAGAGGCT
GTTCAACCAAGTTATGGAGCGCTTTGGGATTGAGTTCACCTATGTGGACGCAAGAGATCCTGAGAACGTTAGAAAGGCGA
TAAAAGAGAATACAAAGATGATCTGGCTCGAAACTCCCACAAATCCCCTCTTAAAGCTGGCTGATATTAAGGCAATATCC
GAGATTGCACATGAGAGAGACATAATCGTTGTGGTGGACAATACATTTGCGAGTCCATACTTCCAGAATCCCCTTGACTT
AGGTGCAGATATAGTTCTCCATAGTGTCACCAAGTATCTCAGTGGGCACTCCGACGTTGTGGGTGGGGCGGTTATGCTAA
ACGACGATGAGCTTTATGAAAAGCTGAAGTTCCACCAGAACGCAGTGGGTGCAATTTTGTCACCCTTTGACTCTTGGCTC
GTTATGAGGGGGATTAAGACACTCGCCGTCAGGATGGAGAAGCATGAGAAAAACGCCATGAGGATTGCAGAGTATCTAGA
AGAGCATCTGCTGGTTGAGAAAGTTTACTATCCTGGTTTGCCGTCACATCCACAATATGAACTCGCAAAGAGACAGATGC
GTGGTTTTAGTGGAATGCTTTCATTCGAACTCAAAGGAGGACTGAAAGAGGCCGTGAAGTTCGTGGAGAACCTTGAAATC
TTTGCGTTGGCTGAAAGCCTCGGCGGGGTGGAATCCCTAATTGAGCTCCCAGCTTTAATGACCCATGCTTCTCTTCCGAA
GGAAGAAAGGGAGAGAATCGGCATAAAGGACTCCCTCATCAGAGTTTCAGTTGGAATAGAAGACGTTGAAGACCTGATTG
AAGACTTGGAGAGGGGCTTTGAGGCGGTGAGAAGATGCTATTGA

Protein sequence :
MRFSTKAIHVGENPREMQYGDVVSPIHLSTTFAKKSVREVEKGYVYSRTGNPTRDSLEKKLAALENAKYGLAFSSGLAAE
STILLALLKKGDHVVAFDDLYGGTKRLFNQVMERFGIEFTYVDARDPENVRKAIKENTKMIWLETPTNPLLKLADIKAIS
EIAHERDIIVVVDNTFASPYFQNPLDLGADIVLHSVTKYLSGHSDVVGGAVMLNDDELYEKLKFHQNAVGAILSPFDSWL
VMRGIKTLAVRMEKHEKNAMRIAEYLEEHLLVEKVYYPGLPSHPQYELAKRQMRGFSGMLSFELKGGLKEAVKFVENLEI
FALAESLGGVESLIELPALMTHASLPKEERERIGIKDSLIRVSVGIEDVEDLIEDLERGFEAVRRCY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-79 49
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-80 49
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-65 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PNA2_1581 YP_004424500.1 cystathionine gamma-lyase BAC0207 Protein 4e-68 42