Gene Information

Name : VAB18032_07120 (VAB18032_07120)
Accession : YP_004403148.1
Strain : Verrucosispora maris AB-18-032
Genome accession: NC_015434
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase and ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 551478 - 553154 bp
Length : 1677 bp
Strand : -
Note : COG1021 Peptide arylation enzymes

DNA sequence : 
ATGGCCGGCTCCGCCGGTGATCGGCGTACGGGAGGCCCCGTGGCTGTTCGTGAAGGCTTCACCCCCTGGCCGGCGGAGTT
CGCCGCCCGATACCGCGAGGCCGGTTACTGGCGCGGTGAGGTGCTCGGTGACCTGCTGCGCCCCTGGGCCGACTGGGCCG
ACGAGGCTCGTGACCCGGGGCGTACCGCCGTGGTCACCCGCCACGGCCGGCACACCTACGGCGAACTCGACGCCCGTGCC
GACGAGTTGGCCGCGGGCCTGTTCGAGCTGGGCGTACGCCCCGGCGACGGGGTGGTCGTGCAGCTGCCCAACACCGTCGA
GTTCCTGGTCACCTGCGTGGCGCTGTTCCGCCTGGGCGCGCTGCCGGTGCTGGCCCTGCCGGCCCACCGTCGGGCCGAGC
TGACCTACCTGACCCAGTACGTCGGGGCCGTCGCCCTGGTGACCAGCGACCGGACACCCGGCGTGGACCACCGCACGGTG
GCGCAGGAGGTACGCGACGCCTGCCCCACGCTGCAACACGTACTTGTGGTCGGCGATCCCGGGCCGTTCCTGGCCTGGTC
GCAGGTGCGCGCCCCGGCCCGGGAACTGCCCCGCCCCGACCCGCAGGACGTGGCGTTCTTCCTGCTCTCCGGTGGGACGA
CCGGGTTGCCGAAGCTGATCCCCCGGACCCACGACGACTACGCCTTCCAGCTGCGCGCCACCGCCGAGGCGATGTCGTTC
GACCACCGGCACGCCTACCTCGCCGCGGTACCTGTCGCACACAACGCCGCCCTCGGCTGCCCCGGCGTGCTCGGCGCGCT
GCGCGTCGGCGGCCGGGCGGTGCTGGCCGCCAGCCCCAGCCCGGACGAGGTCTTCCCGCTGATCACCCAGGAGCGGGTCA
CCCTCACCACGGTCATGCCGGCCGTGCTGTCGCTGTGGGTCGAGACCGCCGACATGTTCGAGGTGAACCTGTCCGATCTG
GTCATCGAGGTCGGCGGGGCGGTGCTGCAACCCGACCTGGCCCGCGCGGTCCGTCCGGCCCTGGGTGCCACGCTCACCCA
CTGGTTCGGCATGGCCGAGGGGATGCTCTGCTTCACCCGTCCTGGCGACGGTGACGAGGCCGCGGCCACCACCCAGGGCA
CGCCGATGTGTGCCGACGACGAACTGCTCATCGTCGACGAGGCCGGCGAGCCCGTCGCGCCCGGCGAGGTCGGCGAGTTG
CTGGCGCGCGGGCCGTGCGTGCTGCGCGGCTACTACGCCGTACCCGAGCACAACCGGACGGTCTTCACCCCCGACGGTTT
CCTGCGCACCGGCGACCTGGCCCGGTTCGACGCCGAGGGCCGCCTGGTCATCTCCGGGCGGATCAAGGACGTCATCAACC
GGGGTGGCGAGAAGGTGATGGCCGACGAGGTCGAGGGGCACCTGCTGGCCCACGAGCGGGTCCGGGCGGCGGCGGTCGTC
CCGTTCCCCGACCGGCGGCTCGGCGAGAAGACCTGCGCGGTCATCGTCGCCGACGACCCGGCGCCCAGCCTGGTGGAGCT
ACGCAAGCTGCTGCGCGACCGGGGCCTGGCCGACTACAAGCTGCCGGACCGGTTGGAGGTCGTCGAGGCGTTGCCGCTGA
CGAACGTCGGCAAGGTCGACAAGCGGGCCCTGGCCGCGGCCGTCCTCGGCGACCTGACCACCGCCGCCAGCCGGTAG

Protein sequence : 
MAGSAGDRRTGGPVAVREGFTPWPAEFAARYREAGYWRGEVLGDLLRPWADWADEARDPGRTAVVTRHGRHTYGELDARA
DELAAGLFELGVRPGDGVVVQLPNTVEFLVTCVALFRLGALPVLALPAHRRAELTYLTQYVGAVALVTSDRTPGVDHRTV
AQEVRDACPTLQHVLVVGDPGPFLAWSQVRAPARELPRPDPQDVAFFLLSGGTTGLPKLIPRTHDDYAFQLRATAEAMSF
DHRHAYLAAVPVAHNAALGCPGVLGALRVGGRAVLAASPSPDEVFPLITQERVTLTTVMPAVLSLWVETADMFEVNLSDL
VIEVGGAVLQPDLARAVRPALGATLTHWFGMAEGMLCFTRPGDGDEAAATTQGTPMCADDELLIVDEAGEPVAPGEVGEL
LARGPCVLRGYYAVPEHNRTVFTPDGFLRTGDLARFDAEGRLVISGRIKDVINRGGEKVMADEVEGHLLAHERVRAAAVV
PFPDRRLGEKTCAVIVADDPAPSLVELRKLLRDRGLADYKLPDRLEVVEALPLTNVGKVDKRALAAAVLGDLTTAASR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-97 46
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-97 46
ybtE CAA21394.1 - Virulence HPI Protein 6e-97 46
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 5e-97 46
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 4e-96 46
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 5e-97 46
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-96 46
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-97 46
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 6e-97 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
VAB18032_07120 YP_004403148.1 AMP-dependent synthetase and ligase VFG1817 Protein 5e-106 47
VAB18032_07120 YP_004403148.1 AMP-dependent synthetase and ligase VFG0168 Protein 1e-102 45
VAB18032_07120 YP_004403148.1 AMP-dependent synthetase and ligase VFG0932 Protein 2e-94 42