Gene Information

Name : Psed_1317 (Psed_1317)
Accession : YP_004331413.1
Strain : Pseudonocardia dioxanivorans CB1190
Genome accession: NC_015312
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.16.1.1
Position : 1377549 - 1378970 bp
Length : 1422 bp
Strand : +
Note : TIGRFAM: Mercury reductase, MerA; KEGG: mil:ML5_4212 mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation

DNA sequence : 
ATGCGGTACGACCTGGCGGTGATCGGTTCCGGTGGGGCTGGGTTCGCCGCGGCGATCGCGGCCCGGACCAAGGGCCGCAC
GGTGGTGATGATCGAGCGCGACACCGTCGGCGGGACGTGCGTGAACACCGGGTGCGTGCCGTCGAAGGCACTGCTGGCCG
CCGCCGAGGCCCGCCACGTCAGCCTGGACGGCCGGTTCCCCGGCATCAGTGTCACCCCGTTCGGCGTGGACCTGCCGCGC
CTGATCGACAGCAAACGGGACCTGGTGGACTCGTTGCGGGCGGAGAAGTACACCGACCTGGCCGCCGAGTACGGCTGGGA
CAGCCTCCACGGCACCGCCACCTTCACCACCGACGGGCCGGATCCGGCGCTGCACGTGGACCTCGCCGACGGCGGCACGG
CCACGGTGGTGGCCGAGCACTATCTGGTCGCCACTGGCTCGGCCCCGTGGGCACCCCCGATCGACGGCCTCGCCGAGGCC
GGGTACCTAACCTCGACCACCGCGATGGAACTCGACACGCTGCCCGCCTCGATGACCGTGATCGGCGGCAACGCGATCGG
CCTGGAACAAGCCCAGCTGTGGAACCGCCTAGGCGTCCACGTCACGGTGGTGGAAGCACTGGACCGGCTGGCGCCGTTCG
AGGAACCCGACGTCTCCGCTGCGATCGACGAGGTGTTCACCCGTGAGGGCATCCGGGTGGTCATCGGCGCCACCATCACC
CGCGCCGACTGCGACGGCGGCGGCTACCGGGTGGAAGTCACCGGCGCCGACGGTCAGCTCACCGAACTCCTCGCCGAGCA
ACTGCTCGTGGCGACCGGCCGCCGTCCGGTCACCGCCGGGTTGAACCTGGCCGAGGTCGGGGTGAAAACCGGTCCGCGCG
GCGAGGTGATCGTCGATGACTCCCTGCGCACCGACAACCCGCGGATCTGGGCGGCTGGGGACGTCACCGGGCACCCGCAG
TTCGTCTACGTCGCCGGAGCCCACGGCACCCTCGTCGCCGACAACGCGTTCGACAACGCCCGGCGCACGCTGGATTACCA
CCACCTGCCGCGCGTGACCTTCACCAGCCCCGCGATCGCCTCGGCCGGGCTGACCGACGCCCAGGCCGTCGAGCAAGGTT
TTGCGTGCGAGTGCCGCGTGCTGCCCTTGGAGTACGTGCCGCGGGCGCTGGTCAACCGCGACACCCACGGACTGATCAAA
CTCGTCGCAGACCGGAACACCGGCCGCCTGCTCGGCGCGCACGTGGTCGCCGAGGGTGCCGGGGACGTGATCGCCACCGC
CGTCTACGCGCTGGCGAACGACATGACGGTGCGGCAGATGGCCGACCTGTGGTGCCCGTACCTGACCATGGCTGAAGGCA
TCAAACTTGCCGCCCAGACCTTCACCCGCGACGTGTCCAAGCTGTCCTGCTGCGCCTCCTGA

Protein sequence : 
MRYDLAVIGSGGAGFAAAIAARTKGRTVVMIERDTVGGTCVNTGCVPSKALLAAAEARHVSLDGRFPGISVTPFGVDLPR
LIDSKRDLVDSLRAEKYTDLAAEYGWDSLHGTATFTTDGPDPALHVDLADGGTATVVAEHYLVATGSAPWAPPIDGLAEA
GYLTSTTAMELDTLPASMTVIGGNAIGLEQAQLWNRLGVHVTVVEALDRLAPFEEPDVSAAIDEVFTREGIRVVIGATIT
RADCDGGGYRVEVTGADGQLTELLAEQLLVATGRRPVTAGLNLAEVGVKTGPRGEVIVDDSLRTDNPRIWAAGDVTGHPQ
FVYVAGAHGTLVADNAFDNARRTLDYHHLPRVTFTSPAIASAGLTDAQAVEQGFACECRVLPLEYVPRALVNRDTHGLIK
LVADRNTGRLLGAHVVAEGAGDVIATAVYALANDMTVRQMADLWCPYLTMAEGIKLAAQTFTRDVSKLSCCAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 2e-94 48
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 1e-94 48
merA ABQ57371.1 MerA Not tested SGI1 Protein 1e-75 44
merA AGK07021.1 MerA Not tested SGI1 Protein 1e-75 44
merA AGK07079.1 MerA Not tested SGI1 Protein 1e-75 44
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 4e-76 44
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 4e-76 44
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 2e-72 43
merA AFG30120.1 MerA Not tested PAGI-2 Protein 2e-72 43
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 3e-72 43
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 8e-74 43
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 1e-72 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Psed_1317 YP_004331413.1 mercuric reductase BAC0651 Protein 9e-95 48
Psed_1317 YP_004331413.1 mercuric reductase BAC0224 Protein 4e-96 48
Psed_1317 YP_004331413.1 mercuric reductase BAC0652 Protein 1e-76 44
Psed_1317 YP_004331413.1 mercuric reductase BAC0653 Protein 1e-76 43
Psed_1317 YP_004331413.1 mercuric reductase BAC0650 Protein 3e-69 42