Gene Information

Name : Lbuc_2375 (Lbuc_2375)
Accession : YP_004385902.1
Strain :
Genome accession: NC_015420
Putative virulence/resistance : Resistance
Product : arsenical pump membrane protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 6148 - 7443 bp
Length : 1296 bp
Strand : +
Note : KEGG: lpl:pWCFS103_13 arsenical pump membrane protein; TIGRFAM: Arsenical pump membrane protein; PFAM: Arsenical pump membrane protein

DNA sequence :
ATGCAAGTCTTTTTTGCCGTTGGAATTTTCTTACTCACATTATTATTCGTTATCTGGCAACCTAGAGGATTATCAATTGG
ATGGACAGCCATTGGTGGTGCAATTTTAGCATTATTGTTTGGCGTGGTGAGTTTTAAAGATGTTGGAACAGTTACCGGAA
TTGTCTGGAATGCCACCTTATCTTTCGTGGCTATTATTCTGATTTCACTCATTTTAGATCAAATCGGATTTTTTGAATGG
GCCGCCTTACACATGGCTCGCTGGGCAAACGGTCACGGTATTCGCATGTTTATTTTGGTGACCACCTTAGGCGCCGTCGT
TGCTGCCCTTTTTGCTAATGATGGGGCTGCTCTGATTCTTACCCCCATTGTTTTAGCAATGGTTCGTGCCTTACACTTTG
ATGAAAAGCAAGTTTTCCCTTTTATTATTGCCAGTGGCTTTATTGCCGATACCACTTCTTTACCAATGATTGTTAGTAAC
TTGGTAAATATTGTCTCTGCAGACTTTTTTGGAATTTCCTTTTCAGCGTATGCGTTAAGAATGTGGATTCCTGATCTATT
TTCGCTGTTAGGTAGTATTGGTATCCTGTATCTTTACTTTCGAAAAGCATTGCCACGAAAATTTGATGCCACTCAGGTTG
CGGAACCCAGTTCTGCACTAAAAGATCAGCGACTTTTCAAGTTTTCATGGGTCGTCTTAATCCTCCTATTGATTGGTTAC
TTTAGTAGCGGTTTCTTAGGAATCCCCGTCTCCTTTATCGCACTGAGTATTGCGGCTATTTTTCTGATAGTTGGTCAAAG
AAGTTCCCATGTTAATGCGATGGCAGCGATTAAAGGAGCTCCTTGGAACATTGTCTTTTTCTCAATCGGTATGTATGTCG
TAGTCTACGGCCTTCAGAACGTTGGTCTAACAACATTATTATCAGGTGTCATTACCGAAATCGCAAAAGGTGGTCGGTTT
GCTGCCACAATGGGCATGGGCTACTTAGCAGCACTTTTATCGTCATTAATGAATAACATGCCGACCGTCATGATTAATGC
ACTATCAATCAAAGGCGCTGACGTTTCAGGGCTCATCCATCATACGTTAGTGTACGCAAACATAATCGGCTCAGATTTGG
GACCTAAGATTACCCCAATTGGCTCTTTGGCTACATTAGTCTGGCTACATGTGTTAGCTCAAAAGGGAGTTAAAATTAAA
TGGGGGACTTATTTTAAAATTGGAATTGTAACCACGATCCCAGTGTTGTTTATTACCCTATGTGGCCTCTGGTTATCATT
ATCGATTTTTGGTTAG

Protein sequence :
MQVFFAVGIFLLTLLFVIWQPRGLSIGWTAIGGAILALLFGVVSFKDVGTVTGIVWNATLSFVAIILISLILDQIGFFEW
AALHMARWANGHGIRMFILVTTLGAVVAALFANDGAALILTPIVLAMVRALHFDEKQVFPFIIASGFIADTTSLPMIVSN
LVNIVSADFFGISFSAYALRMWIPDLFSLLGSIGILYLYFRKALPRKFDATQVAEPSSALKDQRLFKFSWVVLILLLIGY
FSSGFLGIPVSFIALSIAAIFLIVGQRSSHVNAMAAIKGAPWNIVFFSIGMYVVVYGLQNVGLTTLLSGVITEIAKGGRF
AATMGMGYLAALLSSLMNNMPTVMINALSIKGADVSGLIHHTLVYANIIGSDLGPKITPIGSLATLVWLHVLAQKGVKIK
WGTYFKIGIVTTIPVLFITLCGLWLSLSIFG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 7e-130 66
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 2e-126 66
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 3e-129 66
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 5e-105 56

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lbuc_2375 YP_004385902.1 arsenical pump membrane protein BAC0574 Protein 2e-127 66
Lbuc_2375 YP_004385902.1 arsenical pump membrane protein BAC0575 Protein 5e-128 65
Lbuc_2375 YP_004385902.1 arsenical pump membrane protein BAC0576 Protein 1e-105 57
Lbuc_2375 YP_004385902.1 arsenical pump membrane protein BAC0578 Protein 1e-105 57
Lbuc_2375 YP_004385902.1 arsenical pump membrane protein BAC0031 Protein 7e-102 56
Lbuc_2375 YP_004385902.1 arsenical pump membrane protein BAC0577 Protein 1e-105 56