Gene Information

Name : Psed_5064 (Psed_5064)
Accession : YP_004335055.1
Strain : Pseudonocardia dioxanivorans CB1190
Genome accession: NC_015312
Putative virulence/resistance : Virulence
Product : (2,3-dihydroxybenzoyl)adenylate synthase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 5419277 - 5420962 bp
Length : 1686 bp
Strand : -
Note : KEGG: saq:Sare_4933 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase

DNA sequence :
ATGCCCGGCCCCGTCAGTGAGCACACCGTCCCCTGGCCTGCCACGGAGGTCGAGCGGTATGTCGCCGCGGGCTACTGGCA
GGGGGTCCCGCTCGGGCACCTGCTCCGTGGGGTCGCCGACCGCACGCCCGATGCGCCCGCGCTCGTCGACGCGGCGACGG
GGCTGCGGCTGACCCATCGCGAGCTCGCGGACCGGGCGGACGCCACCGCGGCCCGCCTCCTGGACCTGGGCCTCGCACGC
GGCGATCGGATTCTGGTACAGCTCGGGAACGGCGGAGAGTTCGTGATCCTCACCCTGGCCTGCCTCCGCGCCGGGGTCGT
ACCGGTGATGGCGCTGCCCGCGCACCGACGGACGGAGCTGAGCCACCTCGCCGCGCACGCCGAGGCCGTGGCGATCGCGG
TCCCCGACCGGATGCGGGACTTCGACCACCAGGCGCTCGCCCACGATCTGGGCCCGGGCGTGCAGGAGATCACGGGTGCG
GACTGGCTCGTGCTGGTCGACGGCGACCACGTCGACGACGCGAGTGTCGATCTGCGCGCGCTCTGCGGGCCCGGGACGGG
GGAGGAGCGCGCCCGGTTGGAGGCGGCCTGTCCCGAGAGCCGGGACGTGGCCGTGTTCCTGCTCTCCGGCGGGACCACCG
GTCTTCCCAAACTGATTGCCCGCACCCACGACGACTACGCCTACAACGCTCGGGCCAGCGCGGACATGGCTGGGGTCGAC
GCGGACTCGGTGTACCTGGTCAGCCTGCCGGCGGGGCACAACTTTCCGCTCGCCTGCCCGGGCATGCTCGGGGTACTGCT
CGCCGGTGGGACCGTCGTCATGCTGCCGTCGCCGGAGCCGACGCGGGCGTTCGCCACGATCGCGGCGGAGGGGGTCACGC
ACACCGCTGTCGTCCCGGCGGTTGCCGGCCGCTGGCTGGAGCACGCGGGCGAGCACGGTGCCCCGCCGTCGCTGCGGGTG
CTGCAGGTCGGTGGGGCACGCCTGGCCGACGAGCTCGCTCATCGCGTCGAGCCGGTGCTCGGGGCGCGACTGCAGCAGGT
GTTCGGGATGGCCGAGGGCCTCCTGAACTTCACCCGCCTGGACGACCCGATCGACGTCATCTGCACCACGCAGGGCCGTC
CGATGTGCCCGGACGACGAGGTGCGCCTCGTCGACGAGCTGGACGTCGACGTCGCCGAGGGCACGCCCGGCTCGCTGCTC
ACGCGCGGCCCCTACACGCCGCGCGGGTACTACCGCGCCCCCGAGCAGAACGCGCGGGCATTCACAGCGGACGGTTGGTT
CCGCTCCGGTGACATCTGCCGCCGTACGCCCGAGGGCAACCTGATCGTGGAGGGCAGGGACAAGGACATGATCAACCGTG
GTGGAGAGAAGATCTCCGCCGAGGAGATCGAGAACCTCGTCTACCAGATGCCCGCGGTGGGCCAGGTCGCCGCGGTCGCG
ATGCCGGACCGGGAGCTCGGCGAGCGCGTGTGCCTGTACGTCGTGCCCCGGCCGGGCGCGACGCTCACCCTCGACGAGGT
GCGCGCAGCCATGGCCGCGCTCGGGGTGGCGAAGTTCAAGTGGCCGGAGCGCTTGGAGATCGTCGATGCGCTGATGTCGA
CGAAGGTCGGCAAGATCGACAAGAAAGCGCTGCGGGCCGACGTCGCCGAGCGCCTCGCGCACGAGTCCACCGGAGCGACT
CCATGA

Protein sequence :
MPGPVSEHTVPWPATEVERYVAAGYWQGVPLGHLLRGVADRTPDAPALVDAATGLRLTHRELADRADATAARLLDLGLAR
GDRILVQLGNGGEFVILTLACLRAGVVPVMALPAHRRTELSHLAAHAEAVAIAVPDRMRDFDHQALAHDLGPGVQEITGA
DWLVLVDGDHVDDASVDLRALCGPGTGEERARLEAACPESRDVAVFLLSGGTTGLPKLIARTHDDYAYNARASADMAGVD
ADSVYLVSLPAGHNFPLACPGMLGVLLAGGTVVMLPSPEPTRAFATIAAEGVTHTAVVPAVAGRWLEHAGEHGAPPSLRV
LQVGGARLADELAHRVEPVLGARLQQVFGMAEGLLNFTRLDDPIDVICTTQGRPMCPDDEVRLVDELDVDVAEGTPGSLL
TRGPYTPRGYYRAPEQNARAFTADGWFRSGDICRRTPEGNLIVEGRDKDMINRGGEKISAEEIENLVYQMPAVGQVAAVA
MPDRELGERVCLYVVPRPGATLTLDEVRAAMAALGVAKFKWPERLEIVDALMSTKVGKIDKKALRADVAERLAHESTGAT
P

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-75 46
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-75 46
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-75 46
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-75 46
ybtE CAA21394.1 - Virulence HPI Protein 2e-75 46
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 8e-76 46
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-75 46
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-75 46
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 6e-76 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Psed_5064 YP_004335055.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG0168 Protein 1e-90 48
Psed_5064 YP_004335055.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG1817 Protein 4e-83 48
Psed_5064 YP_004335055.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG0932 Protein 4e-80 43