Gene Information

Name : Spico_0349 (Spico_0349)
Accession : YP_004410961.1
Strain : Sphaerochaeta coccoides DSM 17374
Genome accession: NC_015436
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 401221 - 402639 bp
Length : 1419 bp
Strand : +
Note : COGs: COG0469 Pyruvate kinase; InterPro IPR015793:IPR015795:IPR001697; KEGG: cob:COB47_1291 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; IMG refe

DNA sequence : 
ATGAGAAAGACCAAGATCATTTGCACCATGGGACCTGCCTTGGATGATGAAACCAAGCTGCGCAAGGTCATGCAACAAGA
CATGGATTGCGCCAGGTTCAACTTTTCACATGGGAACCATGCGGAGCAGAAAACACGCATGGATCGGGTGCGCAGGATAC
GGGAAGAACTTGACCTGCCCATAGCGCTTCTCCTGGATACAAAAGGACCGGAGATGCGGGTTCGCAAGTTCGCTGAATCA
CAGATTACCCTTGAGGCCGGGATGACCTTCACCCTGTATGCCGATGATTCCATCATGGGCGATACCTCCGGCGTTTCCAT
TACATACCCGTATCTCGCTGAAGAAGTCAGCATTGGAACGCGGATTCTGCTTGATGATGGCTTGATTGAATTGGGCGTGA
GCAAGATAGAGGGCAAGGATGTGATTTGTACAGTCATCTCCGGTGGGCCTCTGTCCAATAATAAGGGGATTAACATTCCC
GGTATTAACCTTGACGTTCCTTATATCAATGAGACCGACAGGGCGGACATTCTTTTTGGCATAGAGCAGGATATAGATTT
CATAGCTGCTTCTTTTGTCCGTACTGCGGACGATGTACGCAAGTTGCGCCGGTTGCTTGATGCCAACGGAGGCAAAAGGA
TAAAGATTATCAGCAAGATTGAGAACCGTTCCGGCTTGGACAATCTTGACGAGATACTTGCCATCAGCGATGGCATCATG
ATTGCCCGTGGCGACATGGGTGTCGAGATTCCCTTCCCAGAGCTGCCCCCTGTCCAGAAGGACATAATCAAGAAATGCTA
CAGGGCGGGAAAATTCAGTGTCACGGCTACGCAGATGCTTGAATCAATGACGCACAATCCCCGTCCGACACGAGCCGAAG
TCTCTGATGTGGCCAATGCTATCTACGATGGAACTACCGCCATCATGCTGAGTGGTGAAACTGCCGCCGGAAAGTATCCT
GTGGAGGCTGCCCGTACCATGGCGACCATTGCCGAATATACCGAACAACAGATTGACTACAAGAAAAGATTTGCGACCAA
TCATCTGACTTTATCCCAGGATATTCCCAATGCCATCGGGAGCGCGGCGTGTGAATCCGCGTATTTCCTGGATGCCAAGG
CAATCGTCAGCATGACGATGACCGGACGTTCCGCTCATATGATTTCGCGCTACCGTCCCGCTTGTCCCATAATCGCGGCG
GTTTCCGATCCCGTTGCCGCCCGGACCCTGAACTTGGCTTTCGGCGTCAGGCCAGTCTTGGCGGAAGTTCAGCCGACGGT
ATCCGCCACGCTTGAGCATGGCGTCGAGCTGGCATTCAAGACTGGACTGGTGAAAAAAGGTGATCTCATTATCCTGACAA
GCGGGAACGTCATAGACACTCAGACAGCCGCCGATACCATGCATATCCGCGAGGCATAA

Protein sequence : 
MRKTKIICTMGPALDDETKLRKVMQQDMDCARFNFSHGNHAEQKTRMDRVRRIREELDLPIALLLDTKGPEMRVRKFAES
QITLEAGMTFTLYADDSIMGDTSGVSITYPYLAEEVSIGTRILLDDGLIELGVSKIEGKDVICTVISGGPLSNNKGINIP
GINLDVPYINETDRADILFGIEQDIDFIAASFVRTADDVRKLRRLLDANGGKRIKIISKIENRSGLDNLDEILAISDGIM
IARGDMGVEIPFPELPPVQKDIIKKCYRAGKFSVTATQMLESMTHNPRPTRAEVSDVANAIYDGTTAIMLSGETAAGKYP
VEAARTMATIAEYTEQQIDYKKRFATNHLTLSQDIPNAIGSAACESAYFLDAKAIVSMTMTGRSAHMISRYRPACPIIAA
VSDPVAARTLNLAFGVRPVLAEVQPTVSATLEHGVELAFKTGLVKKGDLIILTSGNVIDTQTAADTMHIREA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-92 45
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-92 45
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-92 45
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-92 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spico_0349 YP_004410961.1 pyruvate kinase VFG0479 Protein 4e-93 45