Gene Information

Name : leuS (HMPREF9243_0665)
Accession : YP_004320986.1
Strain : Aerococcus urinae ACS-120-V-Col10a
Genome accession: NC_015278
Putative virulence/resistance : Unknown
Product : leucine--tRNA ligase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 669108 - 671522 bp
Length : 2415 bp
Strand : +
Note : identified by match to protein family HMM PF00133; match to protein family HMM PF08264; match to protein family HMM PF09334; match to protein family HMM TIGR00396

DNA sequence :
ATGGCTTATAACCACAAGACGATAGAGAAAAAATGGCAAAAATATTGGAAAGACAATAAGAGCTTTAAAACCTTAGAGGA
CAAGTCCTTGCCTAAGTTTTATGCATTGGATATGTTCCCCTATCCTTCTGGTCAAGGGCTCCATGTGGGGCACCCAGAAG
GTTATACAGCAACCGATATTGTTTCGAGAATGAAGCGGGCCCAAGGTTATAATGTTCTCCATCCTATGGGTTGGGACGCG
TTTGGTTTGCCAGCGGAACAATATGCCCTCGATACCGGTAATGACCCCGCCGAATTTACCCAAGCCAATATCGAGGTCTT
CAAGAAACAAATTGAATCCCTCGGTTTTTCCTATGACTGGGACCGTGAAATTGACACCACTGATCCAGAATATTATAAGT
GGACCCAATGGATCTTCACCAAACTCTTTGAAAAGGGTCTAGCCTATGAAGATGAAATCATGGTTAACTGGTGTGAAGCC
TTGGGGACGGTTCTGGCTAATGAAGAAGTGATTGACGGCTTGTCTGAACGGGGCAATCATCCTGTGGTTCGGCGTCCGAT
GAAGCAATGGGTATTGAAGATTACCGCCTATGCTGATCGGCTTTTAGATGGTTTAGATGACTTGGATTGGCCAGAAAGCA
TTAAGGAAATGCAACGGAACTGGATTGGTCGTTCTGAAGGGGCCGATGTGACCTTTAAGGTGGCTGATACTGACAAAGAG
TTTGAAGTCTTTACCACTCGTCCTGATACCCTTTACGGAGCTACCTACTGTGCCTTAGCCCCAGAACACCCACTGATCAA
ACAAATTGTCAGCGAAGATCAAAAGCAAGCGGTGGCTGACTATGTTGAAGCTGCCAGCCATAAGTCTGACTTAGAACGTA
CCGATCTCGCTAAGGAGAAGACTGGGGTATTTACTGGGGCTTATGCGGTTAACCCACTCAACGGGGACAAGCTCCCTATC
TGGGTGGCTGACTATGTCTTGGTTTCTTATGGGAGCGGTGCCGTTATGGCTGTTCCTGCCCATGACCAAAGGGACTACGA
ATTTGCTAAGCAATTTGACCTTCCAATTAAAGCCGTTATCGAAGGCGGCGACCTGGAAAAAGAAGCCTACACTGGCGATG
AGGTCCACATTCATTCAGAAGAATTGGATGGCCTGGTTAAGGATGAAGCCATTGAAAAGGCTATTGAACTCTTAGAGGCT
AAGGGAGCTGGCCAAGCCAAGACCTCCTACCGTCTCCGCGACTGGGTTTTCTCTCGCCAACGCTACTGGGGGGAACCTAT
TCCTGTCATCCATTGGGAAGATGGGACCACTACAGCCGTTCCTGAAGCAGACTTACCAGTGCTCTTACCTGAGGGCAAAG
ATATTAAACCTTCTGGTACCGGAGAATCTCCTCTGGCTAACTTTGATGATTGGCTCAATGTCTATGATGAAGAAACAGGT
CTCCACGGTAAACGTGAAACCAATACTATGCCACAATGGGCAGGATCCAGCTGGTACTATATTCGCTTCTGTGATCCTAA
GAATAATGAAGAACTCATTAGCCAAGAAGCCGCTAACTATTGGATGAATGTTGACTTATATATCGGTGGGGCAGAACACG
CCGTGCTTCACCTCCTCTACGCCCGTTTTTGGAATATGTTCCTCTATGATTTAGGTGTTGTTCCCACAGAAGAGCCTTTC
CAAAAACTCTTTAACCAAGGAATGATTCTTGGCGAAGGTCACGAAAAGATGTCTAAATCAAAGGGCAATGTGGTCAACCC
TGATGACATTGTTGAACGTTACGGGGCAGACACCTTACGTTTGTATGAGATGTTTATGGGACCTCTGGATGCCTCAATTG
CCTGGAGTGAAGATGGCTTAGCGGGGGCTAGACGCTTCCTAGAAAGAGTCTGGCGTCTATTTGTGGATAGCGAAGACCAA
TTACGGGACCGCATCACTACTATCGATACCGGTGAATTAGATAAAGTCTATAACCAAACTGTCAAGAAAGTCACTGAAGA
CCTGGAAAAATTACACTTTAATACAGCTATTTCGCAAATGATGGTCTTTGTTAATGAAGCGAATAAGGCTGAAAGTATTC
CTTACGATTATGCCAAGGGCTTTGTCCAATTACTGGCTCCAATTGCTCCTCACTTGGGAGAAGAATTGTGGCAACGTCTA
ACTGGTGAAGCTGGAATTTCATATGTGCCATGGCCAAGTTACGACGAAAGCCAATTGGTCGAAGAAAGTATCGAAATTGT
TGTTCAAGTGAACGGTAAGATCAAGGAACGTCTCCAAGTGGCTAGTGGCCTTAGCCAAGAGGAATTGAGTCAAGCAGCCA
AAGACTCTGACAAGGTCCAAGCTGCCATTGCTGGTAAGGACGTTGTGAAGGTGATTGCTGTTCCAGATAAATTGGTTAAT
ATTGTGGTCAAATAG

