Gene Information

Name : Spico_1380 (Spico_1380)
Accession : YP_004411966.1
Strain : Sphaerochaeta coccoides DSM 17374
Genome accession: NC_015436
Putative virulence/resistance : Unknown
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 1616981 - 1618150 bp
Length : 1170 bp
Strand : +
Note : COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: cth:Cthe_2799 cystathionine gamma-synthase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cystathionine gamma-lyase; SPTR: Cystathionin

DNA sequence :
ATGAGTGAGGATTACAACTGTTCCCAGGAAACCATCATTGTCCACGGTGTCACTCCCTACGATTCCCGTACCGGAGCGAT
AAGCACTCCCATTTACCTGAGTTCAACCTTCCGCCATCCTGAACTTTTTCAATCGACAGGCTTTGACTATTCCCGCTCCC
TGAACCCCACGAGACTAGAGCTGGAAAACACCATTGCCCGTCTTGAGAAAGGACGTTACGGACTTGCGTTCGCTTCCGGC
ATGAGCGCAATATCCGCGCTCATCAAGCTGTTCGCGCCGGGCGACCATATCATTGTCTCGATAGATCTGTACGGTGGTAC
ATATCGCCTTTTCCATGATATCTACGAACCATACGGACTGCACTTCTCCTGGGTGGACACCGACGACCTTGAAGCAACAA
AGAATGCCCTGCGACCCGGAACGAAAGCTGTCTTCATTGAGACTCCCTCAAACCCCATGATGAAAGTCACTGACATCCGC
GCGACGGCGGATATCATCCATTCCCACGGACAGAAGCACGGGCAGGAAGGATACCTCATTGTGGACAATACTTTTCTTTC
CCCTTATTATCAAAATCCCCTGGAACTGGGGGCGGACTTTGTTGTCCATAGCGGGACAAAGTACATTTCCGGACACAATG
ACACGCTTTCAGGTTTCATTGTTCATGATGACGAGACAATCGCGGAAAAACTCCGTTTTCTCCAGATGAGCGAGGGTGGC
ACGCTCAGCCCCTTTGAGTCATGGCTGATTCTCCGGGGACTCAAAACTTTGGCCGTCCGCATGGACAGACAGAGCGAGAA
CGCCTTGGTCGTAGCCATGTGGTTGCAAACTCATCCCAAAGTCGAATCAGTCTACTATGTCGGCCTGCCCGACCATCCCC
ATCATGAGCTTTCCCTCCGCCAAAGCAAAGGCTTCGGGGGAATGGTTTCCTTCTCCCTCAAAGACTCCGCCGATGTGGCA
TCTCTTTTGAAGAACATACGGCTGATCCTGTTCGCCGAAAGTCTGGGAGGCGTGGAAACCCTCCTCACCTATCCCATGGT
TCAGACTCACCAAGCCATTCCCCCCGACATGAGGGAGCGGACAGGGGTCACCGACCGCCTGATGCGGTTGTCCGTCGGAC
TGGAACGAGCGCAGGACATAATAGCCGACCTTAAACAGGCTCTGGACTGA

Protein sequence :
MSEDYNCSQETIIVHGVTPYDSRTGAISTPIYLSSTFRHPELFQSTGFDYSRSLNPTRLELENTIARLEKGRYGLAFASG
MSAISALIKLFAPGDHIIVSIDLYGGTYRLFHDIYEPYGLHFSWVDTDDLEATKNALRPGTKAVFIETPSNPMMKVTDIR
ATADIIHSHGQKHGQEGYLIVDNTFLSPYYQNPLELGADFVVHSGTKYISGHNDTLSGFIVHDDETIAEKLRFLQMSEGG
TLSPFESWLILRGLKTLAVRMDRQSENALVVAMWLQTHPKVESVYYVGLPDHPHHELSLRQSKGFGGMVSFSLKDSADVA
SLLKNIRLILFAESLGGVETLLTYPMVQTHQAIPPDMRERTGVTDRLMRLSVGLERAQDIIADLKQALD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-82 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-83 43
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-69 41