Gene Information

Name : aldB (HMPREF9243_1132)
Accession : YP_004321388.1
Strain : Aerococcus urinae ACS-120-V-Col10a
Genome accession: NC_015278
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase B
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.-
Position : 1164008 - 1165489 bp
Length : 1482 bp
Strand : -
Note : identified by match to protein family HMM PF00171

DNA sequence :
ATGGATATTAAAAACCTTAAACTTGAAAAGCGTTATCAATTGTTAATTAATGGTGAATGGACTAATGGCAGCGGTCAAGA
GACGATTGAAGATTATAGCCCGGCAAATGGCGAAAAATTAGCTGAAATTACCGATGCTACTGAGGAAGATGTCAATCAAG
CTGTTGCAGCTGCCCGCCAAGCCTTTCCTAAGTGGGGCAGAACGGATGTCAAAGAAAGAGCTAAAATTCTTAATCAAATT
GCTGATGTTATCGAAGATAACCAAGAGCGTCTGGCTCTAATTGAAACCATGGACAACGGTAAGCCGATTCGAGAAACAGC
AGGGGCTGATATTCCTTTAGCAGCTGACCATTTTCGTTACTTTGCTAGTGTTATCCGTAGCGAAGAAGATCACTTTAAAA
TGCTTGACGACAATACCTTATCCATGGTTCTCCGGGAACCAATTGGCGTTGTCGGCCAGATTATTCCTTGGAACTTTCCC
TTTTTAATGGCAGCTTGGAAAATAGCGCCAGCCTTAGCAGCAGGGGATACTATTGTATTAAAACCCTCCTCTTCCACTTC
TCTAAGCATCCTAGAGTTAGCTAAGTTAATTAATGATCTCTTACCTAAGGGGGTTTTAAATATCATCACTGGAAGTGGAT
CAAAGAGTGGGGAATACCTCCAACACCACCCAGATATTGATAAAATTGCCTTTACTGGATCAACTTCGGTTGGCCGCCAA
GTAGGAATTTCAGCTGCTGAAAACCTCATCCCAGCAACCTTGGAATTAGGTGGAAAATCGGCCAATATTTTCTTTGAAGA
TATGGATATGGAACAAGCCCTAGAAGGAGCTCAATTGGGTATCTTATTCAATCAAGGGGAAGTGTGCTCAGCAGGTTCAC
GAATTTTAGTGCAAGAATCGATCTATGATGAATTTATCGGTCGCTTAAAAGAAGAATTTAAAAAGGTGAAAGTTGGTTTG
CCTTGGGAAAAAGACACTCAACTTGGTGCCCAAGCTAGTCAGGCTCAACATCAAAAGGTGAGCGAATATATTCAAGTGGC
TTTAGATGAAGGAGCTGAAATTATAAGCGGTGGCCATTCAGCATCAGAAGGAGACCTTGAAAAGGGCTATTATTTTGAAC
CTACTTTATTATTAGCAGACAATAGTATGCGGGTGGCTCAAGAAGAAATTTTTGGTCCCGTTGCTACTGTGATTAAATTC
AAAGATGTTGAAGATGCCATCCGTATTGCTAATGATAGTGATTATGGTTTAGCAGGCGGTGTTTTCACTAAAAACTTAGA
CACAGCCTTTAAGGTAGCTCGTGGAGTAAGAACAGGACGAATTTGGATTAATACCTATAATAGCTTTGAAGCTGGGGCAC
CATTTGGAGGCTACAAAGATTCAGGGATTGGTCGAGAAACCCACAAAATGATTCTTAATGCCTATACCCAAGCGAAAAAT
ATCTATATTAATTTAGCTGATGGCAGATCAGGAATGTATTAA

Protein sequence :
MDIKNLKLEKRYQLLINGEWTNGSGQETIEDYSPANGEKLAEITDATEEDVNQAVAAARQAFPKWGRTDVKERAKILNQI
ADVIEDNQERLALIETMDNGKPIRETAGADIPLAADHFRYFASVIRSEEDHFKMLDDNTLSMVLREPIGVVGQIIPWNFP
FLMAAWKIAPALAAGDTIVLKPSSSTSLSILELAKLINDLLPKGVLNIITGSGSKSGEYLQHHPDIDKIAFTGSTSVGRQ
VGISAAENLIPATLELGGKSANIFFEDMDMEQALEGAQLGILFNQGEVCSAGSRILVQESIYDEFIGRLKEEFKKVKVGL
PWEKDTQLGAQASQAQHQKVSEYIQVALDEGAEIISGGHSASEGDLEKGYYFEPTLLLADNSMRVAQEEIFGPVATVIKF
KDVEDAIRIANDSDYGLAGGVFTKNLDTAFKVARGVRTGRIWINTYNSFEAGAPFGGYKDSGIGRETHKMILNAYTQAKN
IYINLADGRSGMY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-112 52
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 8e-115 49
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 8e-115 49
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 8e-115 49
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-114 49
hpaE AAO17179.1 HpaE Not tested tcd island Protein 3e-85 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldB YP_004321388.1 aldehyde dehydrogenase B VFG0082 Protein 3e-112 52