Gene Information

Name : ureC (VAB18032_13420)
Accession : YP_004404396.1
Strain : Verrucosispora maris AB-18-032
Genome accession: NC_015434
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1920638 - 1922356 bp
Length : 1719 bp
Strand : +
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAGTCAGATTTCGCGGCAAGAGTATGCCGGGATGTACGGCCCCACCACGGGCGACCAGATCCGGTTGGCCGACACCGA
CCTCTACATCGAGATCGAGAAGGACCTGCGGGTCCTGGGCGACGAGGTCATGTACGGCGGCGGCAAGACCCTACGCGACG
GCATGGGCAGCAGCAGTCAGGCCACCAGCGCCGAAGGGGTGCTGGACCTGGTGATCACCAATGTCACCGTCCTCGACGCG
CTGCTCGGCGTGATCAAAGCCGATGTCGGCATCAAGGACGGCAGGATCGCCGGCATCGGCAAGGCCGGCAACCCGAACAT
CATGGACGGGGTCACTCCCGCTCTGGTGACCGGACCGGGAACCGACGCGATCTCCGGTGAACACCTGATCCTGACCGCGG
GCGGCATCGACGCCCACGTCCACCTGGTCACGCCGTTCCAGGTGCAGACGGCGCTCAGCAACGGGGTGACCACCCTCTGG
GGTGGCGGCACCGGCCCCACCGACAGCACAAACGGCGTCACCATCACGCCGGGCCCGTGGAACATCCACAACATGATGCG
TGCCTTCGAGACCCTGCCGATCAACATCGGCCTGCTGGGCAAGGGCAACAGCAGTGGGCGCGCGCCGCTGGTGGAGCAGA
TCATGGCCGGGGTGCCGAGCTTCAAGATCCACGAGGACTGGGGTGCGCCGCCTGCGGTGATCCGCTCGTGCCTGGCGGTC
GCCGACGAGTACGACGTGCAGGTCAGCATCCACACCGACACCCTCAACGAGAGCGGCTACATCGAGGACTCGATCGCCGC
CTTCGAGGGCCGGACCATCCACACCTTCCACACCGAGGGCGCCGGTGGCGGCCACGCGCCGGACATCATCAAGGTGGCCG
GTCAGATGAACGTGCTGCCCGGCTCGACCACGCCCACCGTGCCGTACGGCATCAACAGCCAGTCCGAGCTGTACGACATG
ATCATGGTCTGCCACAACTTCAACCCGAAGGTCCCCTCCGACGTGGCATTCGTGGAGAGCCGCATCCGCACCGAGACCAT
CGCGGCCGAGGACGTGCTGCTCGACGAGGGCGTCATCTCGATGATGCAGAGCGACTCGCAGGCCATGGGCCGGGTGGGGG
AGACCTGGCTGCGCACCATCCAGCTCGCCGGCCAGATGAAGAACGTCCGCGGCAAGCTCGCCGAGGACTCGTCAAGCAAC
GACAACTTCCGGGTGCTGCGCTACGTCGCCAAGATGACCATCAACCCGGCCATCACCCAGGGCGTCTCGCACGTCATCGG
ATCGGTGACCCCGGGCAAGCTGGCCGACCTGGTGCTCTGGGAACCCGCCTTCTTCGGCGTGAAGCCCAAGATGGTGCTCA
AGGGCGGCATGATCGCCTGGTCGATCATGGGCGACCCGAACGCCTCGCTGCCCACACCCCAGCCGGTCTACTACCGGCCC
TCGTTCGGCGCGACCGGCACCCAGGTCGCCAAGAACTGCGTCACCTTCGTCTCCAAGGCCGCCCACGAGAACGGCATCGG
CGAACAGTTGGGCCTGCAACGGCAGGTCATGCCGGTCTACCAGTGCCGCAACCTGACCAAGCGGGACATGGTGCGCAACG
ACCGGACCCCGAAGCTCGAGGTCGACCCCGAGACCTTCGCGGTGAAGATGGACGGCGTCCACGCGACCGTGCCGGCGGCC
AAGAACCTCCCGATGAGCCAGCTCTACTTCTTCAGCTGA

Protein sequence :
MSQISRQEYAGMYGPTTGDQIRLADTDLYIEIEKDLRVLGDEVMYGGGKTLRDGMGSSSQATSAEGVLDLVITNVTVLDA
LLGVIKADVGIKDGRIAGIGKAGNPNIMDGVTPALVTGPGTDAISGEHLILTAGGIDAHVHLVTPFQVQTALSNGVTTLW
GGGTGPTDSTNGVTITPGPWNIHNMMRAFETLPINIGLLGKGNSSGRAPLVEQIMAGVPSFKIHEDWGAPPAVIRSCLAV
ADEYDVQVSIHTDTLNESGYIEDSIAAFEGRTIHTFHTEGAGGGHAPDIIKVAGQMNVLPGSTTPTVPYGINSQSELYDM
IMVCHNFNPKVPSDVAFVESRIRTETIAAEDVLLDEGVISMMQSDSQAMGRVGETWLRTIQLAGQMKNVRGKLAEDSSSN
DNFRVLRYVAKMTINPAITQGVSHVIGSVTPGKLADLVLWEPAFFGVKPKMVLKGGMIAWSIMGDPNASLPTPQPVYYRP
SFGATGTQVAKNCVTFVSKAAHENGIGEQLGLQRQVMPVYQCRNLTKRDMVRNDRTPKLEVDPETFAVKMDGVHATVPAA
KNLPMSQLYFFS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-148 58
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-148 58
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-140 57
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-140 57
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-140 57
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-140 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_004404396.1 urease subunit alpha VFG0270 Protein 5e-152 58