Gene Information

Name : Psed_6722 (Psed_6722)
Accession : YP_004336672.1
Strain :
Genome accession: NC_015314
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.16.1.1
Position : 33851 - 35275 bp
Length : 1425 bp
Strand : +
Note : TIGRFAM: Mercury reductase, MerA; KEGG: mil:ML5_4212 mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation

DNA sequence : 
GTGCTCCAGGCACACACCGGTTACGACCTGGCGATCATCGGCTCGGGCGCCGGCGCGTTCGCCGCGGCCATCGCGGCCCG
CAACAAGGGCAGGAGCGTGGTGATGGTCGAGCGCGGCATCACCGGCGGCACCTGCGTGAACGTCGGCTGCGTGCCGTCCA
AGGCGCTGCTGGCCGCCGCCGAGGCCCGTCACGGCGCCCAGGCGGCGAGCCGGTTCCCCGGCATACAGGCCACCGAGCCC
GCGCTGGACTTCCCCGCGCTGATCGGCGGCAAGGACACGCTGGTGGGACAGCTGCGGGCGGAGAAGTACACCGACCTGGC
CGCCGAGTACGGCTGGCGGATCGTGCACGGCACCGCCACCTTCGCCGACGGCCCCGTCCTGCAGGTCGCGCTGAACGACG
GCGGCACCACCACCATCGAGGCCGCCCACTACCTGATCGCCACCGGCTCCGCCCCCACCGCGCCGCCCATCGACGGCCTG
GACCAGGTGGACCACCTGACCTCCACCACCGCCATGGAACTCCAGCAACTCCCCGAGCACCTGCTGGTCCTCGGCGGCGG
CTACGTCGGCCTGGAGCAGGCCCAGCTCTTCGCCCGCCTCGGCAGCCGGGTCACCCTGGCCGTCCGCTCCCGTCTGGCCT
CTTGGGAAGAGCCGGAGATCTCCGCCGGAATCGAGGACATCTTCCGCGAGGAGGGCATCACCGTCCACACCCGCACCCAG
CTCCGTGCGGTCCGCCGCGACGGCGACGGAATCCTCGCCACCCTCACCGGCCCCGACGGTGAGCAGCAGGTGCGCGCCAG
TCGCCTGCTGATCGCCACCGGACGACGGCCCGTCACCGACGGACTCGGCCTGGAGCGGGTCGGGGTGAAGACCGGCGAGA
GCGGCGAGGTCGTGGTGGACGAGTACTTGCGCACCGGCAACCCGCGCATCTGGGCGGCCGGAGACGTCACCGGCCACCCG
GACTTCGTGTACGTCGCCGCCGCGCACGGAACCCTGGTCGCCGACAACGCCCTGGACGGCGTCGAGCGCACCCTGGACTA
CACCGCGCTGCCGAAGGTCACCTTCACCAGCCCCGCCATCGCCTCGGTCGGGATGACCGAGGCCCAGCTGACCGAGGCCG
GTATCGCCCACCAGACCCGCACCCTGCCGCTGGAGAACGTCCCCCGAGCCTTGGTCAACCGGGACACCCGCGGGCTGGTC
AAGCTCATCGCCGAACGCGGCAGCGGGAAGCTGCTGGCCGCCCACGTCCTGGCCGACAGCGCCGGCGACATCATCACCGC
CGCCACCTACGCCATCACCGCCGGGATGACCGTCGACCAGCTCGCCCACACCTGGCACCCCTACCTGACCATGGCCGAAG
CGTTGAAGCTCGCCGCCCAGACCTTCACCTCCGACGTCGCCAAGCTCTCCTGCTGCGCCGGCTGA

Protein sequence : 
MLQAHTGYDLAIIGSGAGAFAAAIAARNKGRSVVMVERGITGGTCVNVGCVPSKALLAAAEARHGAQAASRFPGIQATEP
ALDFPALIGGKDTLVGQLRAEKYTDLAAEYGWRIVHGTATFADGPVLQVALNDGGTTTIEAAHYLIATGSAPTAPPIDGL
DQVDHLTSTTAMELQQLPEHLLVLGGGYVGLEQAQLFARLGSRVTLAVRSRLASWEEPEISAGIEDIFREEGITVHTRTQ
LRAVRRDGDGILATLTGPDGEQQVRASRLLIATGRRPVTDGLGLERVGVKTGESGEVVVDEYLRTGNPRIWAAGDVTGHP
DFVYVAAAHGTLVADNALDGVERTLDYTALPKVTFTSPAIASVGMTEAQLTEAGIAHQTRTLPLENVPRALVNRDTRGLV
KLIAERGSGKLLAAHVLADSAGDIITAATYAITAGMTVDQLAHTWHPYLTMAEALKLAAQTFTSDVAKLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 3e-90 49
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 3e-90 49
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 1e-74 48
merA ABQ57371.1 MerA Not tested SGI1 Protein 7e-76 47
merA AGK07021.1 MerA Not tested SGI1 Protein 7e-76 47
merA AGK07079.1 MerA Not tested SGI1 Protein 7e-76 47
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 2e-73 47
merA AFG30120.1 MerA Not tested PAGI-2 Protein 2e-73 47
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 3e-73 47
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 3e-73 46
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 4e-73 46
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 1e-72 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Psed_6722 YP_004336672.1 mercuric reductase BAC0651 Protein 2e-90 49
Psed_6722 YP_004336672.1 mercuric reductase BAC0653 Protein 2e-75 48
Psed_6722 YP_004336672.1 mercuric reductase BAC0224 Protein 3e-86 48
Psed_6722 YP_004336672.1 mercuric reductase BAC0652 Protein 8e-76 47
Psed_6722 YP_004336672.1 mercuric reductase BAC0650 Protein 2e-68 44