Gene Information

Name : Tresu_1125 (Tresu_1125)
Accession : YP_004365334.1
Strain : Treponema succinifaciens DSM 2489
Genome accession: NC_015385
Putative virulence/resistance : Virulence
Product : FliI/YscN family ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1196174 - 1197523 bp
Length : 1350 bp
Strand : +
Note : COGs: COG1157 flagellar biosynthesis/type III secretory pathway ATPase; InterPro IPR005714:IPR003593:IPR004100:IPR000194; KEGG: tde:TDE1218 flagellum-specific ATP synthase FliI; PFAM: ATPase, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1

DNA sequence :
ATGGAAAATTTTTTTGATAAATACATTCATAGCATAGAACGGATTGAACCCATAAAATATACCGGCTCTGTCATAGGAGT
AAAAGGTCTTATGATAGAAAGCAAAGGTCCTCGTTCTGTAATTGGCGAAATCTGCACAATACATATTCCAAGCATTCAAA
GTTCCGTTCTTGCGGAAGTTGTTGGTCTTGAAGATTCTTCTGTACGTCTTATGGCTTACGGAGAGACAAAGGGAATTGAA
GTTGGCTGTGAAGTTGTTGCTTCAGGGCACGTTTTGGAAGTACCTGTTGGATTATCGCTTTTGGGACGCGTAATAGACGC
AACTGGAAAGCCTTATGACGGAAAAGGCGAGATTTTCCCTGAGGCATATTACCCGGCTCTTGCATCTCCTCCGAATCCAA
TGGAACGCAAGCCGATTGACAAGCGCATTGTTACTGGAGTTCGCGCTATTGATGGAATTCTCACAGTTGGAAAAGGCCAG
CGTCTTGGAATTTTTGCAGGCTCAGGAGTTGGAAAATCAACGCTTCTTTCAATGATTGCGCGGAATACAAATGCTGATAT
AAACGTAATTGGTCTTATCGGAGAACGTGGACGCGAAGTCATGGACTTTATAAAGCGCGACTTGGGAGAAGAAGGACTTA
AACGTTCTGTTCTTGTTGTTGCAACTAGCGATCAGCCTTCCATTTCAAGATTGAGAGCCGCTTATGTTACAACTGCCATA
GCTGAATATTTCCGCGACCAAGGGAAGGACGTTATGCTGATGTTTGACAGCGTAACTCGTTTTGCCCATGCGCAAAGAGA
AATTGGTCTTGCAACCGGCGAGCCTCCTGCGCAAAGAGGTTATCCTCCGAGCGTTTTTGATATGCTGCCTAAGCTTCTTG
AGCGCACAGGAACAAATGATAAAGGAAGCATTACCGCCTTTTATACAGTCCTTGTTGACGGCGACGATATGGATGAGCCT
ATTGCTGATAAAGTGCGCGGAACTTTAGACGGACATATTGTTTTGCAGCGTTCCCTTGCAGCGCGTCAGCATTATCCTGC
AATCGATATGCTTACAAGCATCAGCCGTCTTTCAAAGCGCGTTTCTGGAACTTGCACAAAAAAAGCAGTGCAGCGTGTGC
GCCGTTGGATTTCTGTTTATTCAGAGCAGGAAGAAATGATAAATGCCGGTGTTTACCAAAAAGGTTCTTCCCCGGAAATT
GATGAAGCCATTGACCATCATCAGGCTGTTGAAGAGTTTTTGTGCCAGGAAGAAAACTGCCATATTACAATTGAAGACAC
GTTGAAGTCTCTTTCTGAATTAAGTGGAATTGAAATTCCTGAAGCCGAATATTCAGAGTCTCCTGCTTGA

Protein sequence :
MENFFDKYIHSIERIEPIKYTGSVIGVKGLMIESKGPRSVIGEICTIHIPSIQSSVLAEVVGLEDSSVRLMAYGETKGIE
VGCEVVASGHVLEVPVGLSLLGRVIDATGKPYDGKGEIFPEAYYPALASPPNPMERKPIDKRIVTGVRAIDGILTVGKGQ
RLGIFAGSGVGKSTLLSMIARNTNADINVIGLIGERGREVMDFIKRDLGEEGLKRSVLVVATSDQPSISRLRAAYVTTAI
AEYFRDQGKDVMLMFDSVTRFAHAQREIGLATGEPPAQRGYPPSVFDMLPKLLERTGTNDKGSITAFYTVLVDGDDMDEP
IADKVRGTLDGHIVLQRSLAARQHYPAIDMLTSISRLSKRVSGTCTKKAVQRVRRWISVYSEQEEMINAGVYQKGSSPEI
DEAIDHHQAVEEFLCQEENCHITIEDTLKSLSELSGIEIPEAEYSESPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 9e-99 51
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-94 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 7e-95 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-95 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-95 50
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-94 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-95 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-95 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-91 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-91 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-84 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-85 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-84 49
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-84 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-84 49
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-85 47
escN AAL57542.1 EscN Virulence LEE Protein 4e-81 46
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-81 46
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-81 46
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-81 46
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-81 46
escN AAC38383.1 EscN Virulence LEE Protein 1e-82 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 9e-83 46
escN AAC31513.1 L0034 Virulence LEE Protein 7e-83 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 9e-83 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 7e-83 46
escN AAK26715.1 EscN Virulence LEE Protein 4e-81 46
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-76 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-76 45
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 7e-77 45
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-70 45
escN YP_003236088.1 translocator EscN Virulence LEE Protein 4e-82 45
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-79 45
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-77 45
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-77 45
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-75 44
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-75 44
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-75 44
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-73 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-83 43
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 7e-75 42
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-70 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 8e-70 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-70 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-70 42
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 3e-71 42
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 9e-72 42
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 9e-72 42
invC AAS66861.1 InvC Not tested SSR-2 Protein 9e-64 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tresu_1125 YP_004365334.1 FliI/YscN family ATPase VFG2144 Protein 3e-99 52
Tresu_1125 YP_004365334.1 FliI/YscN family ATPase VFG0390 Protein 4e-98 51
Tresu_1125 YP_004365334.1 FliI/YscN family ATPase VFG0192 Protein 6e-103 50
Tresu_1125 YP_004365334.1 FliI/YscN family ATPase VFG0515 Protein 1e-84 49
Tresu_1125 YP_004365334.1 FliI/YscN family ATPase VFG1254 Protein 2e-88 49
Tresu_1125 YP_004365334.1 FliI/YscN family ATPase VFG0048 Protein 2e-95 48
Tresu_1125 YP_004365334.1 FliI/YscN family ATPase VFG2499 Protein 5e-80 47
Tresu_1125 YP_004365334.1 FliI/YscN family ATPase VFG0730 Protein 7e-83 46
Tresu_1125 YP_004365334.1 FliI/YscN family ATPase VFG0812 Protein 4e-83 46
Tresu_1125 YP_004365334.1 FliI/YscN family ATPase VFG2331 Protein 1e-75 45
Tresu_1125 YP_004365334.1 FliI/YscN family ATPase VFG1778 Protein 6e-70 44
Tresu_1125 YP_004365334.1 FliI/YscN family ATPase VFG2459 Protein 1e-75 43
Tresu_1125 YP_004365334.1 FliI/YscN family ATPase VFG0555 Protein 3e-70 42
Tresu_1125 YP_004365334.1 FliI/YscN family ATPase VFG1008 Protein 1e-65 42