Gene Information

Name : Mcup_0917 (Mcup_0917)
Accession : YP_004409506.1
Strain : Metallosphaera cuprina Ar-4
Genome accession: NC_015435
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : -
Position : 824192 - 825856 bp
Length : 1665 bp
Strand : -
Note : -

DNA sequence :
ATGAGGATAAGTAAGGAGAGATATTTCGAACTTTATGGTCCTACGGTGGGAGACAAGATAAGATTGGGAGACACGAACCT
TTACGTTACAGTTGAAAGGGATCTCATTTCACATGGGGACGAACTGGTTTTCGGAGCTGGAAAGACTGCTAGGGACGGTT
TGGGAATGTTACCCAACGCTAAGGGAGAAGGAGTTATGGATTTAATTATAACCAATGTAGTGATCCTGGACCCGGTGTTG
GGTGTCATTAAGGCTGACATAGGAGTTAAGGATGGGTTGATTGTTGGGATAGGCCACGGTGGGAACCCCTTTACGATGGA
TAACGTGGATTTCGTTTTAGGCTCTAGAACTGAGATAATTTCTGGAGAGGGATTGATAGCCACTCCTGGCTTTATAGATT
CCCATGTTCATTGGATAGCTTTGCAACAAATTTATGACGCGTTGTCCGCAGGATTCACTACCATAATAGGGGGTGGAACT
GGGCCGGCAGAGGGGACTAAGGCTACCACTGTCACTCCTGGCAAATCTTTAAGGGTGATAATGGCGGCGTTAGATAACTT
CCCTATAAATTTCGCCTTAACTGCTAAGGGTTCCTCCTCAAGAACATCAATGGAAGAGGACGTTAAGGAAGGCGCTTCGG
GCTTTAAAATCCATGAAGATTGGGGAGCTATGCCAAGGGTGATAGATGAGACCTTAAACGTTGCAGACGAGTATGACGTG
CAAGTTACAATACATACCGACACTTCCAACGAGAGTGGATATCTAGAAGACACTTTGAACGCAATAGGGGGAAGGACCAT
TCACGCATATCACGTAGAAGGTGCAGGAGGGGGTCACGCTCCAGACATAATAAAAATTTCCGGCGAACCCTACGTGTTAC
CGTCTTCAACGAACCCAACAAAGCCATTTACTATACACACTTACGATGAGCACTTAGAGATGTTAATGGCTGTACATCAC
TTGAATCCTAAGGTTCCAGAGGACATAGCTTACGCTGAGTCGAGAATAAGGGAAGAGACAATGGCTGCGGAAGATTATTT
ACACGATGTGGGAGCGATAAGCATGATGTCCTCAGACTCTCAAGCTATGGGTAGAGTAGGTGAAACTGGAATAAGGACTT
TCCAGTTAGCTCATAAGATGAAGGAGATGATAGAGATGGATGACAATTCTAGGGTTCTGAGATATTTGGCTAAGATAACC
GTAAATCCGGCAATAACCCACGGGATATTTGACTACGTTGGCTCATTACAGCCCGGTAAAATTGCTGATATAGTGTTATG
GGATCCTAGATTCTTCCCAGCTAAACCTTATATGGTGATTAAAGGTGGAATGATAGCCTGGGCCATGATGGGGGATACCA
ATGCCTCAATAGCGTACGCGCAACCCTTATCTTATAAGCCGATGTTCGGATACTACGCTCCACAATTTACCTCATACGCG
TTCTCATCTCAAGAGGGTGTAAAAGAGGTTGAGAAGGTTGTTAAGAGGAGAGTATTACCAATAAAGAACACTAGAAAGTT
AGGGAAAAAGGATATGATTAGAAATAACACGTTGCCCAAAATTGAGGTAGATCCAGATACCTATGAGGTCAAAATCGATG
GAAAGGTTCCGAAGGTGAAACCATCGGAGACTCTGCCCTTAACCAGGTTATATTTCATGTTTTAG

Protein sequence :
MRISKERYFELYGPTVGDKIRLGDTNLYVTVERDLISHGDELVFGAGKTARDGLGMLPNAKGEGVMDLIITNVVILDPVL
GVIKADIGVKDGLIVGIGHGGNPFTMDNVDFVLGSRTEIISGEGLIATPGFIDSHVHWIALQQIYDALSAGFTTIIGGGT
GPAEGTKATTVTPGKSLRVIMAALDNFPINFALTAKGSSSRTSMEEDVKEGASGFKIHEDWGAMPRVIDETLNVADEYDV
QVTIHTDTSNESGYLEDTLNAIGGRTIHAYHVEGAGGGHAPDIIKISGEPYVLPSSTNPTKPFTIHTYDEHLEMLMAVHH
LNPKVPEDIAYAESRIREETMAAEDYLHDVGAISMMSSDSQAMGRVGETGIRTFQLAHKMKEMIEMDDNSRVLRYLAKIT
VNPAITHGIFDYVGSLQPGKIADIVLWDPRFFPAKPYMVIKGGMIAWAMMGDTNASIAYAQPLSYKPMFGYYAPQFTSYA
FSSQEGVKEVEKVVKRRVLPIKNTRKLGKKDMIRNNTLPKIEVDPDTYEVKIDGKVPKVKPSETLPLTRLYFMF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 8e-123 53
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 8e-123 53
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-111 50
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-111 50
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-111 50
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-111 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mcup_0917 YP_004409506.1 urease subunit alpha VFG0270 Protein 1e-114 52