Gene Information

Name : kdsB (HMPREF9137_2340)
Accession : YP_004329984.1
Strain : Prevotella denticola F0289
Genome accession: NC_015311
Putative virulence/resistance : Virulence
Product : 3-deoxy-D-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2739883 - 2740800 bp
Length : 918 bp
Strand : -
Note : identified by match to protein family HMM PF02348; match to protein family HMM TIGR00466

DNA sequence :
TTGTGTTGCAAGATTGCCTGCACCTATCAACGACACCTTCATCATACCGACAAATTTAATACTTTTAAAGGAAATAAGTC
TGAAATACACTTCCATTTTAAAAAAGATTTGCTATTTTTGTGCGTACTTCTGCCAAGGAAGTGTGACATATCAAACTTTA
AAAGGATAAAGGAATCTATGGAATTTATCGGAATTATCCCGGCTCGCTACGGCTCTTCACGTTTTCCTGGAAAGCCTCTT
GCAATGCTTGGAGGAAAGACCGTCATCGAGCACGTTTACAGGCAAGTAAGCAGCGTGTTGACAGATGTCTATGTGGCCAC
AGACGATCCCCGTATTCATAACGCTGTTGCAGCGTTCGGCGGAAAGTCCGTAATGACCCGTCCCGACCATAAAAGCGGCA
CGGACAGAATCTGCGAAGCACTCGATAAAATCGGTGGCAGCTTCGATGTCGTCATCAACATCCAGGGCGATGAACCTTTC
ATACAGAAAAGCCAGATTGAGACAGTCATGCAGTGTTTTGATGATTCACGCACACAGATTGCCACGCTGGGCAAGCCTTT
TGAGACCATTGAGGCTGCACAGAATCCCAATTCGCCCAAGATAGTCCTCGACAACAATGGCTATGCCCTTTATTTCTCAC
GCTCCGTCATACCCTTTGTTCGGGGCAAGGCGACTTCGGAATGGCTTTCCACCTATCCTTTCCTCAAGCACATCGGGCTA
TATGCCTACCGCACAGAAGTGCTGCGTGAGGTGAGCCGTCTTCCGCAATCCTCGCTCGAACTGGCCGAAAGTCTCGAACA
GCTGCGATGGCTGCAGAACGGTTATAAAATCAAGGTAGGTCTGACAGATGTAGAGACAATCGGCATTGATACGCCGGAAG
ACCTGCAACGGGCAGAGCGGCAATTGTCTGCCCTGTAA

Protein sequence :
MCCKIACTYQRHLHHTDKFNTFKGNKSEIHFHFKKDLLFLCVLLPRKCDISNFKRIKESMEFIGIIPARYGSSRFPGKPL
AMLGGKTVIEHVYRQVSSVLTDVYVATDDPRIHNAVAAFGGKSVMTRPDHKSGTDRICEALDKIGGSFDVVINIQGDEPF
IQKSQIETVMQCFDDSRTQIATLGKPFETIEAAQNPNSPKIVLDNNGYALYFSRSVIPFVRGKATSEWLSTYPFLKHIGL
YAYRTEVLREVSRLPQSSLELAESLEQLRWLQNGYKIKVGLTDVETIGIDTPEDLQRAERQLSAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-39 48
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 6e-39 47
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 9e-39 47