Gene Information

Name : Psed_6517 (Psed_6517)
Accession : YP_004336459.1
Strain : Pseudonocardia dioxanivorans CB1190
Genome accession: NC_015312
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 6897822 - 6899534 bp
Length : 1713 bp
Strand : +
Note : PFAM: Amidohydrolase 1; Urease alpha-subunit, N-terminal; TIGRFAM: Urease, alpha subunit; HAMAP: Urease, alpha subunit; KEGG: amd:AMED_8448 urease alpha subunit

DNA sequence :
ATGACGGCCATCGACCGGGCCCGCTATGCAGACCTGTTCGGCCCGACGACGGGCGACCGCATCCGGCTGGCCGACACGAA
CCTGCTGATCGAGGTGACCGAGGACCGCAGCCGTGGGCCGGCCTCGGGCGACGAGGTGATCTTCGGCGGCGGCAAGGTCA
TCCGCGAGTCCATGGGTCAGTCCACGGTGACCTCGGCCGAGGGCGCCCCCGACCTGGTCATCACCGGCGCGGTGGTCCTG
GACCACTGGGGCGTCGTCAAGGCGGACGTCGGCATCACCGACGGGCGCATCACCGGGATCGGCAAGGCGGGCAACCCGGA
CACCATGGACGGCGTGGACTTCCCCATCGGGCCGTCCACGGAGATCATCGCCGGGAACGGCAAGATCCTCACCGCGGGTG
GGATCGACGTCCACGTCCACTTCATCACTCCGGGGCTCGTCGACACCGCGCTCGCCGCGGGGCTCACGACGCTGGGCGGC
GGCGGCACCGGGCCCGCCGAGGGCACGAAGGCCACGACCGTCACGCCCGGGCCGCGCAACCTCGCGCGGATGTTCCAGGC
GCTCGACCACCTGCCGGTCAACGTCCTGCTGATGGGCAAGGGCAACACGACCAGCACCGACGCGCTCTGGGAGCAGCTGC
GGGCGGGCGCGGGCGGGTTCAAGCTGCACGAGGACTGGGGGACGACCCCGGCGGCGATCGACGCGTGCCTGCGCGTCGCG
GACGCGTCCGGCGTACAGGTCGCCATCCACACCGACACCCTCAACGAGGCCGGTTTCCTGGAGTCGACGGTCGAGGCGAT
CGCCGGCCGCTCGATCAACGCGTTCCACACCGAGGGCGCCGGCGGCGGGCACGCGCCGGACATCATCGAGGTCGTCGGGA
CGGGGAACATCCTGCCCAGCTCGACGAACCCGACCCGGCCGCACACCGTCAACACGCTCGACGAGCACCTCGACATGCTG
ATGGTCTGCCACCACCTCAACCCGTCGGTACCCGAGGACCTGGCGTTCGCCGAGAGCCGCATCAGGCCGACGACGATCGC
CGCCGAGGACGTGCTGCACGACATCGGCGCGATCTCGATGATGAGCTCGGACTCGCAGGCCATGGGCCGCATCGGCGAGG
TCGTCATCCGCACCTGGCAGACCGCGCACGTCATGAAGGCGGCCCGCGGCGCGCTGCCCGGCGACGGGCAGGCCGACAAC
CTGCGGGCGCGGCGCTACGTCGCGAAGTACACGATCAACCCGGCGATCGCGCACGGCATGGGCGAGGAGATCGGGTCGGT
CGAGGTCGGCAAGCTCGCCGACCTCGTGTTGTGGGACCCGAAGTTCTTCGGCATCCGCCCCGACCTCGTGCTCAAGGGCG
GGTTCATCGCGTGGGCCGCGATGGGCGACGCCAACGCGTCGATCCCGACCCCGCAGCCGGTGCTGGCCCGGCCGATGTTC
GGCGCGGCACCGGCGGTCGCGGCGGCGACGAGCCTGAACTTCGTCGCCCCCGCGGCGCTGGAGGCGCGGTCGCTGGAGTC
GCTCGGCCTCGCGAAGCCGGCCGCGCCGGTCGCGGACACCCGGTCGGTGACCAAGGCCCACATGCTGCTCAACGACGCGA
CCCCCTCGGTGAAGGTCGATCCCGACTCCTTCGAGGTGCGGATCGACGGCGACGTCGTCGAGCCCGCCCCGGTGTCCGAG
CTGCCGATGGCCCAGCGCTACTTCCTGTTCTGA

Protein sequence :
MTAIDRARYADLFGPTTGDRIRLADTNLLIEVTEDRSRGPASGDEVIFGGGKVIRESMGQSTVTSAEGAPDLVITGAVVL
DHWGVVKADVGITDGRITGIGKAGNPDTMDGVDFPIGPSTEIIAGNGKILTAGGIDVHVHFITPGLVDTALAAGLTTLGG
GGTGPAEGTKATTVTPGPRNLARMFQALDHLPVNVLLMGKGNTTSTDALWEQLRAGAGGFKLHEDWGTTPAAIDACLRVA
DASGVQVAIHTDTLNEAGFLESTVEAIAGRSINAFHTEGAGGGHAPDIIEVVGTGNILPSSTNPTRPHTVNTLDEHLDML
MVCHHLNPSVPEDLAFAESRIRPTTIAAEDVLHDIGAISMMSSDSQAMGRIGEVVIRTWQTAHVMKAARGALPGDGQADN
LRARRYVAKYTINPAIAHGMGEEIGSVEVGKLADLVLWDPKFFGIRPDLVLKGGFIAWAAMGDANASIPTPQPVLARPMF
GAAPAVAAATSLNFVAPAALEARSLESLGLAKPAAPVADTRSVTKAHMLLNDATPSVKVDPDSFEVRIDGDVVEPAPVSE
LPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-155 61
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-155 61
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-150 58
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-150 58
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-150 58
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-150 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Psed_6517 YP_004336459.1 urease subunit alpha VFG0270 Protein 5e-136 56