Gene Information

Name : Tresu_0490 (Tresu_0490)
Accession : YP_004364737.1
Strain : Treponema succinifaciens DSM 2489
Genome accession: NC_015385
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 540357 - 542156 bp
Length : 1800 bp
Strand : -
Note : COGs: COG0469 Pyruvate kinase; InterPro IPR015793:IPR015795:IPR001697; KEGG: ssm:Spirs_0059 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; PFAM: Py

DNA sequence : 
ATGCTTACAAGAAAAACAAAAATCGTATGCTCAATCGGACCTGCCTGCGACAACGATGACACAATCCGCGAAATGATAAA
AGCAGGAATGAACATAGCCAGATTCAACTTTTCGCACGGAACTTATGACTGGCACAAGCAAGCAATGGACAGGGTTCGCA
GAGTTTCTGCAGAAATAGATGTACCTGTTGCAATTCTTTTGGACACAAAAGGTCCCGAAATCCGCACTGGACTTATAGAC
GGCACAAACAACATCAATCTTTCCGCAGGTGAAACCGTAATTGTTACAACAGACGACTGCACTTGCGTAAATGCTTCGGA
AGGTAAGCCGTGCAGAATTTCAATTTCATGGAAAGAAGCCACAAAAAAAGTTTCATCGGGAATAAAAATCTTAATAGCCG
ATGGACTGATTGAACTTGTTGTTCAGAAAGTTGAAGGCGAAGAAATTATATGCAAGGCTTCAAACGCCGGAACTTTTGGA
AGCAGAAAAAATGTAAACTTAATCGGAGTTCATGCCGGGCTTCCAATCATGTCAGACAAAGACAAGGAAGATTTAAAGTT
CGGGGCAACACAGGACATTGATTTTGTTGCGGCGAGCTTTGTAAGTTTCCCGGAAGAAGTTGTACAGATTAAAGAATACT
TAAAATCTGTAGGCGCAAAAGCCCGTGTCATTGCAAAAATCGAAAATGAAGAAGGCTTAAACAACATTGAAAAAATCACA
CGCGAGGCAGATGGAATAATGGTTGCGCGCGGAGATTTGGGAGTCCAGCTTCCTACAGAAAGAATTCCGCTCGCGCAAAA
AGCCATTATAAGATGCTGCCATACCGCCGGAAAACCTGTAATCACGGCAACGCAAATGCTCGATTCAATGATTGTAAATC
CGCGGCCTACAAGAGCAGAGCTTACTGATGTTGCAAACGCAATTTTTGACGGAACAGATGCGCTCATGCTTTCCGGGGAA
ACTGCTGGCGGAAAATATCCAGTTGAATCTGTAAAGACAATGGCGCTGATTGCCCGCACAACAGAAGATTCTCTTGAATA
CAAAGAGCACATGAGAAAAATAGATTCCGACTATGTTCCCGGAACAGAAGTAGGACACATGGTTGCACACAGCGCATACA
AACTTTCAAAGAACATAAAGGCAAAAGCAATAATAATTCCGACACTGCATGGAAACACTGCAAGAATGATTGGAAGTTTT
CGTCCAGAGCAAATTGTAATTGCTGTAACTCCAAATAAAAAAGTTCAGCGTCAGCTTATGATTCAGTGGGGTGTAACTCC
GGTTCTTTGCAGAATCGCAGGAGATTCAGACATGATGATTCAGAATGCTGTAAAACTTGCAATTGAAAACAACCTCGTAA
AACTTTCAGACAGAGTTGTTGTGTGCGCAGGAATTCCGCTTTCAAGTCCGCTTATGGTAAACACAATCCGAGTACTTGTT
GTTGGAAACATAATTGCAAGAGGAACTTCATTCGGATTCTGCAACAGTGAAAAACAAAAAATCTGCGGAAGAATAATCCA
CGCAGAAGACATTGTTGAAATCCGCGACACTGTAAAACTGAACCACAAAACAATTCTTGTTTGCGAAAGAATAACAGAAG
ACCTCATTCCGGTATTAAGAATTATAGACGGAGTTATTTCAGAATCCGGAAGCGACTTGCAAGAGGAAAACCTGAAACTT
GTAAATCCGAACCTTGTCTATATACAGAATGTTCCCGACGCCTGCAAAATTCTTGAGGACAATCTCTCTGTTTCCATAGA
CGGAGAGCAGGGACTTATTTACGAGGGAGCAATCTGCTAA

Protein sequence : 
MLTRKTKIVCSIGPACDNDDTIREMIKAGMNIARFNFSHGTYDWHKQAMDRVRRVSAEIDVPVAILLDTKGPEIRTGLID
GTNNINLSAGETVIVTTDDCTCVNASEGKPCRISISWKEATKKVSSGIKILIADGLIELVVQKVEGEEIICKASNAGTFG
SRKNVNLIGVHAGLPIMSDKDKEDLKFGATQDIDFVAASFVSFPEEVVQIKEYLKSVGAKARVIAKIENEEGLNNIEKIT
READGIMVARGDLGVQLPTERIPLAQKAIIRCCHTAGKPVITATQMLDSMIVNPRPTRAELTDVANAIFDGTDALMLSGE
TAGGKYPVESVKTMALIARTTEDSLEYKEHMRKIDSDYVPGTEVGHMVAHSAYKLSKNIKAKAIIIPTLHGNTARMIGSF
RPEQIVIAVTPNKKVQRQLMIQWGVTPVLCRIAGDSDMMIQNAVKLAIENNLVKLSDRVVVCAGIPLSSPLMVNTIRVLV
VGNIIARGTSFGFCNSEKQKICGRIIHAEDIVEIRDTVKLNHKTILVCERITEDLIPVLRIIDGVISESGSDLQEENLKL
VNPNLVYIQNVPDACKILEDNLSVSIDGEQGLIYEGAIC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-81 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-80 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-80 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-79 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tresu_0490 YP_004364737.1 pyruvate kinase VFG0479 Protein 6e-81 44