Protein sequence :
MAYNHKTIEKKWQKYWKDNKSFKTLEDKSLPKFYALDMFPYPSGQGLHVGHPEGYTATDIVSRMKRAQGYNVLHPMGWDA
FGLPAEQYALDTGNDPAEFTQANIEVFKKQIESLGFSYDWDREIDTTDPEYYKWTQWIFTKLFEKGLAYEDEIMVNWCEA
LGTVLANEEVIDGLSERGNHPVVRRPMKQWVLKITAYADRLLDGLDDLDWPESIKEMQRNWIGRSEGADVTFKVADTDKE
FEVFTTRPDTLYGATYCALAPEHPLIKQIVSEDQKQAVADYVEAASHKSDLERTDLAKEKTGVFTGAYAVNPLNGDKLPI
WVADYVLVSYGSGAVMAVPAHDQRDYEFAKQFDLPIKAVIEGGDLEKEAYTGDEVHIHSEELDGLVKDEAIEKAIELLEA
KGAGQAKTSYRLRDWVFSRQRYWGEPIPVIHWEDGTTTAVPEADLPVLLPEGKDIKPSGTGESPLANFDDWLNVYDEETG
LHGKRETNTMPQWAGSSWYYIRFCDPKNNEELISQEAANYWMNVDLYIGGAEHAVLHLLYARFWNMFLYDLGVVPTEEPF
QKLFNQGMILGEGHEKMSKSKGNVVNPDDIVERYGADTLRLYEMFMGPLDASIAWSEDGLAGARRFLERVWRLFVDSEDQ
LRDRITTIDTGELDKVYNQTVKKVTEDLEKLHFNTAISQMMVFVNEANKAESIPYDYAKGFVQLLAPIAPHLGEELWQRL
TGEAGISYVPWPSYDESQLVEESIEIVVQVNGKIKERLQVASGLSQEELSQAAKDSDKVQAAIAGKDVVKVIAVPDKLVN
IVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 68