Gene Information

Name : Marky_0004 (Marky_0004)
Accession : YP_004366879.1
Strain : Marinithermus hydrothermalis DSM 14884
Genome accession: NC_015387
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 4050 - 5471 bp
Length : 1422 bp
Strand : +
Note : COGs: COG0469 Pyruvate kinase; InterPro IPR001697:IPR015793:IPR015795; KEGG: opr:Ocepr_0004 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; PFAM: Py

DNA sequence :
ATGCATTCTAAACGCACCAAGATCGTCGCCACCATCGGCCCGGCCTCGCGCAAGCCCGAGGTACTCGAGGCGATCCTCGA
GGCCGGTGTGGACGTGGTGCGGCTGAACTTCAGCCACGGCACTCCCGAGGACCACCGCCGCACGGTCGAGGCGGTACGCG
AGCTTTCTGAACGCCTCGGGAAGACCGTGGCGGTGCTGCAGGACCTGCAGGGGCCCAAGATCCGCGTGGGGCGCTTCAAG
GACGGGGCGGTCGAACTCGAGGTCGGCCAGGCCTTCATCCTGACCACCGAGGAGGTCGAGGGGGACGAGAAGCGGGTCTC
CGTCTCGTACAAGGGCCTTCCCGGGGACGTGGAGGAAGGCCAGGTCCTGCTCCTCGACGACGGTAACCTCCGCTTGCGCG
TCACCCGCGTCGAGGCCGACGCGATCCACACGGTCGTCGAGGTCGGGGGGCGCCTGTCCAACAACAAAGGGATCAACATC
CCCGGCCGGGACCTCTCCATCCCCGCCCTCACCGACAAGGACATCGAGGACCTCGCGCTCGGCGTGGAGCTCGGGGTTGA
CTGGGTAGCCATGAGTTTCGTGCGGAGCCGCGACGACCTGCTCCTCGCCCGGCACTACCTGACCCGGTACGGCTCGAGCG
CCAAGCTCATGGCCAAGATCGAAAAACCCAGCGCGGTGGAGCGCTTCTCCGAGATCCTGGAGGAGGCCGACGGGATCATG
GTGGCCCGCGGGGATCTGGGCGTGGAGATGCCGCCCGAGGAGGTGCCCATCGTGCAGAAGCGCCTGATCGAGCGGGCGCG
CGCCGCGGGCAAGCCGGTGATCACCGCCACGCAGATGCTCGAGTCCATGATTCAGAACCCGCGCCCGACACGCGCAGAGG
CCTCCGACGTAGCCAACGCGATCTTCGACGGGACGGACGCGGTGATGCTCTCGGCGGAGACCGCGGCGGGCAGCCACCCG
GTCGCCGCGGTGGAGATGATGCGCCGGGTGGCCCGCGTGGTCGAAGGGGCGCCTGAGTTCATCGATCGGCTGGTCGGGAT
GCGCCCTGAACCGAACCACACCACGCAGGATGCGGTGGCCCTCGCGGCCTGCGAGGTGGCCGAGTCCCTGCCCGCCCGGT
GCATCGTCGTCTTTACCGCGACCGGGTCGTCCGCATGGCGGGTGGTACGGAACCGGCCGCGGGTGCCGGTTCTGGGCTTG
ACACCGAACCCGCGGGTGCGGAACCAGATGGCCCTTGCTTTCGGGCTCACCCCGATGCTCGCGCCGGACGCGCACAACAC
CGACGAGATGGTGCGCATCGCGGTGGATCACGCTAAGGCCGCGGGGCTCGCGGACCCCGGGGACCGCATCGTGATCACCG
CGGGCGTGCCCTTTGGCGGGCGGGGCACCACAAACATGGTCTGGGTGGAGCGGGTGCGCTGA

Protein sequence :
MHSKRTKIVATIGPASRKPEVLEAILEAGVDVVRLNFSHGTPEDHRRTVEAVRELSERLGKTVAVLQDLQGPKIRVGRFK
DGAVELEVGQAFILTTEEVEGDEKRVSVSYKGLPGDVEEGQVLLLDDGNLRLRVTRVEADAIHTVVEVGGRLSNNKGINI
PGRDLSIPALTDKDIEDLALGVELGVDWVAMSFVRSRDDLLLARHYLTRYGSSAKLMAKIEKPSAVERFSEILEEADGIM
VARGDLGVEMPPEEVPIVQKRLIERARAAGKPVITATQMLESMIQNPRPTRAEASDVANAIFDGTDAVMLSAETAAGSHP
VAAVEMMRRVARVVEGAPEFIDRLVGMRPEPNHTTQDAVALAACEVAESLPARCIVVFTATGSSAWRVVRNRPRVPVLGL
TPNPRVRNQMALAFGLTPMLAPDAHNTDEMVRIAVDHAKAAGLADPGDRIVITAGVPFGGRGTTNMVWVERVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-73 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-73 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-72 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-73 43
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 1e-64 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Marky_0004 YP_004366879.1 pyruvate kinase VFG0479 Protein 3e-73 43