Gene Information

Name : Marky_0911 (Marky_0911)
Accession : YP_004367767.1
Strain : Marinithermus hydrothermalis DSM 14884
Genome accession: NC_015387
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 886647 - 888161 bp
Length : 1515 bp
Strand : +
Note : COGs: COG0519 GMP synthase PP-ATPase domain/subunit; HAMAP: GMP synthase; InterProIPR004739:IPR001674:IPR022955:IPR000991:IPR 011063; KEGG: opr:Ocepr_0850 gmp synthase (glutamine-hydrolyzing); PFAM: GMP synthase, C-terminal; glutamine amidotransferase cla

DNA sequence :
ATGAGCGTAGTCATCCTCGACTTCGGCTCGCAGTACACCCGTTTGATCGCTCGCCGCGTGCGGGAGCTGCGGGCGTACTC
GGTGATCCTGCCCGGCACCGCTTCCCTTGAGGAAATCCAAGCGCAAAACCCCCAGGCGATCATCCTTTCCGGTGGGCCGA
GCTCGGTCTTCGATCCGGGGGCGCCGAGACCGCACTCGGGTGTGCTCGAGATGGGCCTGTCCATCCTCGGCATCTGTTAC
GGGATGCAGTACCTGGCCCAGCATTACGGGGGGCGGGTGGAGCGCGCCGGCCGCCGCGAGTACGGCAAGGCCGTCCTCAC
GCGCTACGAGGGGCCGTTGTTTGACGGGCTGGCCGGGGAGGTGCAGGTCTGGATGAGCCACTCGGACGCGGTCACCGAGC
TGCCCCGGGGCTGGCGGGTAGTGGCCGAGACCGAGGAGAACCCGGTCGCGGCGATCCAGTCCCCGGACGGCCGCGTCTTT
GGGGTGCAGTTCCACCCCGAGGTGGTGCACACTCCTAAGGGCGCGGAGATCCTGGAGAACTTCCTCGAGGCAGCCGGCGT
GGCGCGGGACTGGACGCCGGAGCACACCTTAGAGAGCCTCGTCCGGGAGGTGCGGGAGCGCGTGGGGGAGGAGCGCGTGT
TGCTCGCGGTTTCGGGCGGGGTGGATTCCAGCACCCTCGCGCTGCTGTTGGCCCGCGCGGGCGTGGATCACGTCGCGGTC
TTCGTGGATCACGGGTTGTTGCGCCTGGGGGAGCGGGCCGAGGTCGAGCATGCCCTGAAACCCCTTGGGGTGAACCTCGT
TACGGTGGACGCCTCCGAGCGTTTCTTGGCGGCGCTGGAGGGGGTGACCGACCCCGAGGCCAAGCGCAAGATCATCGGGC
GGGAGTTCGTTGAGGTCTTCAAAGAGAAGGCGCGGGAGCTAGGGCCCTTTACCTTCCTCGCCCAGGGCACGCTCTACCCG
GACGTGATCGAGTCCGCCGGAGGCGCGGGCGCGGCGAACATCAAAAGCCACCATAACGTGGGCGGCCTCCCGAAGGACCT
GGGGTTTGAGCTGCTGGAGCCCTTCCGCTACCTCTTCAAGGACGAGGTGCGGGAGCTGGCCCTTCTCCTGGGGCTTCCGG
ACACGATCCGCTTACGCCACCCCTTCCCGGGACCGGGCCTGGCGATCCGCATCCTGGGCGAGGTCACCCGGGAGAAGCTC
GAGATCCTACGCCGCGCGGACGACCTCTTCATCAGCACCCTCAAGGCCTGGGGCCTCTACCACGAGACCTGGCAGGCCCT
GGCGGTCCTGACCCCCGTGCGTTCGGTGGGGGTGGTGGGGGACGAACGGCACTACGGGTACGTCCTCGCCCTGCGCGCGA
TCACCAGCGTGGACGGCATGACCGCGGACTGGGCCCGGCTGCCCCTCGAGTTCCTCGACGAGGTGGCCCGCAAGATCACC
CGCCAGGTCCCGGAGATCGGGCGGGTGGTGTACGACGTGACCTCCAAGCCGCCCGCGACGATCGAGTGGGAGTAG

Protein sequence :
MSVVILDFGSQYTRLIARRVRELRAYSVILPGTASLEEIQAQNPQAIILSGGPSSVFDPGAPRPHSGVLEMGLSILGICY
GMQYLAQHYGGRVERAGRREYGKAVLTRYEGPLFDGLAGEVQVWMSHSDAVTELPRGWRVVAETEENPVAAIQSPDGRVF
GVQFHPEVVHTPKGAEILENFLEAAGVARDWTPEHTLESLVREVRERVGEERVLLAVSGGVDSSTLALLLARAGVDHVAV
FVDHGLLRLGERAEVEHALKPLGVNLVTVDASERFLAALEGVTDPEAKRKIIGREFVEVFKEKARELGPFTFLAQGTLYP
DVIESAGGAGAANIKSHHNVGGLPKDLGFELLEPFRYLFKDEVRELALLLGLPDTIRLRHPFPGPGLAIRILGEVTREKL
EILRRADDLFISTLKAWGLYHETWQALAVLTPVRSVGVVGDERHYGYVLALRAITSVDGMTADWARLPLEFLDEVARKIT
RQVPEIGRVVYDVTSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-120 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-114 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-114 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-114 51