Gene Information

Name : Lbuc_2431 (Lbuc_2431)
Accession : YP_004399673.1
Strain :
Genome accession: NC_015429
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.3
Position : 4184 - 6103 bp
Length : 1920 bp
Strand : +
Note : TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: sag:SAG1257 cation transporter E1-E2 family ATPase; PFAM: ATPase, P-type, ATPase-as

DNA sequence :
ATGTCTGATCAACAAGCAAAATTATCTGAAAAGGTAGAGCGTGAACCTTTCTGGAAGCAAAAAGAAAACATTAAGGTCTA
TATTTCAGCGTTATTACTTGTGATTAGTTGGTTTTTGGGCGAGCAATTAGGAGAAGAACATCTTCTTCCAATGATCGGCT
ACGCAGCATCCATTTTAATTGGTGGATATACACTGTTTATTAAAGGTCTTAAAAATCTAAGCAGATTAAAATTCGATATG
AATACGCTCATGACGATTGCTATTATAGGTGCTGCGATCATTGGTAAATGGGGTGAAGGCGCAACAGTTGTTATCCTATT
CGCTATCAGTGAAGCGTTAGAACGTTATTCAACGGATAAAGCTCGTCAATCTATTGGATCATTAATGGATATTGCCCCAA
AAGAAGCATTAATTCGGCGTGGAAATGAAGAAATGATGATTCACGTTGAAGATATTCAAGTTGGAGACATTATGATTGTA
AAACCTGGTCAAAAATTAGCAATGGATGGATTAGTTATTAAAGGTACATCTACACTAAATCAGGCTGCTATTACTGGGGA
AAGTGTTCCAGTAACAAAAACAATTGATGATGAAGTGTTTGCAGGAACATTGAATGAAGAAGGGTTACTTGAAGTTAAAG
TAACAAAACGAGATGAAGATACTACTATTTCAAAAATTATTCATCTTGTAGAAGAAGCTCAAGCAGAACGATCACCTTCT
CAAGCATTTGTCGATAAATTTGCGAAATACTATACACCAGCTATTGTGCTTTTAGCTCTTTTAATTGCAGTTGTTCCTCC
ATTATTCGGTGGAGATTGGAGCCAATGGCTTTATCAAGGTTTAGCTGTGTTAGTAGTTGGTTGTCCGTGTGCTTTAGTTG
TTTCAACTCCAGTTGCCGTAGTTACTGCAATAGGGAATGCGGCAAAAAATGGTGTGTTAATTAAAGGTGGTATCCATTTA
GAAGAAGCAGGACACTTAAAAGCCATTGCTTTTGATAAAACAGGAACATTAACAAAAGGTATTCCTGCTATAACAGACAT
CGTGACGTATGGTGGAAATGAAAATGAATTGCTTACAGTTACAGCAGCCATTGAAAAAGGATCACAACATCCACTTGCTT
CAGCCATTGTAAGAAAAGCAGAAGAAAATGGATTGAATTTAAATGGTGTTTCGGTTGAAGAGTTCCAATCTATTACAGGT
AAAGGTGTAAAAGCAAAAGTAAATAACGAAATGTATTATGTAGGAAGTCCAAATCTGTTTGAAGAATTACATCAAACAAT
TGAAAGTACCATCAAAGAAAGAATTACTCGTATGCAAACAGAAGGAAAAACCGTAATGGTTTTAGGAACGGAAAAAGAAA
TTCTTTCGTTAATTGCCGTAGCAGATGAAATGAGAGAAACATCAAAAGAAGTTATTAGTAAATTGAATCATATCGGAATT
GAAACAGTAATGCTGACTGGTGATAATCAAAGAACCGCAGAAGCAATTGGAAAACAAGTCGGTGTTTCGGATATTAAAGC
TGATTTATTACCAGAGGATAAGCTGAATTTCATTAAAGAACTTCTTGGAAAACATCAAAGTGTAGGAATGGTTGGAGATG
GTGTTAATGATGCACCAGCACTTGCAGCTTCTTCAGTTGGTGTCGCAATGGGTGGTGCTGGAACGGATACTGCATTAGAA
ACGGCTGATATTGCTTTAATGGCTGATGATTTAAGCAAATTGCCATATACTATCAAATTAAGCCGTAAGGCTTTAGCAAT
TATCAAACAAAACATTACCTTCTCTTTAGCCGTTAAATTAGTAGCATTACTATTAGTTATGCCTGGTTGGTTAACTTTAT
GGATAGCAATTTTTGCCGATATGGGAGCAACGTTACTTGTTACACTAAACAGTTTACGACTATTGAAGGTTAAAGGGTAG

Protein sequence :
MSDQQAKLSEKVEREPFWKQKENIKVYISALLLVISWFLGEQLGEEHLLPMIGYAASILIGGYTLFIKGLKNLSRLKFDM
NTLMTIAIIGAAIIGKWGEGATVVILFAISEALERYSTDKARQSIGSLMDIAPKEALIRRGNEEMMIHVEDIQVGDIMIV
KPGQKLAMDGLVIKGTSTLNQAAITGESVPVTKTIDDEVFAGTLNEEGLLEVKVTKRDEDTTISKIIHLVEEAQAERSPS
QAFVDKFAKYYTPAIVLLALLIAVVPPLFGGDWSQWLYQGLAVLVVGCPCALVVSTPVAVVTAIGNAAKNGVLIKGGIHL
EEAGHLKAIAFDKTGTLTKGIPAITDIVTYGGNENELLTVTAAIEKGSQHPLASAIVRKAEENGLNLNGVSVEEFQSITG
KGVKAKVNNEMYYVGSPNLFEELHQTIESTIKERITRMQTEGKTVMVLGTEKEILSLIAVADEMRETSKEVISKLNHIGI
ETVMLTGDNQRTAEAIGKQVGVSDIKADLLPEDKLNFIKELLGKHQSVGMVGDGVNDAPALAASSVGVAMGGAGTDTALE
TADIALMADDLSKLPYTIKLSRKALAIIKQNITFSLAVKLVALLLVMPGWLTLWIAIFADMGATLLVTLNSLRLLKVKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 2e-171 66
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 4e-171 64
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 4e-171 64

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lbuc_2431 YP_004399673.1 heavy metal translocating P-type ATPase BAC0298 Protein 2e-103 48
Lbuc_2431 YP_004399673.1 heavy metal translocating P-type ATPase BAC0092 Protein 1e-86 44