Gene Information

Name : Alide2_1747 (Alide2_1747)
Accession : YP_004387651.1
Strain : Alicycliphilus denitrificans K601
Genome accession: NC_015422
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1846291 - 1848306 bp
Length : 2016 bp
Strand : +
Note : SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain; TIGRFAM: DNA topoisomerase III, bacterial-type; KEGG: mpt:Mpe_A2342 DNA topoisomerase III; PFAM: DNA topoisomerase, type IA, central; Toprim domain; DNA t

DNA sequence :
ATGCGCGTGTTCCTGTGCGAGAAGCCGTCCCAGGGCAAGGACATTGCCCGTGTGCTGGGCGCAGGCCAACGCGGCAACGG
CTGCTACAGCGGCGCGGGTGTCGTCGTGACCTGGTGCATCGGTCATCTGGTGGAGGCGGTTCCGCCCGAAGGCTACGGCG
AGCAATACAAGCGCTGGGCCATCGAGCAACTCCCCATTCTTCCTGAGCGTTGGCGTGTCGAGCCCAAGTCGGCGACCGCA
GCGCAATTCAAGGTCGTGCAGCAGCTCGTCGCCAAGGCGGGCGAGCTGGTGATTGCGACCGACGCCGACCGCGAGGGCGA
GATGATCGCCCGCGAGATCATCGACCTATGCAGCTACCGCGGGCCGATTCAGCGCCTGTGGCTGTCGGCGCTCAACGATG
TGTCGATCCGCAAAGCGCTGGGTGCGCTCAAGCCGTCCGCCGAGACGCTGCCGCTGTATTTCTCCGCACTCGCCCGATCG
CGCGCCGACTGGCTGATCGGGATGAACCTGAGCCGCTTGTTCACACTGCTGGGGCGTCAGGCCGGCTATACGGGCGTGCT
GTCGGTGGGGCGCGTGCAGACGCCGACGCTGAAGTTGGTCGTGGATCGTGATCGCGAGATCGCGCGATTCGTCTGCGTAC
CGTTCTGGGCCATCGAGGTTGCGCTTTCGCATGCAGGCCAGTCCTTCGTCGCAAGCTGGACGCCGCCGCAAGGCAGCACC
GACGATGCGGGCCGCTGCCTGCAACAGCCGGTGGCGCAGCAGGCCGTCGAGCGCCTGCGCACGGCCGGCGCCGCCCAGGT
GCGGTCGGTAGAAACCGAGCGCGTGCGCGAAGGGCCGCCGCTGCCGTTCGACTTGGGCACGCTGCAGGAGGTGTGCTCCA
AACAGTTGGGCCTCGATGTGCAGGAGACGCTGGACATCGCCCAGGCGCTGTACGAGACGCACAAGGCGACAACGTATCCG
CGCTCGGATTCGGGCTACCTGCCCGAGAGCATGCTGGCCGAGGTACCGACCGTACTCGACAGCATGGTCAAGACCGACCC
CAGCCTGCGGCCGCTGATCGAGCGCCTGGATCGCCAACAGCGCTCGCGTGCATGGAACGACGGCAAGGTGTCGGCTCACC
ACGGCATCATCCCGACGCTGGAGCCCGCCAACCTGTCGGCCATGAACGAGAAGGAACTGGCCGTCTACCGGCTGATCCGC
GCCCATTACCTCGCGCAGTTCCTCCCGCACCATGAGTTCGACAGGACGGTGGCGCAGTTCTCATGCGGCAGTCAGTCGCT
GGCGGCCGTGGGCAAGCAGATCGCCGTCATCGGCTGGCGTGAGGTGCTGGCGACGCCGGGGCCGGACGATGCCGATGGCG
AGGATGCGCAGCGCAGCCAGGTGCTGCCCGCCCTGCATGCGGGCCTGTCCTGCCCGGTCGGAAAGGTGGATCTCAAGGCG
CTGAAGACGCTGCCGCCCAAACCCTACACGCAGGGCGAGCTGATCAAGGCCATGAAGACCGTCGCCAAGTTCGTGACCGA
CCCGCGCCTGAAACAGAAGCTGCGAGATACCACCGGCATCGGCACCGAGGCGACACGCGCCAACATCATCAACGGTCTGA
TCGGTCGCGGCTACCTGGTCAAGAAAGGCCGTGCCGTCCGCGCTTCCGACGCGGCATTCACGCTCATCGACGCGGTGCCC
TCGGCCATCGCCGACCCCGGCACTACGGCGGTGTGGGAGCACGCGCTCGACATGATCGAGGCCGGCCAGATGGCGTTGGA
CACCTTCATCGAGAAGCAGGCCGCGTGGGTCGGTCAGCTCGTGCAGCAGTACCGCGGCGCGACGCTCTCGCTCAAGCTGC
CGCCGGCGCCGGCCTGCCCGCAGTGCGGCGCGCCGATGCAGCAGCGCACGGGCAAGAGCGGCGCGTTCTGGTCCTGCTCG
CGCTACCCGGACTGCAAGGGCACGCTGCCGATCGAGTCCCCGACGGGCCGGCGCAGCGCACCGCGCAAGCGGCGCGCTGC
CTCCAAGGCGTCCTGA

Protein sequence :
MRVFLCEKPSQGKDIARVLGAGQRGNGCYSGAGVVVTWCIGHLVEAVPPEGYGEQYKRWAIEQLPILPERWRVEPKSATA
AQFKVVQQLVAKAGELVIATDADREGEMIAREIIDLCSYRGPIQRLWLSALNDVSIRKALGALKPSAETLPLYFSALARS
RADWLIGMNLSRLFTLLGRQAGYTGVLSVGRVQTPTLKLVVDRDREIARFVCVPFWAIEVALSHAGQSFVASWTPPQGST
DDAGRCLQQPVAQQAVERLRTAGAAQVRSVETERVREGPPLPFDLGTLQEVCSKQLGLDVQETLDIAQALYETHKATTYP
RSDSGYLPESMLAEVPTVLDSMVKTDPSLRPLIERLDRQQRSRAWNDGKVSAHHGIIPTLEPANLSAMNEKELAVYRLIR
AHYLAQFLPHHEFDRTVAQFSCGSQSLAAVGKQIAVIGWREVLATPGPDDADGEDAQRSQVLPALHAGLSCPVGKVDLKA
LKTLPPKPYTQGELIKAMKTVAKFVTDPRLKQKLRDTTGIGTEATRANIINGLIGRGYLVKKGRAVRASDAAFTLIDAVP
SAIADPGTTAVWEHALDMIEAGQMALDTFIEKQAAWVGQLVQQYRGATLSLKLPPAPACPQCGAPMQQRTGKSGAFWSCS
RYPDCKGTLPIESPTGRRSAPRKRRAASKAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 80
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 79
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 64
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 8e-162 51
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 1e-161 51
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 1e-161 51
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 5e-163 51
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 5e-163 50