Gene Information

Name : Lbuc_2374 (Lbuc_2374)
Accession : YP_004385901.1
Strain :
Genome accession: NC_015420
Putative virulence/resistance : Resistance
Product : arsenite-activated ATPase ArsA
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0003
EC number : 3.6.3.16
Position : 4372 - 6105 bp
Length : 1734 bp
Strand : +
Note : KEGG: lpl:pWCFS103_12 arsenical pump-driving ATPase; TIGRFAM: ATPase, anion-transporting

DNA sequence :
ATGATGGAAAAGTATTCGCCACAAGAGATTAATTTAACCAAGTACCTATTTTTTACCGGCAAGGGTGGGGTTGGCAAAAC
CACGGTTGCCAGTGCCACTGCAATTAGCTTAGCTGATGCTGGTCACCGAGTTATGATCGTTTCCACTGATCCAGCTAGTA
ACTTGCAGGACGTTTTTAAAGTTAGTTTAACCAATCAGCCAAAGTCGATTCCAAACATTTCCGGTTTGTTTGCTGCCAAC
TTTGATCCGGTCATTGCTGCGAACGAGTATCGCGAGCAGGTTATTCAACCTTATCGAGGCGTGTTGCCCAAAGAAGCCAT
TCAGAATATGGCTGAACAATTATCAGGCTCGTGTACGGTTGAAATTGCTGCATTTAATGAATTTGCCAACTTTCTAACTA
GTTCCAAGATTAATCAGCAATTTGACTATATTATTTTTGATACCGCGCCGACCGGCCATACCTTAAGAATGCTGCAATTG
CCTTCTGCTTGGAGTAATTACCTGGATAAGAATGATCGTGGTGCATCCTGTCTCGGCCAACTAGCTGGCTTAAATGATAA
GAAAGCTATGTATCAAAAAGCGGTTGAAACTTTAGGCAATCCTCAAGCGACGACTTTGTTTTTAGTTACCCGACCACAAA
AAGGCGCCCTTCTGGAGGCACAACGCGCTTCACATGATTTGGCAGCCTTAAACATTAAGAACCAGCAACTAATCATTAAC
GGTATCTTAAATCAGCCAACCGATGCAGTTTCTCAGACTATTTTTAAACAACAGCAAGCTGATTTGCAGAATATGCCAGT
CACTTTAGACCAGCTACCCAAGTTAGCAATCCCATTGCGAGCATACAACGTATTGGGATTAGCTAATTTACGACTACTAT
TGAAAGATCAGCAGCCGCAAATCACTGAGGAACCGGTTACTGCTAGTCACTTTCCTGATCTGGATGTTGTCGTGAAGAAT
TTAGTGCAGTCAAATAAAAAAATTATCTTCACCATGGGCAAAGGTGGCGTTGGTAAAACAACCGTTGCCGTTCAAATTGC
CCAAAAGATAGCTGCTCAACACAAAACCGTGCACTTGGCTACCACTGACCCAGCTGATCATTTGAAATACTTCAAAATCA
CAAGTCCGCTGATCAAGGTGAGCCATATTGATGAGAAAAAGTCTTTAAAAGAATATCAAAACGAAGTTCTCACTACTGCT
AAAAAGACCATGAAGTCTAATGATGTTGATTATGTCGCTGAAGATTTGCGTTCACCATGTACTCAAGAAATTGCTGTCTT
CCGAGCTTTTGCTGAGTTAGTCGCCCAAAATGATAGTGACGTCGTTGTGGTTGATACGGCTCCGACTGGTCATACACTCT
TACTGTTAAACTCGACCCAAAGCTATGCTCAAGAAGTTGCCCATACCTCCGGCAGCGTCCCACAAGCAGTCGTTAATCTG
TTACCAAGACTACAAGATCCTAAGCAAACTGAAATTGTTATGGTAACGCTACCAGAAACCACGCCGGTTTATGAATCAAT
GCGGTTAGATGACGATTTGAAGCGAGCCAGTCTAGCTCATACTTGGTGGGTGGTCAACCAAAGTATGTTGGCAACTCAAA
CCACTGATCCATGTTTGCTGGCTCGAGTGCAAAGCGAAGTTAAATGGATTGATCAGGTAAAAGAGCTTTCGAATAATCAT
TTTGCTGTTATGCAATGGCAACCAAATTACGAAAAAACGCTTTTAACGGTTTAA

Protein sequence :
MMEKYSPQEINLTKYLFFTGKGGVGKTTVASATAISLADAGHRVMIVSTDPASNLQDVFKVSLTNQPKSIPNISGLFAAN
FDPVIAANEYREQVIQPYRGVLPKEAIQNMAEQLSGSCTVEIAAFNEFANFLTSSKINQQFDYIIFDTAPTGHTLRMLQL
PSAWSNYLDKNDRGASCLGQLAGLNDKKAMYQKAVETLGNPQATTLFLVTRPQKGALLEAQRASHDLAALNIKNQQLIIN
GILNQPTDAVSQTIFKQQQADLQNMPVTLDQLPKLAIPLRAYNVLGLANLRLLLKDQQPQITEEPVTASHFPDLDVVVKN
LVQSNKKIIFTMGKGGVGKTTVAVQIAQKIAAQHKTVHLATTDPADHLKYFKITSPLIKVSHIDEKKSLKEYQNEVLTTA
KKTMKSNDVDYVAEDLRSPCTQEIAVFRAFAELVAQNDSDVVVVDTAPTGHTLLLLNSTQSYAQEVAHTSGSVPQAVVNL
LPRLQDPKQTEIVMVTLPETTPVYESMRLDDDLKRASLAHTWWVVNQSMLATQTTDPCLLARVQSEVKWIDQVKELSNNH
FAVMQWQPNYEKTLLTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0111 YP_252026.1 arsenical pump-driving ATPase Not tested SCCmec Protein 7e-104 45
arsA2 YP_001007632.1 arsenical pump-driving ATPase Not tested YAPI Protein 7e-95 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lbuc_2374 YP_004385901.1 arsenite-activated ATPase ArsA BAC0572 Protein 8e-94 45
Lbuc_2374 YP_004385901.1 arsenite-activated ATPase ArsA BAC0030 Protein 5e-94 45
Lbuc_2374 YP_004385901.1 arsenite-activated ATPase ArsA BAC0571 Protein 7e-96 44