Gene Information

Name : guaA (CbC4_2206)
Accession : YP_004396868.1
Strain : Clostridium botulinum BKT015925
Genome accession: NC_015425
Putative virulence/resistance : Unknown
Product : GMP synthase large subunit
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2396428 - 2397981 bp
Length : 1554 bp
Strand : -
Note : -

DNA sequence :
TTGGGAGGATACAGAATGGCTATAGAACGTGAATTAGTTTTAGTAGTAGATTTTGGCGGACAATATAACCAGCTTATAGC
AAGAAGAGTTAGAGAACATAATGTATATTGCGAAATAATTCCATATACTACTTCTATTGAAGATATTAAAAAGAAAAATC
CAAAAGCAATAATATTTACTGGGGGACCTAATAGTGTTTATGGTGAAGGAGCTCCAAGAATAGAAAAACAAATATTTGAT
TTAGAAATACCTGTACTTGGTATTTGTTATGGACATCAATTAACAGCTTATACTTTAGGTGGAAAAGTTGAAAGTCCTGA
TATAAGAGAATATGGAAAAACAGAAGTTAAAATAGACAATAAATCACCTTTATTCGATGGAATTAAGGAAGAAGATCAAT
CTTGGATGAGTCATACAGATTATGTATCGGAGATACCAGTAGGATTTAAAATAATAGCTACAACAGATCAATGTCCTGTA
GCTGCAATGGCAAACGAAGAAAGAAGAATATACGGGGTTCAGTTCCATCCAGAAGTTGAACATACATTATTTGGACAAAA
GATGCTTGGAAACTTCTTATTTAAAATAGCTAATCTAAAAGGTGATTGGTCAATGGCATCTTTTGCAGAAGAAAAAATCA
AAGCTATAAAAGAACTTGTTGGAGATAAAAAAGTACTTTGTGCATTATCAGGTGGAGTTGATTCATCAGTTGCAGCAGTA
CTTGTTCATAAGGCTATTGGTAAGCAATTAACTTGTGTATTTGTTGATCATGGTTTACTTAGAAAAGATGAAGGAGATCA
AGTTGAAGCTATATTTAAGAAACAATTTGATATGAATCTTATAAGAGTAAATGCAGCAGAAAGATTCCTTGGTAAATTAA
AAGGAGTAAGCGATCCTGAAACAAAGAGAAAGATAATTGGAGAAGAATTTATAAGAGTATTTGAAGAAGAAGCTGGAAAG
CTTGGACAAATAGATTTCTTAGTTCAAGGAACTATCTATCCAGATGTAGTTGAAAGTGGAACAAACACATCAGCTACAAT
AAAGAGTCACCATAATGTTGGAGGACTTCCAGAAGACATGCAATTCTCTTTAATAGAACCATTAAGAGAACTATTTAAAG
ATGAAGTTAGAGCTGTTGGAGAAGAACTTGGAATACCTCATAAATTAGTGTGGAGACAGCCATTTCCCGGACCAGGTCTT
GCAATAAGAGTCCTTGGTGAAATTACAGAAGAAAAACTAGAAATAACAAGAGAAGCAGATGCAATATTCAGAGAAGAAAT
TGCACTAGCAGGGCTTGAAGAAAAGATATGGCAGTACTTTGCATGCCTACCAAACATCCGATCAGTTGGTGTTATGGGGG
ATGAGAGAACATACTGTCATACAATAGCACTAAGAGCGGTAACATCAAGTGATGCTATGACTTCAGATTGGGCTAGAATT
CCATACGAAGTTTTAGATAAGGTAAGCCGTCGTATAGTTAATGAAGTTAAAGGAGTAAACAGAATTGTTTATGATGTAAC
TTCAAAACCACCATCAACTATTGAATGGGAATAG

Protein sequence :
MGGYRMAIERELVLVVDFGGQYNQLIARRVREHNVYCEIIPYTTSIEDIKKKNPKAIIFTGGPNSVYGEGAPRIEKQIFD
LEIPVLGICYGHQLTAYTLGGKVESPDIREYGKTEVKIDNKSPLFDGIKEEDQSWMSHTDYVSEIPVGFKIIATTDQCPV
AAMANEERRIYGVQFHPEVEHTLFGQKMLGNFLFKIANLKGDWSMASFAEEKIKAIKELVGDKKVLCALSGGVDSSVAAV
LVHKAIGKQLTCVFVDHGLLRKDEGDQVEAIFKKQFDMNLIRVNAAERFLGKLKGVSDPETKRKIIGEEFIRVFEEEAGK
LGQIDFLVQGTIYPDVVESGTNTSATIKSHHNVGGLPEDMQFSLIEPLRELFKDEVRAVGEELGIPHKLVWRQPFPGPGL
AIRVLGEITEEKLEITREADAIFREEIALAGLEEKIWQYFACLPNIRSVGVMGDERTYCHTIALRAVTSSDAMTSDWARI
PYEVLDKVSRRIVNEVKGVNRIVYDVTSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-163 65
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-163 65
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-163 65
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-143 56