Gene Information

Name : Hipma_1198 (Hipma_1198)
Accession : YP_004340219.1
Strain : Hippea maritima DSM 10411
Genome accession: NC_015318
Putative virulence/resistance : Virulence
Product : FliI/YscN family ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 1190687 - 1191991 bp
Length : 1305 bp
Strand : -
Note : COGs: COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; InterPro IPR003593; IPR005714; IPR004100; IPR000194; KEGG: cth:Cthe_0468 flagellar protein export ATPase FliI; PFAM: ATPase, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/

DNA sequence :
ATGAGTGATATATTAAAGCTAAAAAGGGTTATAGATGGTTCAAATTTGATAGTTACATATGGAAGAATAAAGAAGGTTGC
GGGTATTACAATAAAATCTACAGGTCCTAAAAATGTAAAGATAGGTGATGTTTGCAAAATAGAAACAGATGAGGGGTGGA
TAGACTCAGAGGTTGTAGGTTTTGATGAAGATGGGGTTGTATTGATGCCTTTAGGTGTTTTGGATGGTGTTAAGTCGCTG
AGCTTGGTTAAATCTGAAGGTAGGGGTTTAAGTGTTCCGGTTAGTGAGAGACTCCTTGGAAGGGTTGTAAATGCCCTTGG
TAGACCTATTGATGGGAAAGGTCCTATACCTGTTGAAGAATACTATCCTGTCTATCCAAAGCCTGTTCCACCATTGGAAA
GGCAAATAATAAAAGAGCCTCTGTCTTTGGGTGTTAAAGCCATTGATGGGCTGTTAACCATAGGTAAGGGGCAGCGTGTA
GGCATATTTGCGGGTAGTGGGGTAGGTAAAAGTACTCTCCTTGGAATGATAGCAAGAAATAGTTCGGCAGATGTCAATGT
TATAGCCCTAATAGGTGAGCGTGGAAGAGAAGTTAGGGAATTTATAGAGAGAGATTTAAAAGAAGAGGGTTTAAAAAGAA
GCGTTGTTGTAGTTGCAACCAGTGATGAAGCTTCCCTTTTGAGAAGGGAAGGGGCTTTTGTTGCCACCTCTATTGCTGAA
TTTTTTAAAGATAGAGGGGCAAATGTTATGTTGATGATGGATTCTGCCACGAGGTTTGCTATGGCGCAGAGGGAGATTGG
TTTGGCTGTTGGAGAACCACCAACTACAAAAGGCTACACGCCCAGTGTTTTTACACTCCTACCACGTCTGATGGAAAGAG
CAGGCAATTTCAATAAGGGCTCTATCACTGCCATCTATACAGTATTGGTGGATGGGGATGATTTAATGGAACCTATAGCC
GATGCATCGCGTTCAATATTAGATGGCCATATAGTTTTATCCAGAAAGATAGCAGAGAGAGGAAGATATCCTGCTGTAGA
TGTTCTTAGGAGTATATCAAGGTTGATGAGTTCCATAACAACTGATGAGCATAAAGAATTGGCTTTGAAGATTAGAAAAG
TGCTTTCCGTATATGCAGATGCAGAGGATTTGATAAATATAGGTGCTTATGTGAAAGGAAGCAATAAGGATATAGATGAG
GCTATAAAATACATAGATAAAGTTGAAGGGTTTTTAGCTCAAAAGATAGAAGAGTCTTTTTCTTTTGAGGATACCTTAAA
TCTTATGAGAGGTATATTTAGTTAA

Protein sequence :
MSDILKLKRVIDGSNLIVTYGRIKKVAGITIKSTGPKNVKIGDVCKIETDEGWIDSEVVGFDEDGVVLMPLGVLDGVKSL
SLVKSEGRGLSVPVSERLLGRVVNALGRPIDGKGPIPVEEYYPVYPKPVPPLERQIIKEPLSLGVKAIDGLLTIGKGQRV
GIFAGSGVGKSTLLGMIARNSSADVNVIALIGERGREVREFIERDLKEEGLKRSVVVVATSDEASLLRREGAFVATSIAE
FFKDRGANVMLMMDSATRFAMAQREIGLAVGEPPTTKGYTPSVFTLLPRLMERAGNFNKGSITAIYTVLVDGDDLMEPIA
DASRSILDGHIVLSRKIAERGRYPAVDVLRSISRLMSSITTDEHKELALKIRKVLSVYADAEDLINIGAYVKGSNKDIDE
AIKYIDKVEGFLAQKIEESFSFEDTLNLMRGIFS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-96 52
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-92 51
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-93 51
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 3e-93 51
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-93 51
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 3e-93 51
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 8e-94 51
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-93 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-91 50
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-91 50
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-81 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 5e-82 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-82 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-82 49
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 5e-81 49
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-81 48
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-81 48
escN CAC81862.1 EscN protein Virulence LEE II Protein 5e-82 48
escN AAC38383.1 EscN Virulence LEE Protein 5e-81 48
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-81 48
escN CAI43874.1 EscN protein Virulence LEE Protein 5e-82 48
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 7e-82 48
escN AAC31513.1 L0034 Virulence LEE Protein 2e-81 48
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-81 48
escN YP_003223475.1 translocator EscN Virulence LEE Protein 6e-82 48
escN AAK26715.1 EscN Virulence LEE Protein 1e-81 48
escN YP_003236088.1 translocator EscN Virulence LEE Protein 4e-82 48
escN AAL57542.1 EscN Virulence LEE Protein 1e-81 48
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-80 48
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 6e-75 47
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 4e-77 47
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-77 47
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-77 47
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 6e-78 47
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-79 47
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 5e-73 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 3e-70 46
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 4e-74 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-74 46
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-77 44
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-77 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 9e-72 44
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 9e-72 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-66 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 6e-66 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-66 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-66 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 4e-67 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hipma_1198 YP_004340219.1 FliI/YscN family ATPase VFG0048 Protein 6e-96 54
Hipma_1198 YP_004340219.1 FliI/YscN family ATPase VFG2144 Protein 1e-98 53
Hipma_1198 YP_004340219.1 FliI/YscN family ATPase VFG0390 Protein 2e-101 53
Hipma_1198 YP_004340219.1 FliI/YscN family ATPase VFG0192 Protein 8e-100 52
Hipma_1198 YP_004340219.1 FliI/YscN family ATPase VFG0515 Protein 3e-82 49
Hipma_1198 YP_004340219.1 FliI/YscN family ATPase VFG1254 Protein 8e-86 49
Hipma_1198 YP_004340219.1 FliI/YscN family ATPase VFG2499 Protein 3e-87 49
Hipma_1198 YP_004340219.1 FliI/YscN family ATPase VFG0730 Protein 3e-81 48
Hipma_1198 YP_004340219.1 FliI/YscN family ATPase VFG0812 Protein 9e-82 48
Hipma_1198 YP_004340219.1 FliI/YscN family ATPase VFG2331 Protein 3e-82 47
Hipma_1198 YP_004340219.1 FliI/YscN family ATPase VFG0555 Protein 3e-66 42
Hipma_1198 YP_004340219.1 FliI/YscN family ATPase VFG1008 Protein 6e-69 42
Hipma_1198 YP_004340219.1 FliI/YscN family ATPase VFG2459 Protein 3e-73 42
Hipma_1198 YP_004340219.1 FliI/YscN family ATPase VFG1778 Protein 6e-68 41