Gene Information

Name : Alide2_1820 (Alide2_1820)
Accession : YP_004387721.1
Strain : Alicycliphilus denitrificans K601
Genome accession: NC_015422
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.3
Position : 1920982 - 1923384 bp
Length : 2403 bp
Strand : -
Note : TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: tin:Tint_3215 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase

DNA sequence :
ATGAGTTGCGGATCAAGCGGGTACGGTTGTGCTGATGCTCCCGTTCTCAAATCAGAAACACAGACCAGCGCCACTACCGG
GGTGGCGGTTGCCGTCTATCACATCGAGAACATGGACTGCCCCACGGAAGAAGCGCTGATCCGGGGCAAGCTGGGCGGCG
TGCCCGGCGTGGTGGAGCTCGATTTCAACCTGATGCGGCGCACCTTGACCGTGCGGCACACCCTGGCGTCGTTGGCCCCC
GTGGAACAAGCCTTGGCGGCTGTCGATATGCAGGCGGTGCGACAGGACGACCGCTCGGCGGTGCAGACCACCCGCCTTGC
CATCGCCAAGATGGATTGTCCGTCCGAGGAGGCGCTGATCCGCAGCAATCTCGCCACGCTGGCCGGTGTGATCGATCTCG
ACTTCAACCTGATGCAACGCACGCTCACCGTGCGCCATGCCCCAGCCGTGCTGCCTGACGTGCTGGGTGCTCTGCAATCG
CTCGGCTTCGAGGCCCAAGTGCTCGAAGAAGCCAACCGCACGCCTGCGTCATCAGCACCGGGGCAGACCACGACCCATTG
GTGGCCGCTCGGCATCTCGCTAGTCGCCGCTGTTGCGGCGGAGGCCGTGTACTGGCTCCAAGGCGGCAATCATTGGTCGG
TGATGGTTCTGGCTCTGGTCGCCATCCTCACCGGTGGCCTGTCCACCTACAAGAAAGGATGGATTGCCCTCAAGAACCGC
AACCTCAACATGAACGCCCTGATGTCGATTGCCGTCACCGGGGCCATGTTGATCGGGCACTGGCCGGAGGCGGCGATGGT
GATGGTGTTGTTCGCTTTGGCCGAGGTCATCGAGGCCAAGTCGCTGGACCGCGCCCGCAACGCCATCGCGGGGCTGCTCG
ATCTGGCCCCGGAGCGAGCCACGGTGCAACAGCCTGATGGCTCATGGCGCGAGGTGGATGCCAAGCAGGTTGCGATCGGC
AGCCGGGTGCGAGTGCGGCCTGGCGAACGCATCGCCCTCGATGGGGAGGTCGTAGAAGGCCGCTCGACCGTGAACCAAGC
GCCGATCACCGGGGAGAGTCTGCCCGTCGACAAGGGCCTAGGCGATCCCGTCTTTGCGGGTTCCCTCAACGAGTCAGGCT
CGTTCGAGTACCGTGTCACGGCGCTGGCGAACAACTCCACGCTGGCCCGCATCATTCATGCGGTGGAGGCCGCACAAGGC
AGCCGCGCGCCGACCCAGCGCTTCGTGGATCAGTTCGCGCGCTGGTACACGCCCGCCGTATTCGCCTTGGCCGTGGTCGT
CGCACTGGTGCCGCCGCTCTTTGTGGGAGCGGCATGGCTGGATTGGATCTATCGGGCGCTGGTTTTGCTGGTGATCGCCT
GCCCGTGCGCGCTGGTGATTTCGACACCCGTCAGCATCGTCAGCGGGTTGGCCGCAGCGGCACGCCACGGCATTCTCATC
AAGGGCGGCGTGTATTTGGAAGAGGGCCGCAAGCTGCGCTGGCTGGCCTTGGACAAGACCGGCACCATCACCCACGGCAA
GCCCGCGCAGACCGACTTCGTTGCCTTGGGTAACGCTTCGCCCCAGCACGCCCGTAGTCTCGCGGCCAGCCTGGCCAGCC
GCTCCGACCATCCGGTGTCCAAGGCAATCGCGCAAGCCGCCCTTGCCGACGGCGTGGCGCTGCGCGAAGTCGCGGAATTC
GCCGCATTGCCCGGCCGAGGCGTGCGCGGCGTGATCGACGGAGTGGCCTATCACCTCGGCAACCATCGGATGCTCGACGA
GCTGGGACATTGCTCCCCCGCAATGGAACAACGCATCACCGCACTGGAAGCCGAGGGTAAGACGGCGGTGATGCTGGTGG
AGCCCGAGGGCGTGCAGGCGCTCATGGCAGTGGCCGACACCATCAAGGACAGCAGCCGGAGCGCCGTGGCCGAACTGCAC
GCGCTGGGCATCCAGACCATGATGCTGACCGGCGACAACCCACACACCGCCAAGGCGATTGCCACACAGGCCGGGATCGA
CCGCGCACAAGGCAACCTGCTCCCCGATGACAAACTGCGCGAGATCGAAGCGCTTGCCCAGTCCGGCGGGGTCGGCATGG
TCGGTGATGGAATCAACGACGCTCCGGCGTTGGCTCGTGCCGACATTGGCTTCGCGATGGGCGCGGCGGGCACCGACACG
GCCATCGAGACGGCCGACGTGGCGCTGATGGACGATGACCTGCGCAAGATTCCGACCTTCGTGCGGCTGTCCCGCACCAC
GGCACAGGTGCTCACACAGAACATCGCGCTTGCGCTGGGCATCAAGGCCGTGTTCCTAGTGCTCACCTTCACCGGCCACG
CGACCATGTGGATGGCGGTGTTCGCCGACATGGGAGCTAGCCTGCTGGTGGTGGGCAATGGCTTGAGGCTGCTGCGCCGA
TGA

