Gene Information

Name : Marky_1980 (Marky_1980)
Accession : YP_004368820.1
Strain : Marinithermus hydrothermalis DSM 14884
Genome accession: NC_015387
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1992547 - 1995174 bp
Length : 2628 bp
Strand : +
Note : COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR002302:IPR015413:IPR013155; KEGG: ttj:TTHA0161 leucyl-tRNA synthetase; PFAM: valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; Aminoacyl-tRNA synthetase, class I (M); PRIAM: Valine--tRNA

DNA sequence :
ATGGAGAAGTACAACCCGCACGCGATCGAGCCCAAGTGGCAAGCGTACTGGCAGGAGAAGGGCCTGATGAAGGCCAAGGA
GGAGGGCGAGAAGCAGTACGTCCTCATGATGTTCCCCTACCCCTCCGGTGACCTGCACATGGGCCACCTGAAGAACTACA
CCATGGGGGACGTGCTGGCCCGCTTCAAGAAGCAGCAGGGCTACACCGTGCTGCACCCCATGGGCTGGGACGCGTTCGGC
CTGCCCGCCGAGAACGCGGCCCTTAAGTTCGGCGTGCACCCCGCGGAGTGGACCTTCAAGAACATCGCCTCGGCCAAGGA
GTCCCTCCGCCTGATGGGCATCCTCTACGACTGGGACCGCGAGGTCACCACCTGCACGCCCGAGTACTACCGCTGGAACC
AGTGGATCTTCCTCAAGATGTACGAAAAGGGCCTCGTCTACCGCGCGAAGGGCCTGGTGAACTGGTGCCCCAAGTGCCAG
ACCGTCCTCGCGAACGAGCAGGTGGTGGACGGCCGCTGCTGGCGGCACGAGGACACCCTGGTCGAGAAAAAAGAGCTCGA
GCAGTGGTACCTGCGGATCACCGCCTACGCCGACCGCCTCCTCCAGGACCTCGAGCAGCTCACGGGCTGGCCGGAGAAGG
TCAAGGCCATGCAACGCGCCTGGATCGGCCGGAGTGAAGGCGCGGAGATCGCGTTCCCCGTCAAGGGCCGGGACGTGAAG
ATCCCCGTCTTCACCACCCGGCCCGACACCCTCTTCGGCGCGACCTTCCTGGTCCTCGCTCCTGAGCACCCGATGCTCCT
CGAGCTTACCGCCCCCGAGCGGCGCGCGGAGGTCGAGGCGTACGTGGCGGCCGCCAAGCAAAAGACCGAGCTCGAGCGCG
AGGCCCTGGGGCGCGAGAAGACCGGGGTGTTCACCGGGGCGTACGCGATCAACCCCGCGACCGGCGAGGAAATCCCCATC
TGGACCGCGGATTACGTGCTGTACGGGTACGGGACCGGCGCGATCATGGCGGTGCCCGCGCACGACCAGCGGGACTTCGA
GTTTGCGCGGCGGTTCAACCTGCCCGTCCGGGTGGTGATCCAGCCCGCTGAGGGCGGGCTCGCCGAGCCGCTCGAGGCCG
CCTACGAGGAGCCGGGCGTCATGGTGAACTCCGGCCCCTTCGACGGCACGCCGAGCGTGGAGGGTAAGGGCCGGGTCATC
CGCTGGCTCGAGGAAAAGGGCCTGGGGCGGGCCCGGGTCACGTACCGCATGCGGGACTGGTTGATCAGCCGGCAGCGGTA
CTGGGGCACGCCGATCCCCATGATTCACTGCGAGGCCTGCGGGATCGTGCCCGTGCCGTACGAGGACCTGCCCGTGGTGC
TTCCGGAGATCCAGGACGTGGAGGAGATCCGCCCCAAGGGGAAGAGCCCCCTCGAGGCGCACCCCGAGTTCTACGAGACC
ACCTGCCCCCACTGCGGCCGGCCGGCGCGGCGGGACACCGACACCATGGACACCTTCTTCGACTCCTCGTGGTACTACCT
GCGCTACGCCGACCCGCATAACGACCGGCTGCCCTTCGATCCCGAGAAGGCCGATTTCTGGCTGCCCGTGGACCAGTACA
TCGGGGGGATCGAGCACGCGGTGCTGCACCTGCTGTACTCCCGGTTCTTCACCAAGTTCCTGCACGACATCGGCATGGTG
CGGGTGGAGGAGCCGTTCAAGGGGCTCTTCACGCAGGGCATGGTGATGGGCTGGACGGACTACGGTCCCGTCCAGGTGGA
GGGCGAGACCGTACGGCTGAGCGAGGAGGCCCGCGTCCGGCTGGACCTCGAGTCGGGCACGCTCACCAAGGCCGAGCTCG
CCAAGATGGGGGCGGAGCTGCGCGCGCACGAGGACGGCACGACGCACCTGTGGAAGCCCGCGGTGATGTCCAAGTCCCTG
GGGAACGGCGTGATGGTGGGGCCTTTCGTGAAGGAGCAGGGCGCGGACATCGCGCGCATCACGATCCTCTTCGCCGCGCC
GCCCGAGAACGACATGGTCTGGACGGAGGAGGGCGTTTCGGGCGCGTGGCGCTTTTTGAACCGCGTCTGGCGGCGGTTCG
CGGAGGATAAGGACGCCCTAACCACCCTCGAGGACGCCTTCGATCCCGCTGCGCTTTCCGGGGCGGACCGGGCGCTGTAC
CGGGCGCTGCACCGCACCTTGAAGAAGGTCGGGGAGGACACGGAGAACCTGCGCTTCAACACCGCCATCGCCGCGCTGAT
GGAGCTGTTGAACGCCCTTTACGAGTACCGCCATAAGCACGCGCCGAGCCCCGTCTACAAGCGGGCGGTGCGGTACTACC
TGCAGATGCTCGCGCCGTTCGCGCCGCACCTCGCGGAGGAGGTCTGGCACTGGCTCGATGCGCGTTCGGTCTTCGAGGTC
CCGTGGCCTGAGGTGGACGAGGACGCGCTCGTGGAGGACACCTTCGAGCTGGTGGTTCAGGTGAACGGCCGGGTGCGCGG
CCGCGCGGTGCTGCCCACGAACGTCGGTGAGGAGGAAGCCAAGCAGGCCGCGAAGGCCATCGAGAATGTGCGGCGGCACC
TCGAGGGCCGCACGATCGTGAAGGAGATCTACGTGCCCGGGAAGCTGCTCAACATCGTGGTGAAGTAA

