Gene Information

Name : tkt_2 (HMPREF9243_0260)
Accession : YP_004320630.1
Strain : Aerococcus urinae ACS-120-V-Col10a
Genome accession: NC_015278
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 255626 - 257620 bp
Length : 1995 bp
Strand : +
Note : identified by match to protein family HMM PF00456; match to protein family HMM PF02779; match to protein family HMM PF02780; match to protein family HMM TIGR00232

DNA sequence :
ATGTTTTCAAAAGTTGACAGTTTGGCTGTAGACACTATTCGTATGTTGAGCTTAGACCAGGTCGAAGAAGCTGGAGCAGG
ACATCCAGGAGCGCCTCTTGACCAAGCACCTATGGCTCATGCTTTGTGGACAAAACATTTAAGAGTTAATCCAACTAATC
CTAAATGGTTTAACAGAGATCGCTTTGTTTTATCTTCAGGACATGGCTCTCCGTTAATTTATTCGTTATTACATTTAGCT
GGTTTTAATTTATCGATAGATGATCTAAAACACTTTAGAAAATTTAATTCAAAAACACCTGGGCACCCTGAAGTTACCCA
TACAGAAGGTGTTGAAGCAACTACTGGTCCACTTGGGCAAGGAGTAGCAAATGCAGTTGGTATGGCTATGGCAGAAGCTC
ATTTAGCAGCAATGTTTAACCGGGATAACTATAATGTGGTCGATCACTATACCTATACAATTTGTGGGGATGGCGACCTG
CAAGAAGGTGTTTGCCAAGAAGCATCTAGTTTAGCTGGGCACCTAAAATTAGGGAAACTAATCGTTCTCTATGATTCTAA
TGATGTTCAACTCGATGGGCCAACTAATATGGGCTTTACTGAAGATATTGAAATGAAGTATAAAGCTTATGGATGGCATT
ATCAACGTGTTGAAGATGGAAATGATATGGAGGCTATCAATAAAGCCATTGAAAAAGCTAAGGCTGAAACCGATAAACCT
TCTATTATTGAAATAAAAACAATTATTGGATACGGTATGCCGAATGCAGGCACATCTGATGCCCATAGTGATCCTATTGG
AGCGGAAGGCGTTGCTTATACTAAAAAGCAATATCACTGGACACACGATGAACCTTTCTATGTTCCAGACGAGGTTTACA
ATGTTTATAAAGAAAATGTTGAAAATCGAGGCAGTCAAGCTGAAGAAGAGTGGAACAAATTATTTAAGGGCTATCAAGAA
GCTTATCCAGAATTAGCTGAAGAACTAAGTGCAAGTATTAGAAGAGAATTACCAGACAATTGGGCAGATGAAGTGCCAAA
CTATGAAGTTGGTGATTCAGAATCTACCCGCGATACCAGCAGTCGGATTATAAATGGCATCGCTGAGAAAGTTTCTACAT
TCTGGGGAGGCTCGGCCGATCTCTCTAATTCTAATAAGACAATGATAAAATCAGCAGAAGCATTTACTCCAGATAATTAT
GAAGGAAGAAATATTTGGTATGGTGTTCGTGAATTTGCCATGGGTGCTATCTTGAATGGGATCTTATTACATGGAGGCAC
TTGGTCTTATGTAGGTACTTTCTTTGTATTCTCTGATTATCTGCGCCCTGCAATTCGTTTGGCTGCTTTATCTCAAATAC
CAGCTATTTATGTATTTACCCATGACTCTGTTATTTTAGGATTTGATGGAGCCACACACGAACCTATTGAACATTTTGCA
AGTTATAGAGCTATGCCAAATCTAACAACCTTCAGACCTGCTGATGCTAACGAAGCTGTTGCAGCTTGGAAATTTGCTAT
GGAATCTGAAGACCGTCCGACTATTTTGGCTTTATCTAGACAGGCACTTCCAGTATTAGAAGGAACTGTTAAATATGCTC
AAGATCATGTTGAAAAGGGTGGTTATGTGATTTCTCCCGCTGAAAGTAAAGATTATGATGGAATAATTATTGCCAGCGGT
TCAGAAGTTTCATTGAGCATTGAAGTCCAAAAACAATTAAAAGAAGATGGAATTGATGTAAGCGTAGTCTCAATGCCAAG
TACTGATTTATTTGATTTACAAAGTGACGAATACAAGGAAGCAGTATTACCAAGTAAAATCGAAAAACGTTTAGTAGTGG
AAGCAAGTAATGATCCAGGTTGGGCAAAATACTATGGGTCTAAAGGCAAAGCGTTAGGTATTGAAACATTTGGAATTAGC
GGCGACGGCCAAGAAGTTTATGAATCATTTGGTTACACCGTTGATAAAATTGTTGAAGAATATAAAACTTTGTAA

Protein sequence :
MFSKVDSLAVDTIRMLSLDQVEEAGAGHPGAPLDQAPMAHALWTKHLRVNPTNPKWFNRDRFVLSSGHGSPLIYSLLHLA
GFNLSIDDLKHFRKFNSKTPGHPEVTHTEGVEATTGPLGQGVANAVGMAMAEAHLAAMFNRDNYNVVDHYTYTICGDGDL
QEGVCQEASSLAGHLKLGKLIVLYDSNDVQLDGPTNMGFTEDIEMKYKAYGWHYQRVEDGNDMEAINKAIEKAKAETDKP
SIIEIKTIIGYGMPNAGTSDAHSDPIGAEGVAYTKKQYHWTHDEPFYVPDEVYNVYKENVENRGSQAEEEWNKLFKGYQE
AYPELAEELSASIRRELPDNWADEVPNYEVGDSESTRDTSSRIINGIAEKVSTFWGGSADLSNSNKTMIKSAEAFTPDNY
EGRNIWYGVREFAMGAILNGILLHGGTWSYVGTFFVFSDYLRPAIRLAALSQIPAIYVFTHDSVILGFDGATHEPIEHFA
SYRAMPNLTTFRPADANEAVAAWKFAMESEDRPTILALSRQALPVLEGTVKYAQDHVEKGGYVISPAESKDYDGIIIASG
SEVSLSIEVQKQLKEDGIDVSVVSMPSTDLFDLQSDEYKEAVLPSKIEKRLVVEASNDPGWAKYYGSKGKALGIETFGIS
GDGQEVYESFGYTVDKIVEEYKTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 6e-138 46
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-134 46