Gene Information

Name : VAB18032_24835 (VAB18032_24835)
Accession : YP_004406665.1
Strain : Verrucosispora maris AB-18-032
Genome accession: NC_015434
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 4515787 - 4517424 bp
Length : 1638 bp
Strand : +
Note : COG1021 Peptide arylation enzymes

DNA sequence : 
GTGAACCCGTCCGGGGTGGTGCCGTGGCCGACGGAGGTGGCGCAGGTGTACCGGGCGGCGGGCTGCTGGCGCGGCCGGCC
GCTCGGGTCCTACCTGTGGGAGTGGGCAGAGCGGCACGGTGACCGGATCGCGGTGGTCGACGGCGACCGCCGACTGAGCT
ATCACGAACTCGCGGTCCGCACCGACCAGCTCGCCGAGCGCCTGGCCGGTCTCGGACTCGGTCGGGGTGACGCGGTGCTC
GTCCAACTGCCCAACTGTGCCGAGTTCGTGCTCACCACGCTCGCCTGTTTCCGACTCGGCGTGGTGCCGGTGATGATGTT
GCCGCCGCACCGCGAGTACGAGTTGACCGCCATCGGGGCGCACGTCGAGGCCCGGGCGTTGATCGTGCCCGCGCGGTGGC
GCGACTACGACCACGAGGCCCTGGCCCACCGGGTGGTGGCCGCCTGGCCGCATCCGGCGCATGTGCTGGTGGCCGGCGGG
GACACCGTACCGGGGCGGATCGACCTGTGTGGACCCGCCACGCCCCCCGGTGACGTCGCGGCCCGCCGGGACCGGCTGGA
CCGGGCCGCCCCCGACTCGGCCGAGGTGGCGCTGTTCCTGTTGTCCGGTGGGACGACGGGCGTGCCGAAGGTGATCAGCC
GGACCCACGACGACTACGAGTACAACATTCGGCAGGTCGTCGCGGCCTGCGAGTTCGGCCCCGACACGGTCTACCTGACC
GTGCTTCCGGCCGGGCACAACTTCCCGCTGGCCAACCCGGGCATTCTCGGCACCCTGAGCGTCGGTGGTCGGGTGGTGCT
GCTGCCCTCGCCACGCCCGGAGGCGGTCTTCGCCGCGATCGAGCGGGAACGGGTCACGGTCACCTCGGCGGTGCCGGCGG
TCGCCCTGCGCTGGATGGAGGCCGCCGCGGACTGCGGGTACGACCTGTCGAGCCTGCGTCACGTGCAGGTCGGCGGCTCC
CCGCTGGCGCCCGAGGTGGCGGCGCGGATCGGCCCCGCGCTGGGCTGCCGACTCCAGCAGGTGTACGGCATGGCCGAGGG
GCTGATCTGTTACACCCGGCCGGACGCCCCCGACGAGGTGGCCCACCGGACGCAGGGCACCCCGATCAGCGAGTACGACG
AGTTGCTCATCGTCGACGCCGACGGGGTCGCCGTGCCCTCCGGGCAGATCGGCGAGCTGTGGACCCGGGGTCCGTACACG
CCGCGGGGCTACTACGGGGTCCCCGCACAGAACGCCGAGTCGTTCACGCCCGACGGCTGGTACCGCACCGGGGACCTGGT
GCGCCGTACGCCGGGTGGTGAGGTCGTGGTCTGCGGCCGGGTGAAGGACCTGATCAACCGGGGCGGTGAGAAGATCTCGG
CGGCCGAGGTGGAGACCCTCGTCCAGGAGCTGCCGGCGGTGGCCGAGGCGGCCGTGGTGCCGGTCGCGGACCCGGAGGTC
GGCGAGCGGGCCTTCCTGTTCGTCCGGCTCCTGCCGGGCCACGAGCTGGGTCTGGCCGACGTCGCCGAGGCGTTCGCGGC
GCGCGGGGTGGCCGCCTTCAAGGTGCCGGAGCGGCTGGCCGTCCTCGACGAGCTGCCGCACACCCCGGTTGGCAAGCCGG
ACAAGGCCGCGCTGCGCCGACTGGTCGCCACCGCCTGA

Protein sequence : 
MNPSGVVPWPTEVAQVYRAAGCWRGRPLGSYLWEWAERHGDRIAVVDGDRRLSYHELAVRTDQLAERLAGLGLGRGDAVL
VQLPNCAEFVLTTLACFRLGVVPVMMLPPHREYELTAIGAHVEARALIVPARWRDYDHEALAHRVVAAWPHPAHVLVAGG
DTVPGRIDLCGPATPPGDVAARRDRLDRAAPDSAEVALFLLSGGTTGVPKVISRTHDDYEYNIRQVVAACEFGPDTVYLT
VLPAGHNFPLANPGILGTLSVGGRVVLLPSPRPEAVFAAIERERVTVTSAVPAVALRWMEAAADCGYDLSSLRHVQVGGS
PLAPEVAARIGPALGCRLQQVYGMAEGLICYTRPDAPDEVAHRTQGTPISEYDELLIVDADGVAVPSGQIGELWTRGPYT
PRGYYGVPAQNAESFTPDGWYRTGDLVRRTPGGEVVVCGRVKDLINRGGEKISAAEVETLVQELPAVAEAAVVPVADPEV
GERAFLFVRLLPGHELGLADVAEAFAARGVAAFKVPERLAVLDELPHTPVGKPDKAALRRLVATA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 4e-73 44
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-73 44
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-73 43
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 4e-73 43
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-73 43
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-73 43
ybtE CAA21394.1 - Virulence HPI Protein 4e-73 43
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 3e-73 43
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 5e-73 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
VAB18032_24835 YP_004406665.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 1e-78 45
VAB18032_24835 YP_004406665.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-81 45
VAB18032_24835 YP_004406665.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 3e-76 41