Gene Information

Name : Alide2_1187 (Alide2_1187)
Accession : YP_004387107.1
Strain : Alicycliphilus denitrificans K601
Genome accession: NC_015422
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1235608 - 1238211 bp
Length : 2604 bp
Strand : +
Note : TIGRFAM: Chaperonin ClpB; PFAM: ATPase, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; KEGG: dia:Dtpsy_2550 ATP-dependent chaperone ClpB; SMART: ATPase, AAA+ type, core

DNA sequence :
ATGCGTCTTGACAAACTCACCACGAAATTCCAGGAAGCCCTGTCCGATGCCCAGTCGCTCGCGCTGGGCCATGACAACGC
CTATATCGAGCCCGTGCACCTGCTGGCCGCCATGCTGCGCCAGGAGGACGGCCCGCGCGCGCTGCTGGAGCGCGCCGGCG
CCAACGTGCCCGGCCTGCTGAAGGCGTCCGAGGCCGCCATCAAGCGCCTGCCACAGGTGCAGGGCCATGACCAGGTGCAG
GCCAGCCCCGAGCTGGGCCGCGTGCTGCAGGCTACCGAGAAGGAGGCCATCCAGCGCGGCGACCAGTTCATCGCAAGCGA
GCTGTTCCTGCTGGCCCTCGTGGACAGCAAGGGCGAGGCAGCGCAGATCGCCAAGGACAACGGCCTCACGCGCAAGAGCC
TGGAAGCCGCCATCGACGCCGTGCGCGGCGGCCAGAAGGTGGACAGCGCCGAGGCCGAGGGCCAGCGCGAGGCCCTGAAG
AAATACACCCTGGACCTGACCGAGCGCGCGCGCCAGGGCAAGCTCGACCCCGTGATCGGGCGCGACGACGAGATCCGCCG
CGCCATCCAGGTGCTGCAGCGGCGCAGCAAGAACAACCCCGTGCTGATCGGCGAGCCCGGCGTGGGCAAGACCGCCATCG
TGGAGGGCCTGGCCCAGCGCATCGTCGCGGGCGAGGTGCCCGAGACGCTCAAGAACAAGCGCGTGCTGGTGCTGGACATG
GCGGGCCTGCTGGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAGCGCCTGAAGTCCGTGCTCAAGGAAGTGGCGCAGGA
CGAGGGCCGCATCATCCTGTTCATCGACGAGATCCACACCATGGTCGGCGCCGGCAAGGCCGAGGGCGCGATCGACGCGG
GCAATATGCTCAAGCCCGCCCTCGCGCGCGGCGAGCTGCACTGCATCGGCGCGACCACGCTGGACGAATACCGCAAGTAC
ATCGAGAAGGACGCGGCGCTGGAACGGCGCTTCCAGAAAGTGCTGGTCGAGGAGCCCTCGGTGGAGGACACCATCGCCAT
CCTGCGCGGCCTGCAGGTGCGCTACGAGGCGCACCATGGCGTGGACATCACCGACCCGGCCATCGTCGCCGCGGCGGAAC
TCTCCCACCGCTACATCACCGACCGCTTCCTGCCCGACAAGGCCATCGACCTGATCGACGAGGCGGCTGCGCGCATCAAG
ATCGAAATCGACTCCAAGCCCGAGGCGCTGGACAAGCTCGAACGCCGCATGATCCAGCTCAAGATCGAGCGCGAGGCGAT
GAAGAAGGAGACCGACGAGGCCTCGCAGAAGCGCCTGCAGCTCATCGAGGAAGAGCTGGCCAACGCCGAGCGCGAGTACG
CCGACCTGGAAGAGGTCTGGAAGGCCGAGAAGGCCAGCGCCCAGGGCAGCGAGCAGATCCGCAAGGACATCGACGCGATC
CGCATCCAGATCGAGGACCTGAAGCGCAAGGGCGACTACAACCGCGTGGCTGAGCTGCAGTACGGCAAGCTGCCCGAGCT
GGAGAAGCGCCTGAAGGAGGCGCAGGACAGCGAGGCCGGCGGCGGCGCGCCCAGGCACCAGCTGCTGCGCACCCACGTGG
GCGCGGAGGAGATCGCCGAGGTGGTGAGCCGCGCCACCGGCATCCCCGTGGCCAAGATGATGCAGGGCGAGAAGGACAAG
CTGCTACACATGGAGGAAAAGCTGCACGAGCGCGTGGTGGGCCAGGACGAGGCGATCTCCGCCGTGGCCAACGCCATCCG
CCGCTCGCGCTCGGGCCTGTCGGACCCCAACAGGCCGCTGGGCAGCTTCCTGTTCCTCGGCCCCACGGGCGTGGGCAAGA
CCGAGCTGTGCAAGGCGCTGGCGGGCTTCCTGTTCGACAGCGAAGAGCACATGGTGCGCATCGACATGAGCGAGTTTATG
GAAAAGCATAGCGTTGCGCGCTTGATTGGTGCGCCTCCGGGCTATGTCGGCTATGAAGAGGGCGGCTATCTAACCGAGGC
CGTGCGGCGCAAGCCCTATTCCGTGCTGCTGCTCGACGAGGTGGAGAAGGCCCATCCCGACGTGTTCAACGTGCTGCTGC
AGGTGCTCGACGACGGGCGTCTGACCGACGGCCAGGGCCGCACCGTGGACTTCAAGAACACGGTGATCGTCATGACCAGC
AACATCGGCTCGCCGCTGATCCAGGCCATGGTGGGGCAGGACGCCGAGGACATCAAGGAAGCGGTGTGGGGGGAACTCAA
GAGCCATTTCCGACCCGAATTCCTGAACCGCATCGACGAGACGGTGGTGTTCCACGGCCTCGACGCGAAACACATCGAAG
CCATTGCCCGCATTCAGTTGCGGCTGCTGGAGGCGCGGCTTGCGAAGATGGATCTCTCGCTGCAAGTGTCTCCGGCCGCC
ATGGGCGAGCTGGCCAAGGTGGGGTTCGATCCGGTGTTCGGTGCGCGGCCGCTCAAGAGGGCGATCCAGCAGCGTATCGA
GAACCCGCTGTCCAGGCTGCTGCTCGAAGGGCGCTATCCGCCCAAGAGCGTGATTCCGGTGGACGTCGATCCTGTGAAGG
ATCCAGGGGTATTCCACTTTGGCGAGGCCCGCGCGGCGGGCTGA

