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Name : Marky_1263 (Marky_1263) Accession : YP_004368113.1 Strain : Marinithermus hydrothermalis DSM 14884 Genome accession: NC_015387 Putative virulence/resistance : Virulence Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : 1.2.1.8 Position : 1258796 - 1260316 bp Length : 1521 bp Strand : + Note : COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR011985; KEGG: msv:Mesil_2311 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain; PRIAM: betaine-aldehyde dehydrogenase; SPTR: 5-carbox DNA sequence : ATGAGGCGAGCCTTTGATCCGGCCTTCATCGAGTCGGTGCGCGAGCGCATCGCGAAGACCACGGTGCCGCACTTCATCGG GAACGCCTTCGTACCCGGCGCGCGCGGCGAGACCTTCGAGACCCTGGACCCGGCCACGAACCGGGTGCTGGGGCGCGTCT ACCGCGGGCACGCGGAGGACGTCGCCAAGGCCGTGCAGGCCGCCCGCGCGGCGTTCGAGGGCCCGTGGGGGCGCACCAAG GCCAAGGAGCGCAAGCGCTACCTCCTCAAGATCGCCGAGCTTTTAGAGAAGCACGCGGACGAGCTCGCGGTGATCGAGTG CCTCGACGCCGGTCAGGTGCTCAAGATCGTGCGCAAACAGGTCGCGCGCGCGGCGGAGAACTTCAGCTTCTACGCGGAGT ACGCCGAGCGCGCCATGGACGGGCACACCTACCCTGTGGACCAGGACTGGGTCAACTACACCGTCCGCGTGCCCGTGGGC GTCACCGGGATCATCACCCCCTGGAACGCCCCCCTGATGCTCTCCACCTGGCGGATCGCGCCCGCACTCGCCGCCGGGAA CACCGTGGTCCTCAAACCCGCGGAATGGTCCCCCCTCACGGCCTGGAAGCTCGCGGAGATCATCCAGGAGGCCGACCTGC CCCCCGGCGTGTTCAACGTGGTCCAGGGGTTCGGGGAGGAGGCCGGCGCGCCCCTCGTCGCGCACCCCGACGTGCCCCTC ATCTGCCTCACCGGCGAGACCACGACCGGCCAGATCGTGATGCGCAACGGGGCCGACCACCTCAAGCGCCTCTCCCTCGA GCTCGGCGGCAAAAGCCCCGCGATCATCTTCGAGGACGCGGACCTCGAGCGCGCCCTGGACGCCACCGTCTTCCAGATCT ACTCCTTCAACGGCGAGCGCTGCACGGCCAACTCCCGCGCCCTCATCCAAGAGTCCATCTTCGAAGCCTTCGTCGCACGA CTCGCGGAACGCGCCCAAAACATCCGGGTGGGCCACCCCCTCGACCCCGAGACCGAGGTCGGCCCCCTGATCCACCCCGA GCACCTCGAGCGCGTCCTGGGCTACATCCAGATCGGCCAGGAAGAGGGGGCGCGGCTCGTGGCGGGCGGCCAGCGCCTCG GCACGGAGGGGAACTACGTCGCCCCCACCCTGTTCGTGGGGGAAAACCACATGCGGATCGCGCAGGAGGAGATCTTCGGG CCCGTACTCGTCGCCATCCCCTTCAAAGACGAAGCCGACGCCCTAAAGAAAGCCAACGACACAAAGTACGGCCTGGCCGC CTACGTCTGGACCCGGGACGTGACCCGCGCGCACCGCGTGGCCCTCCGGCTCGAGGCCGGCATGACCTGGATCAACAGCC ACAACGTGCGGCACCTGCCCACGCCCTTCGGCGGCATGAAGTTCTCCGGCACGCACCGCGAGGGCGGGCAGTACGCCCTC GAGTTCTACACCGAGATCAAGAACATCGCCGTGCCGCTCGGCGAGCACCCCATCCCCAAGTTCGGCAAAAAGGAGGCGTA A Protein sequence : MRRAFDPAFIESVRERIAKTTVPHFIGNAFVPGARGETFETLDPATNRVLGRVYRGHAEDVAKAVQAARAAFEGPWGRTK AKERKRYLLKIAELLEKHADELAVIECLDAGQVLKIVRKQVARAAENFSFYAEYAERAMDGHTYPVDQDWVNYTVRVPVG VTGIITPWNAPLMLSTWRIAPALAAGNTVVLKPAEWSPLTAWKLAEIIQEADLPPGVFNVVQGFGEEAGAPLVAHPDVPL ICLTGETTTGQIVMRNGADHLKRLSLELGGKSPAIIFEDADLERALDATVFQIYSFNGERCTANSRALIQESIFEAFVAR LAERAQNIRVGHPLDPETEVGPLIHPEHLERVLGYIQIGQEEGARLVAGGQRLGTEGNYVAPTLFVGENHMRIAQEEIFG PVLVAIPFKDEADALKKANDTKYGLAAYVWTRDVTRAHRVALRLEAGMTWINSHNVRHLPTPFGGMKFSGTHREGGQYAL EFYTEIKNIAVPLGEHPIPKFGKKEA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hpaE | AAO17179.1 | HpaE | Not tested | tcd island | Protein | 2e-104 | 51 |
| ORF SG19 | AAN62241.1 | putative aldehyde dehydrogenase | Not tested | PAGI-3(SG) | Protein | 4e-75 | 43 |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 2e-79 | 42 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-80 | 41 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-80 | 41 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-80 | 41 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 4e-80 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Marky_1263 | YP_004368113.1 | 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase | VFG0082 | Protein | 6e-80 | 42 |