Protein sequence :
MSCGSSGYGCADAPVLKSETQTSATTGVAVAVYHIENMDCPTEEALIRGKLGGVPGVVELDFNLMRRTLTVRHTLASLAP
VEQALAAVDMQAVRQDDRSAVQTTRLAIAKMDCPSEEALIRSNLATLAGVIDLDFNLMQRTLTVRHAPAVLPDVLGALQS
LGFEAQVLEEANRTPASSAPGQTTTHWWPLGISLVAAVAAEAVYWLQGGNHWSVMVLALVAILTGGLSTYKKGWIALKNR
NLNMNALMSIAVTGAMLIGHWPEAAMVMVLFALAEVIEAKSLDRARNAIAGLLDLAPERATVQQPDGSWREVDAKQVAIG
SRVRVRPGERIALDGEVVEGRSTVNQAPITGESLPVDKGLGDPVFAGSLNESGSFEYRVTALANNSTLARIIHAVEAAQG
SRAPTQRFVDQFARWYTPAVFALAVVVALVPPLFVGAAWLDWIYRALVLLVIACPCALVISTPVSIVSGLAAAARHGILI
KGGVYLEEGRKLRWLALDKTGTITHGKPAQTDFVALGNASPQHARSLAASLASRSDHPVSKAIAQAALADGVALREVAEF
AALPGRGVRGVIDGVAYHLGNHRMLDELGHCSPAMEQRITALEAEGKTAVMLVEPEGVQALMAVADTIKDSSRSAVAELH
ALGIQTMMLTGDNPHTAKAIATQAGIDRAQGNLLPDDKLREIEALAQSGGVGMVGDGINDAPALARADIGFAMGAAGTDT
AIETADVALMDDDLRKIPTFVRLSRTTAQVLTQNIALALGIKAVFLVLTFTGHATMWMAVFADMGASLLVVGNGLRLLRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 71
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 2e-118 46
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-118 46
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 8e-119 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Alide2_1820 YP_004387721.1 heavy metal translocating P-type ATPase BAC0298 Protein 0.0 75
Alide2_1820 YP_004387721.1 heavy metal translocating P-type ATPase BAC0100 Protein 1e-59 41