Gene Information

Name : Marky_0634 (Marky_0634)
Accession : YP_004367494.1
Strain : Marinithermus hydrothermalis DSM 14884
Genome accession: NC_015387
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 613703 - 614836 bp
Length : 1134 bp
Strand : +
Note : COGs: COG0626 cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: fri:FraEuI1c_6724 Cys/Met metabolism pyridoxal-phosphate-dependent protein; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: cystathionine

DNA sequence :
ATGGAAGAAACCCTAGGCTTTGCGACACTGGCAGTGCACGCCGGTCAGGAACCGGACCCCGAGACCGGCGCGGTCATTCC
GCCCATCCACCTCAGCTCCACCTTCCAGCAGCCCGCACCCGGCGAGCCCCGGCGCTACGAGTACAGCCGCACGCAAAACC
CCACGCGTGAGGCCCTCGAGGCCCAGATCGCGGCCCTCGAGGGCGCGCGTTGGGGGTTGGCGTTTGCGAGCGGGATGGCC
GCGGTGGACGCGGTGGCGCACCTGCTGCGCCCGGGGGACCGCGTGGTCTTGATGAACGACGTGTACGGCGGCACCTACCG
TTACTTCGCCCGCGTGCTCGCGGACTGGGGGGTGACGCCGGACTTCCGCGATCTCACGGACCCTGAGACGTGGGCGTTCG
CGGGGGCGCGGATGGTCTGGGTTGAGACCCCCACGAACCCCTTCCTGCGCGTCGTGGACCTCGCTGCCGTCGCCGAAGCC
GCGCGCAAAGCCGGGGCGTTGCTTGTGGTGGACAACACCTTCGCGAGCCCCTACCTGACCCGTCCCCTCGAGCTCGGTGC
GGACCTCGTGGTGCACAGCGCGACCAAGTACCTGGGGGGGCACTCGGACCTGGTGCTCGGCGTGGTCCTCGGGCGGGACG
AGGCGTTGCGCGAGCGGTTGGCGTTCTACCAGAACTCGGTGGGGGCGGTGCCCGGACCGTTTGAGGCGTGGTTGTGCAGC
CGGGGCTTGAAGACCCTGGCGCTACGCATGGAGCGTCACTCGGAGACCGCCCAGGCCCTCGCCGCGTGGCTTGCGGCGCA
TCCACGGGTGCGCCGGGTGCACTACCCGGGCTTGCCCACCCACCCGAACCACGCGGTCGCGGCGCGGCAGATGCGGCGGT
TTGGAGGGATGCTCTCGATCGAGCTCGAGTCCAAGGAGGCCGCGGTGCGTTTTGTGAAGGCGTTGCGGTTGTTCACGCTG
GCCGAGTCCTTGGGGGGGGTGGAGTCCCTCGTGAGCATTCCGGGCTTGATGACGCACGCTTCCTTGAAAGGCACGCCGTT
TGAGGTGCCGGAGCGCTTGGTGCGCCTCAGTGTGGGTGTGGAGGACCTCGAAGACCTCCGTCGCGACCTCGAGGCGGCGC
TGGAACGGGTTTGA

Protein sequence :
MEETLGFATLAVHAGQEPDPETGAVIPPIHLSSTFQQPAPGEPRRYEYSRTQNPTREALEAQIAALEGARWGLAFASGMA
AVDAVAHLLRPGDRVVLMNDVYGGTYRYFARVLADWGVTPDFRDLTDPETWAFAGARMVWVETPTNPFLRVVDLAAVAEA
ARKAGALLVVDNTFASPYLTRPLELGADLVVHSATKYLGGHSDLVLGVVLGRDEALRERLAFYQNSVGAVPGPFEAWLCS
RGLKTLALRMERHSETAQALAAWLAAHPRVRRVHYPGLPTHPNHAVAARQMRRFGGMLSIELESKEAAVRFVKALRLFTL
AESLGGVESLVSIPGLMTHASLKGTPFEVPERLVRLSVGVEDLEDLRRDLEAALERV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-66 48
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-67 48
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-53 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Marky_0634 YP_004367494.1 cystathionine gamma-lyase BAC0207 Protein 4e-57 46