Gene Information

Name : Lbuc_1811 (Lbuc_1811)
Accession : YP_004399122.1
Strain : Lactobacillus buchneri NRRL B-30929
Genome accession: NC_015428
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1871796 - 1873349 bp
Length : 1554 bp
Strand : -
Note : PFAM: GMP synthase, C-terminal; Glutamine amidotransferase class-I, C-terminal; NAD/GMP synthase; TIGRFAM: GMP synthase, C-terminal; GMP synthase, N-terminal; HAMAP: GMP synthase; KEGG: lbr:LVIS_1759 GMP synthase

DNA sequence :
TTGGCAAACGTTGACTTATCAAGCTTCGATAAGATTTTAGTGCTGGATTTCGGTAGTCAGTATAACCAACTGATTACAAG
ACGGATCCGTGACTTAGGCGTATATTCTGAGCTTAAGTCCCACGCATTGTCCGCAAAACAGATCAAAGACATGAACCCCA
AGGGAATTATTTTCTCCGGGGGTCCAAATAGTGTGTACGAAGATGGCGCTTTGAAGGTTGATCCAGACATCTTCAAGCTG
GGAATTCCAATCTTGGGAATTTGTTATGGCATGCAGATTATGGCATATACCCTTAATGGTGAAGTCGAGAAGGCTTCCAA
TTCCGAGTACGGTCATGCTGATATTCAGATTACTTCTGATGATGCAGTTCTCTTCAAGGGAACCCCACGTGAGCAGCCAG
TCTGGATGAGTCACGGGGACTTGGTTAATGAAGTTCCTGAAGGCTTTGAGACAGTTGCCACCAGTCGTGACTGCCCAATT
TCTGCTATGCAGGATGTTGAGCGTAATTTGTATGGGATTCAGTTCCATGCTGAAGTTAGAAATACCAAGTATGGTAACGA
CATCTTGAAGAACTTTGCTTTCAACGTCTGCCATGCAGAGGCCAACTGGTCAATGGATGACTTCATTGATCTGCAGATTC
AACATATCAGAGAAGAAGTTGGCGACAAGAAAGTGCTGCTGGGTCTCTCTGGTGGAGTTGATTCAAGTGTTGTTGGTGTT
CTCTTGCACAAAGCAATTGGTAAGCAACTGACAAGTATTTTTGTTGACCACGGCTTGTTGCGCAAGAACGAAGCTGACCA
GGTCATGGATAGTTTGGTCGGCAAATTCGGCTTGAACATTATCAAAGTGGACGCTCAGGACCGCTTCCTTTCCAAGTTGA
AGGGTGTCACAGATCCTGAAAAGAAACGCAAGATTATTGGTAATGAGTTCATCCAAGTGTTTAACGATGAGGCCAGCAAG
CTTCACGGCATTGATTTCTTGGCCCAAGGCACGTTGTACACTGACGTGGTTGAGAGTGGAACTGATACTGCTCAGACAAT
CAAGTCTCACCATAACGTTGGCGGCCTGCCAGAAGACATGAAGTTTAAGCTGATCGAACCTTTGAACACGTTGTTCAAGG
ATGAAGCCCGGGCAATTGGTGAAAAATTGGGAATGCCAGAAACGCTTGTTTGGCGCCAGCCGTTCCCAGGACCAGGTCTC
GGCATTCGAGTGCTTGGTGAAGTGACTCCAGAAAAGCTGAAGATCGTTCGTGATAGCGATTGGGTCCTGCGGGATGAGAT
TGCTAAAGCTGGTTTAGACCGCGATATCTGGCAATACTTCACCGTTTTACCAGGCTTTAAGAGTGTTGGTGTCATGGGTG
ATGGTCGAACTTACGATTACACCGTTGCCATCCGAGCAGTGAACTCTGTTGACGGAATGACCGCTGACTTTGCACGGATT
CCATGGGATGTTCTGCAAAATGTCTCCACTCGGATCGTAAACGAAGTTGATGGCATTAACCGCGTAGTGTATGACATTAC
GAGCAAGCCACCGGCAACGATTGAATGGGAATAA

Protein sequence :
MANVDLSSFDKILVLDFGSQYNQLITRRIRDLGVYSELKSHALSAKQIKDMNPKGIIFSGGPNSVYEDGALKVDPDIFKL
GIPILGICYGMQIMAYTLNGEVEKASNSEYGHADIQITSDDAVLFKGTPREQPVWMSHGDLVNEVPEGFETVATSRDCPI
SAMQDVERNLYGIQFHAEVRNTKYGNDILKNFAFNVCHAEANWSMDDFIDLQIQHIREEVGDKKVLLGLSGGVDSSVVGV
LLHKAIGKQLTSIFVDHGLLRKNEADQVMDSLVGKFGLNIIKVDAQDRFLSKLKGVTDPEKKRKIIGNEFIQVFNDEASK
LHGIDFLAQGTLYTDVVESGTDTAQTIKSHHNVGGLPEDMKFKLIEPLNTLFKDEARAIGEKLGMPETLVWRQPFPGPGL
GIRVLGEVTPEKLKIVRDSDWVLRDEIAKAGLDRDIWQYFTVLPGFKSVGVMGDGRTYDYTVAIRAVNSVDGMTADFARI
PWDVLQNVSTRIVNEVDGINRVVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-166 69
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-166 69
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-166 69
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-120 49