Gene Information

Name : Marky_0590 (Marky_0590)
Accession : YP_004367450.1
Strain : Marinithermus hydrothermalis DSM 14884
Genome accession: NC_015387
Putative virulence/resistance : Virulence
Product : two component transcriptional regulator, winged helix family
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 563769 - 564443 bp
Length : 675 bp
Strand : +
Note : COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: msv:Mesil_0841 two component transcriptional regulator, winged helix family; PFAM: Signal transduction r

DNA sequence : 
ATGGCACGGGTCCTCCTGGTGGAAGACGAGGAAAGCGTCCGCGTCGGCCTTCGGCTGGGGTTAAGGCAGGCCGGGTTCAC
GGTCCTCGAGGCCGCCACCGCTGCCGAGGGGTGGGCTCAGCTCGAAGGGTGCGACGTGGTGGTGCTGGACTGGATGCTTC
CGGACGAGCCGGGGATCCGGTTCCTCGAGCGCCTGCGCCGCACGCCGCGGTTCGAGGGGCTTCCGGTTCTGATGCTCACC
GCGCGCGCCGCGGAGGCCGACCGGGTGGAGGGGCTGACGCGCGGGGCGGACGATTACCTGGTGAAGCCCTGCTCGCTTCC
GGAACTCGTCGCGCGCCTCAAGGCCCTCTTGCGCCGCGCGGGGCGGCGGCGGGTGGTGGAACGGCCGGGGCTGGTGCTGG
ACCTGGAGCGCATGGAGGTGCGCGTGGAGGGGCGGCCCGTCGAACTGACCCGGAGGGAGTTCGACCTGCTCGCGCACCTC
GCACGCCACGCGGGCCGGGTCTTTACCCGTGAGGAGTTGCTGGAGCAGGTGTGGGGACCGGACTTCTTCGGGACCGCCCG
CACCGTGGACCAGCACGTGGCGCAACTGCGCGAGAAGCTAGGGGACGCGCCGAACGCACCGCGCTTCATCGAAACGGTCC
GGGGCAAAGGGTACCGCTTCAAGGAAGGAGGCTAG

Protein sequence : 
MARVLLVEDEESVRVGLRLGLRQAGFTVLEAATAAEGWAQLEGCDVVVLDWMLPDEPGIRFLERLRRTPRFEGLPVLMLT
ARAAEADRVEGLTRGADDYLVKPCSLPELVARLKALLRRAGRRRVVERPGLVLDLERMEVRVEGRPVELTRREFDLLAHL
ARHAGRVFTREELLEQVWGPDFFGTARTVDQHVAQLREKLGDAPNAPRFIETVRGKGYRFKEGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
armR AAN62112.1 putative response-regulator ArmR Not tested PAGI-2(C) Protein 2e-15 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Marky_0590 YP_004367450.1 two component transcriptional regulator, winged helix family BAC0197 Protein 1e-23 43
Marky_0590 YP_004367450.1 two component transcriptional regulator, winged helix family NC_012469.1.7686381. Protein 1e-23 41
Marky_0590 YP_004367450.1 two component transcriptional regulator, winged helix family NC_002952.2859905.p0 Protein 3e-26 41
Marky_0590 YP_004367450.1 two component transcriptional regulator, winged helix family NC_009782.5559369.p0 Protein 2e-26 41
Marky_0590 YP_004367450.1 two component transcriptional regulator, winged helix family NC_002951.3237708.p0 Protein 2e-26 41
Marky_0590 YP_004367450.1 two component transcriptional regulator, winged helix family NC_007622.3794472.p0 Protein 3e-26 41
Marky_0590 YP_004367450.1 two component transcriptional regulator, winged helix family NC_003923.1003749.p0 Protein 2e-26 41
Marky_0590 YP_004367450.1 two component transcriptional regulator, winged helix family NC_002758.1121668.p0 Protein 2e-26 41
Marky_0590 YP_004367450.1 two component transcriptional regulator, winged helix family NC_009641.5332272.p0 Protein 2e-26 41
Marky_0590 YP_004367450.1 two component transcriptional regulator, winged helix family NC_013450.8614421.p0 Protein 2e-26 41
Marky_0590 YP_004367450.1 two component transcriptional regulator, winged helix family NC_007793.3914279.p0 Protein 2e-26 41
Marky_0590 YP_004367450.1 two component transcriptional regulator, winged helix family NC_002745.1124361.p0 Protein 2e-26 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Marky_0590 YP_004367450.1 two component transcriptional regulator, winged helix family VFG1389 Protein 4e-22 42