Protein sequence :
MEKYNPHAIEPKWQAYWQEKGLMKAKEEGEKQYVLMMFPYPSGDLHMGHLKNYTMGDVLARFKKQQGYTVLHPMGWDAFG
LPAENAALKFGVHPAEWTFKNIASAKESLRLMGILYDWDREVTTCTPEYYRWNQWIFLKMYEKGLVYRAKGLVNWCPKCQ
TVLANEQVVDGRCWRHEDTLVEKKELEQWYLRITAYADRLLQDLEQLTGWPEKVKAMQRAWIGRSEGAEIAFPVKGRDVK
IPVFTTRPDTLFGATFLVLAPEHPMLLELTAPERRAEVEAYVAAAKQKTELEREALGREKTGVFTGAYAINPATGEEIPI
WTADYVLYGYGTGAIMAVPAHDQRDFEFARRFNLPVRVVIQPAEGGLAEPLEAAYEEPGVMVNSGPFDGTPSVEGKGRVI
RWLEEKGLGRARVTYRMRDWLISRQRYWGTPIPMIHCEACGIVPVPYEDLPVVLPEIQDVEEIRPKGKSPLEAHPEFYET
TCPHCGRPARRDTDTMDTFFDSSWYYLRYADPHNDRLPFDPEKADFWLPVDQYIGGIEHAVLHLLYSRFFTKFLHDIGMV
RVEEPFKGLFTQGMVMGWTDYGPVQVEGETVRLSEEARVRLDLESGTLTKAELAKMGAELRAHEDGTTHLWKPAVMSKSL
GNGVMVGPFVKEQGADIARITILFAAPPENDMVWTEEGVSGAWRFLNRVWRRFAEDKDALTTLEDAFDPAALSGADRALY
RALHRTLKKVGEDTENLRFNTAIAALMELLNALYEYRHKHAPSPVYKRAVRYYLQMLAPFAPHLAEEVWHWLDARSVFEV
PWPEVDEDALVEDTFELVVQVNGRVRGRAVLPTNVGEEEAKQAAKAIENVRRHLEGRTIVKEIYVPGKLLNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-160 46