Protein sequence :
MRLDKLTTKFQEALSDAQSLALGHDNAYIEPVHLLAAMLRQEDGPRALLERAGANVPGLLKASEAAIKRLPQVQGHDQVQ
ASPELGRVLQATEKEAIQRGDQFIASELFLLALVDSKGEAAQIAKDNGLTRKSLEAAIDAVRGGQKVDSAEAEGQREALK
KYTLDLTERARQGKLDPVIGRDDEIRRAIQVLQRRSKNNPVLIGEPGVGKTAIVEGLAQRIVAGEVPETLKNKRVLVLDM
AGLLAGAKYRGEFEERLKSVLKEVAQDEGRIILFIDEIHTMVGAGKAEGAIDAGNMLKPALARGELHCIGATTLDEYRKY
IEKDAALERRFQKVLVEEPSVEDTIAILRGLQVRYEAHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAARIK
IEIDSKPEALDKLERRMIQLKIEREAMKKETDEASQKRLQLIEEELANAEREYADLEEVWKAEKASAQGSEQIRKDIDAI
RIQIEDLKRKGDYNRVAELQYGKLPELEKRLKEAQDSEAGGGAPRHQLLRTHVGAEEIAEVVSRATGIPVAKMMQGEKDK
LLHMEEKLHERVVGQDEAISAVANAIRRSRSGLSDPNRPLGSFLFLGPTGVGKTELCKALAGFLFDSEEHMVRIDMSEFM
EKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVLLLDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFKNTVIVMTS
NIGSPLIQAMVGQDAEDIKEAVWGELKSHFRPEFLNRIDETVVFHGLDAKHIEAIARIQLRLLEARLAKMDLSLQVSPAA
MGELAKVGFDPVFGARPLKRAIQQRIENPLSRLLLEGRYPPKSVIPVDVDPVKDPGVFHFGEARAAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-106 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 5e-103 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 4e-103 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Alide2_1187 YP_004387107.1 ATP-dependent chaperone ClpB VFG2076 Protein 2e-111 45
Alide2_1187 YP_004387107.1 ATP-dependent chaperone ClpB VFG2084 Protein 1e-106 43