Gene Information

Name : lysS (HMPREF9243_0501)
Accession : YP_004320843.1
Strain : Aerococcus urinae ACS-120-V-Col10a
Genome accession: NC_015278
Putative virulence/resistance : Virulence
Product : lysine--tRNA ligase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 502593 - 504095 bp
Length : 1503 bp
Strand : +
Note : identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499

DNA sequence :
ATGGCAAAGGAAAACCAACAGCATGAAGCGATGAATGACCAAATGCAAGTCCGTCGCGAAAAAGTAGATGAATTAATAGA
AAATGGCTACCAACCATTTGCGAAAGGCTTTAAGCGCGATGCCCTCGCTCAAGAAATCCATGACCAGTATGAAGCTTTTG
ACAAGGATGAACTGGCTGATAAGGCAGTCTTTGTTAATATTGCTGGCCGCCTCATGACAAAAAGAGGGAAGGGCCGGGCC
GGTTTTGGTCATATCCAGGATGGCTCTGGTCAAATTCAAATTTATGTTCGTAAAGACGAAATTGGCGACAAGGATTATGT
GGATATCTGGAAGAAGGCTGACCTCGGTGATATTATCGCTGTTTCAGGTTATGTGATGCGGACCAATACCGGTGAATTAT
CGGTTAAGGCAGAAGAATTAAAACATCTAACCAAGGCGCTGCGCCCACTTCCTGACAAGTACCATGGCTTACAAGATAAG
GAACAAATCTACCGTCAACGCCATTTGGACTTGATTACTAACCGGGAGAGCTATGACCGCTTTGTTACCCGGTCAAAGAT
CATCAGTGAAATCCGTCGTTTCCTCGATCAACGTGGCTACTTAGAAGTGGAAACCCCAGTTTTACATAACATTCCTGGGG
GAGCCAATGCCCGTCCTTTCGTTACTCACCATAATGCTTTAGACATTGATTTATACCTACGTATTGCTTTGGAACTCCAC
CTCAAACGCTTAATCGTCGGAGGAATGGAAAAAGTTTATGAAATTGGTCGGGTCTTCAGAAATGAAGGGATTGACCACAC
CCACAATCCTGAGTTCACCTTGTTAGAACTCTATACTGCTTATAGCGATATGTGGGACGTGATGGACTTAGTCGAAGAAT
TATACCACCATATTGCGAGCCAAGTGGTGGGATCAACCACCATTCCTTATGGAGACCACCAATTAGACTTTTCTGGTCAA
TGGCGCCGGGTCCACATGGTTGACGCTATTAAAGAGGCTACCGGTGTCGACTTCTGGCAAGAAATGACCGATGAAGAAGC
GCGTCAACTAGCCAAAGACCACCATGTTGAAGTCAAAGGTACGGATGACTTTGGTAAGGTGGTTAACGAATTCTTTGAAA
CTTTTGTGGAAGAAACCCTTATTCAACCAACCTTTGTGTATGGTCATCCGAAGTCAATCTCACCATTGGCACGGGCTAAT
GAAGAAGATAGCCGCTTCACCGACCGCTTTGAGGCCTTTATTGCCGGAGCGGAAGCAGGGAACGCCTTTACTGAATTGAC
TGACCCTATCGACCAACGGCAACGCTTTGAAGCCCAAGTCAAGGAAAGAGAATTGGGTGACGATGAAGCCCAACATATGG
ACGAAGACTTCGTGGAAGCTCTGGAAACTGGGATGCCACCAACGGGCGGTTTAGGTATCGGGATTGACCGTTTGGTAATG
ATCTTCACCAACTCCGACTCTATCCGCGACATCCTACTCTTCCCAACCATGCGTAATAAATAA

Protein sequence :
MAKENQQHEAMNDQMQVRREKVDELIENGYQPFAKGFKRDALAQEIHDQYEAFDKDELADKAVFVNIAGRLMTKRGKGRA
GFGHIQDGSGQIQIYVRKDEIGDKDYVDIWKKADLGDIIAVSGYVMRTNTGELSVKAEELKHLTKALRPLPDKYHGLQDK
EQIYRQRHLDLITNRESYDRFVTRSKIISEIRRFLDQRGYLEVETPVLHNIPGGANARPFVTHHNALDIDLYLRIALELH
LKRLIVGGMEKVYEIGRVFRNEGIDHTHNPEFTLLELYTAYSDMWDVMDLVEELYHHIASQVVGSTTIPYGDHQLDFSGQ
WRRVHMVDAIKEATGVDFWQEMTDEEARQLAKDHHVEVKGTDDFGKVVNEFFETFVEETLIQPTFVYGHPKSISPLARAN
EEDSRFTDRFEAFIAGAEAGNAFTELTDPIDQRQRFEAQVKERELGDDEAQHMDEDFVEALETGMPPTGGLGIGIDRLVM
IFTNSDSIRDILLFPTMRNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-112 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_004320843.1 lysine--tRNA ligase VFG1668 Protein 1e-112 48