Gene Information

Name : Spico_0394 (Spico_0394)
Accession : YP_004411005.1
Strain : Sphaerochaeta coccoides DSM 17374
Genome accession: NC_015436
Putative virulence/resistance : Resistance
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 463456 - 464130 bp
Length : 675 bp
Strand : -
Note : COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: amt:Amet_1518 two component transcriptional regulator; PFAM: Signal transduction response regulator, rec

DNA sequence : 
ATGAATAAGATTCTGGTCGTTGACGATGACCCTCATCTTCGCGAATTGGTAAGGATTATCTTGCAAAAGGAAGGGTTTGC
CGTATACGAGGCCGCCGATGGGCTTGAAGCTCTTTCAAAGCTGGAAACATCAAAAGCCGACCTTGCCATCATTGACCTGA
TGATGCCGAACATGGATGGCTTTGAGCTGTGTCAGGAACTTCGAGCATCTTATGATATTCCCGTGCTCATGTTGACGGCA
AAAGGAGAAACCGCGCAGAAAATCAAAGGTTTTCAGGCGGGAGCGGATGATTACCTGGTCAAACCCTTTGAGCCGTTGGA
ATTGATGGCACGGGTGAAAGCACTGTTGAAACGCTATCAGATCATTGCCTCGCAGAATGTCCAAATTGGCAAGCTGATGA
TGAACCGGAAGAATTATGAAGTGATTGCGGGCAATATGAAGTTCACCCTTCCCCTCAAGGAATTTGAACTTCTGTTCAAG
CTGGCAGGATATCCCGGACGGACATTCTCACGTGATACGTTGATTGAAGATATCTGGGGTTATGGTTTCGAGGGCAATGA
ACGGACGCTTGATGTCCATATCAACCGTCTGCGCCAACGTTTCCCGGAAGAAAAAACCGATTTCAGGATTACGACCATCC
GTGGACTGGGTTATCGTCTGGAAGTAGATTCATGA

Protein sequence : 
MNKILVVDDDPHLRELVRIILQKEGFAVYEAADGLEALSKLETSKADLAIIDLMMPNMDGFELCQELRASYDIPVLMLTA
KGETAQKIKGFQAGADDYLVKPFEPLELMARVKALLKRYQIIASQNVQIGKLMMNRKNYEVIAGNMKFTLPLKEFELLFK
LAGYPGRTFSRDTLIEDIWGYGFEGNERTLDVHINRLRQRFPEEKTDFRITTIRGLGYRLEVDS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanRB YP_008394254.1 DNA-binding response regulator VanRB Not tested Not named Protein 6e-33 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spico_0394 YP_004411005.1 winged helix family two component transcriptional regulator HE999704.1.gene2815. Protein 3e-33 42
Spico_0394 YP_004411005.1 winged helix family two component transcriptional regulator AF310956.2.orf0.gene Protein 2e-33 41
Spico_0394 YP_004411005.1 winged helix family two component transcriptional regulator AF162694.1.orf4.gene Protein 9e-29 41
Spico_0394 YP_004411005.1 winged helix family two component transcriptional regulator AE016830.1.gene1681. Protein 9e-33 41