Gene Information

Name : capD (SOR_1861)
Accession : YP_004326848.1
Strain : Streptococcus oralis Uo5
Genome accession: NC_015291
Putative virulence/resistance : Virulence
Product : putative nucleoside-diphosphate sugar isomerase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : -
Position : 1820340 - 1822190 bp
Length : 1851 bp
Strand : -
Note : required for the biosynthesis of pneumococcal type 1 capsular polysaccharide

DNA sequence :
ATGAATAAAAAACTAACAGATTATGTGATTGATCTGGTTGAAATTTTAAATAAACAGCAAAAACAAGTGTTTTGGGGGAT
ATTTGATATTCTGAGTATGGTGGTTTCCATCATCGTATCTTATATCTTGTTTTATGGCCTTATAAATCCGGCGCCTGTGG
ATTACGTCATCTACACTCTTTTAGCCTTCCTCCTCTATCAAATCATGATTGCGTTTTGGGGGCTAAATGCTAGTATTAGT
CGTTATAGCAAGATTACGGATTTCATGAAAATCTTTTTCGGAGTGATGCTCAGCAGTGTTCTTTCTTATGGAATCTGCTA
TGCCTTTCTTCCATTGTTTTCTATCCGTTTCATCGTACTCTTCATTTTGTTGAGTACCTTCCTCATCTTGCTTCCTCGTA
TCACTTGGCAGCTGATTTATTCTAAGCGTAAGCAAGGTAGTGGAGATGGAGAGCATCGTCGTACCTTCTTGATCGGTGCT
GGTGATGGTGGTGCCCTCTTTATGAACAGCTACCAACATCCAACTAGCGACCTTGAGCTAGTGGGGATATTGGATAATGA
TGAAAAGAAAAAGGGACAAAAACTAGGTGGAATCCCAGTTCTGGGCTCTTATGATAATCTACCTGAATTAGCTAAACGTC
ACCAAATCGAGCGTGTCATCGTAGCGATCCCTTCGCTTGACCCATCAGAGTACGAACGCATCTTGCAGATGTGTAATAAG
CTAGGCGTCAAATGTTACAAGATGCCTAAGGTTGAGACAGTCGTTCAAGGACTCCATCAACCAGGTAGTGGTTTCCAAAA
AATTGATATCACAGACCTTTTGGGCCGTCAGGAAATTCGTCTCGACGAATCGCGTCTGGGTACTGAGATTACAGGCAAGA
CCATCCTGGTGACAGGGGCAGGTGGTTCGATTGGTTCGGAGATTTGTCGTCAGGTTAGTCGCTTCAATCCCGAGCGTATC
GTCTTGCTTGGACATGGTGAAAACTCAATCTATCTCGTTTATCATGAATTGATCCGTACATTCCAAGGGATTGATTATGT
TCCTGTTATTGCAGATATTCAGGACTATGACCGTCTCTTGCAGGTGTTTGAGCAGTACAAACCAGCCATTGTTTACCATG
CTGCAGCCCACAAGCACGTTCCGATGATGGAGCGCAATCCAAAAGAAGCCTTCAAGAACAATATCCTCGGTACCTACAAT
GTTGCCAAGGCTGTTGATGAAGCCAAAGTACCTAAGATGGTCATGATTTCGACTGACAAGGCGGTCAATCCACCGAATGT
TATGGGCGCAACCAAGCGCGTGGCAGAGTTGATTGTCACTGGCTTTAACCAACGTAGTAAATCAACCTACTGTGCAGTCC
GTTTTGGGAATGTTCTCGGTAGTCGTGGTAGTGTGATTCCTGTCTTTGAACGTCAGATTGCTGAAGGCGGTCCTGTAACG
GTGACAGACTTCCGTATGACACGTTACTTCATGACCATTCCAGAGGCTAGCCGTCTAGTAATCCATGCTGGCGCTTATGC
CAAGGACGGAGAAGTCTTTATCCTCGATATGGGCAAACCAGTTAAGATCTATGACTTGGCTAAGAAAATGGTTCTTCTAA
GTGGGCACACGGAAAGTGAAATTCCAATCGTTGAGGTCGGTATCCGCCCGGGTGAAAAACTCTATGAAGAACTCTTGGTT
TCGACCGAATTGGTTGATAACCAAGTCATGGACAAGATTTTCGTTGGTAAGGTAAACGTCATGCCGCTAGAAGCCATCGA
TCAAAAGATTGAAGAATTCCGTTCACTCAGTGGAGATGAGCTCAAAGAAGCGATTATTTCCTTTGCAAATGAGACAACCC
ATGCTGAGTAA

Protein sequence :
MNKKLTDYVIDLVEILNKQQKQVFWGIFDILSMVVSIIVSYILFYGLINPAPVDYVIYTLLAFLLYQIMIAFWGLNASIS
RYSKITDFMKIFFGVMLSSVLSYGICYAFLPLFSIRFIVLFILLSTFLILLPRITWQLIYSKRKQGSGDGEHRRTFLIGA
GDGGALFMNSYQHPTSDLELVGILDNDEKKKGQKLGGIPVLGSYDNLPELAKRHQIERVIVAIPSLDPSEYERILQMCNK
LGVKCYKMPKVETVVQGLHQPGSGFQKIDITDLLGRQEIRLDESRLGTEITGKTILVTGAGGSIGSEICRQVSRFNPERI
VLLGHGENSIYLVYHELIRTFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFKNNILGTYN
VAKAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSKSTYCAVRFGNVLGSRGSVIPVFERQIAEGGPVT
VTDFRMTRYFMTIPEASRLVIHAGAYAKDGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLV
STELVDNQVMDKIFVGKVNVMPLEAIDQKIEEFRSLSGDELKEAIISFANETTHAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-102 54
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 3e-104 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
capD YP_004326848.1 putative nucleoside-diphosphate sugar isomerase VFG1300 Protein 2e-99 51