Gene Information

Name : clpC (SOR_1933)
Accession : YP_004326920.1
Strain : Streptococcus oralis Uo5
Genome accession: NC_015291
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1896506 - 1898938 bp
Length : 2433 bp
Strand : -
Note : -

DNA sequence :
ATGAATTATTCAAAAGCATTGAATGAATGTATCGAAAGTGCCTACATGGTTGCGGGCCATTTTGGAGCCCGATATCTAGA
GTCTTGGCATTTATTGATTGCCATGTCCAATCACAGTTACAGTGTGGCAGGTGCGACTCTAAATGATTATCCTTATGAAA
TGGATCGTTTAGAAGAGGTTGCTTTGGAACTGACTGAAACGGACTATAGCCAAGACGAAACCTTTACGGAATTGCCCTTT
TCCCATCGTTTGGAGGTTCTCTTTGCAGAAGCAGAGTATGTGGCCTCCGTGGTCCATGCAAAGGTGCTAGGTACAGAGCA
TGTCCTCTATGCGATTTTGCATGATGGCAATGCCTTGGCAACTCGCATCTTGGAGAGAGCAGGCTTTTCTTATGAAGACC
AGAAAGATCAGGTCAGAATTGCTGCTCTTCGTCGCAATTTAGAGGAACGTGCAGGTTGGACAAGAGAAGACCTTAAGGCT
TTGCGTCAACGCCATCGCACGGTAGCAGACAAGCAAAATTCCATGGCCAATATGATGGGCATGCCTCAGAATCCAAGTGG
TGGTCTAGAGGACTACACGCATGACCTGACGGAGCAAGCGCTCTCTGGCAAGTTAGAGCCAGTTATCGGTCGTGACAATG
AAATCTCACGTATGATTCAGATTTTGAGTCGGAAGACCAAGAACAATCCTGTCTTGGTTGGAGATGCTGGTGTCGGGAAA
ACAGCTCTGGCCCTTGGCCTTGCCCAGCGTATTGCTAGTGGGAATGTACCTGCGGAAATGGCCAAGATGCGCGTTTTGGA
ACTTGATTTGATGAATGTTGTTGCGGGGACACGTTTCCGTGGAGATTTTGAAGAGCGTATGAACAATATCATCAAGGATA
TCGAGGAAGATGGCAAAGTGATCCTCTTTATCGATGAACTCCACACCATCATGGGTTCTGGTAGTGGTATTGACTCGACG
CTGGATGCAGCCAATATCTTGAAGCCAGCTTTGGCACGTGGAACTTTGAGAACGGTTGGTGCAACCACTCAGGAAGAATA
CCAAAAACACATCGAAAAAGATGCAGCCCTTTCTCGACGTTTTGCAAAAGTGACGATTGAAGAGCCAAGTCTAGCTGACA
GTATGACTATTTTGCAAGGTTTGAAGTCTACCTATGAGAAACACCATCGTGTGCAAATCACAGATGAAGCTGTCGAAACG
GCTGTTAAGATGGCCCATCGTTACCTGACCAGTCGTCACTTGCCAGACTCTGCTATCGACCTCTTGGATGAAGCGGCAGC
AACTGTGCAAAACAAATCCAAGCATGTGAAAGCAGACGAATCCGACTTGAGTCCAGCTGACAAGGCCTTGATGGATGGCA
AGTGGAAACAAGCAGGCCAGCTAATCGCAAAGGAACAGGAAGTCCCTGTCTATAAAGACTTGGTAACAGAGACTGAAATC
CTGACTACTTTGAGCCGCTTGTCAGGGATTCCAGTTCAAAAACTGACTCAGACTGATGCTAAGAAATATCTGAACTTGGA
AGCTGAACTACACAAACGTGTCATCGGTCAAGATCAAGCTGTTTCAAGCATTAGCCGTGCGATTCGCCGCAACCAGTCAG
GGATTCGCAGTCACAAGCGTCCGATTGGTTCCTTTATGTTCCTAGGACCGACGGGTGTCGGTAAGACCGAATTGGCCAAG
GCTCTGGCAGAAGTTCTCTTTGATGACGAATCAGCCCTTATCCGCTTTGACATGAGTGAGTATATGGAGAAATTCGCAGC
CAACCGTCTCAATGGAGCTCCTCCGGGCTATGTGGGCTACGAAGAAGGTGGGGAGTTGACCGAGAAGGTTCGCAACAAAC
CATATTCCGTTCTCCTCTTTGACGAGGTAGAGAAGGCCCACCCAGATATCTTCAATGTTCTCTTGCAAGTCTTGGATGAT
GGAGTTCTAACAGACAGCAAGGGGCGTAAGGTTGACTTTTCAAATACCATCATCATTATGACGTCAAACCTTGGTGCGAC
GGCTCTTCGTGATGACAAGACAGTCGGCTTTGGGGCCAAGGACATTCGTTTTGACCAGGAAAATATGGAAAAACGAATCT
TCGAAGAGTTGAAAAAAGCTTATCGACCAGAGTTTATCAACCGTATTGATGAAAAGGTGGTCTTCCATAGCTTAGATAGC
AAACACATGCAGGAAATTGTCAAGATCATGGTGAAACCATTGATTGCTAGCCTGGTAGAGAAGGGCATCGACTTGAAACT
GCAAGCTTCAGCCCTGAAGTTGCTAGCTAGTCAAGGATATGATCCAGAAATGGGAGCCCGTCCACTTCGCAGAACCCTGC
AAACAGAAGTGGAAGACAAGCTAGCAGAACTCCTTCTTAAGGGAGAACTGGTAGCAGGCAAAACCCTCAAAATTGGTGTC
AAAGCTGGACAATTGAAATTTGATATTGCTTAA

Protein sequence :
MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETDYSQDETFTELPF
SHRLEVLFAEAEYVASVVHAKVLGTEHVLYAILHDGNALATRILERAGFSYEDQKDQVRIAALRRNLEERAGWTREDLKA
LRQRHRTVADKQNSMANMMGMPQNPSGGLEDYTHDLTEQALSGKLEPVIGRDNEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGNVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGKVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSLADSMTILQGLKSTYEKHHRVQITDEAVET
AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADESDLSPADKALMDGKWKQAGQLIAKEQEVPVYKDLVTETEI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAANRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQENMEKRIFEELKKAYRPEFINRIDEKVVFHSLDS
KHMQEIVKIMVKPLIASLVEKGIDLKLQASALKLLASQGYDPEMGARPLRRTLQTEVEDKLAELLLKGELVAGKTLKIGV
KAGQLKFDIA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 9e-139 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_004326920.1 ATP-dependent Clp protease, ATP-binding subunit VFG0079 Protein 1e-159 47
clpC YP_004326920.1 ATP-dependent Clp protease, ATP-binding subunit VFG0080 Protein 7e-123 43